A dynamic growth model of Dunaliella salina: parameter identification and profile likelihood analysis.

Abstract:

:In this work, a photoautotrophic growth model incorporating light and nutrient effects on growth and pigmentation of Dunaliella salina was formulated. The model equations were taken from literature and modified according to the experimental setup with special emphasis on model reduction. The proposed model has been evaluated with experimental data of D. salina cultivated in a flat-plate photobioreactor under stressed and non-stressed conditions. Simulation results show that the model can represent the experimental data accurately. The identifiability of the model parameters was studied using the profile likelihood method. This analysis revealed that three model parameters are practically non-identifiable. However, some of these non-identifiabilities can be resolved by model reduction and additional measurements. As a conclusion, our results suggest that the proposed model equations result in a predictive growth model for D. salina.

journal_name

Bioresour Technol

journal_title

Bioresource technology

authors

Fachet M,Flassig RJ,Rihko-Struckmann L,Sundmacher K

doi

10.1016/j.biortech.2014.08.124

subject

Has Abstract

pub_date

2014-12-01 00:00:00

pages

21-31

eissn

0960-8524

issn

1873-2976

pii

S0960-8524(14)01248-6

journal_volume

173

pub_type

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