Treatment of vitiligo patients by excimer laser improves patients' quality of life.

abstract：BACKGROUND:Laser epilation is now used widely as a clinical alternative to electrolysis for the removal of unwanted hair. All of the laser systems presently being used produce a reliable temporary hair loss by inducing telogen. Most of the published studies use follow-up periods of 6 months or less after the last treat...

journal_title：Journal of cutaneous medicine and surgery

authors： Laughlin SA,Dudley DK

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Linear scleroderma, also known as "en coup de sabre," is a subtype of localized scleroderma that warrants aesthetic correction because it appears on the forehead region in children. OBJECTIVE:To report dermal fat grafting as a novel and effective surgical treatment option in linear scleroderma. METHODS:Und...

journal_title：Journal of cutaneous medicine and surgery

authors： Barin EZ,Cinal H,Cakmak MA,Tan O

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:In 1995, a Rosacea Awareness Program (RAP) was initiated in Canada to make available educational resources for physicians and rosacea patients. Material is in French or English, and is accessible though physician offices and by toll-free telephone. Information was communicated to the public via noncommercial...

journal_title：Journal of cutaneous medicine and surgery

authors： Shear NH,Levine C

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Lichen planopilaris (LPP) is believed to be a follicular variant of lichen planus that affects pilosebaceous units, mainly of the scalp. An extremely rare variant of LPP is a linear form, which follows the lines of Blaschko. Of the five previously documented cases of linear LPP, all were limited to the face....

journal_title：Journal of cutaneous medicine and surgery

authors： Baker K,Pehr K

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:A new treatment for actinic keratoses, ingenol mebutate, was recently approved by the US Food and Drug Administration. OBJECTIVE:To review the mechanisms of action, efficacy and safety data, and practical recommendations for ingenol mebutate. METHODS:The PubMed and clinicaltrials.gov databases were searche...

journal_title：Journal of cutaneous medicine and surgery

authors： Gupta AK,Paquet M

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Moderate to severe chronic hand dermatitis (CHD) is not well controlled by current medical strategies; however, recent studies have shown significant improvement in patients treated with up to 6 months of oral alitretinoin (9-cis-retinoic acid). The results of longer-term continuous treatment are lacking. O...

journal_title：Journal of cutaneous medicine and surgery

authors： Gulliver WP,Baker KA

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Apligraf is a bioengineered skin product composed of neonatal fibroblasts and keratinocytes. The FDA has approved Apligraf for the treatment of chronic venous ulcers and diabetic ulcers. OBJECTIVE:We review the development of bioengineered skin, examine the cellular activities of various growth factors that...

journal_title：Journal of cutaneous medicine and surgery

authors： Shen JT,Falanga V

更新日期：2003-05-01 00:00:00

abstract：:Genital ulcer disease can be caused by a wide variety of sources. Most commonly, genital ulcer disease is grouped into infectious and noninfectious causes. HSV, syphilis, lymphogranuloma venereum, and chancroid represent some common infectious ulcers. Noninfectious causes on the other hand can be inflammatory, noninfl...

journal_title：Journal of cutaneous medicine and surgery

authors： Maliyar K,Mufti A,Syed M,Selk A,Dutil M,Bunce PE,Alavi A

更新日期：2019-11-01 00:00:00

abstract：:Acne is a disease of the pilosebaceous units and these are mainly under hormonal control. In female patients, hormonal therapy is a unique opportunity for the treatment of acne. Several combined oral contraceptives (COCs), cyproterone acetate, spironolactone, flutamide, and others, have been tried for the control of a...

journal_title：Journal of cutaneous medicine and surgery

authors： Poulin Y

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Dermatofibrosarcoma protuberans with fibrosarcomatous differentiation (DFSP-FS) is a rare variant of DFSP with a more aggressive clinical course, characterized by higher rates of local recurrence, metastasis, and death. METHODS:We conducted a clinicopathologic review of all DFSP-FS cases that occurred in Al...

journal_title：Journal of cutaneous medicine and surgery

authors： Kuzel P,Mahmood MN,Metelitsa AI,Salopek TG

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Intralesional Candida antigen has been used as immunotherapy to treat refractory warts in the immunocompetent pediatric and adult populations but has not been reported in individuals with human immunodeficiency virus (HIV). PURPOSE:To examine if Candida antigen resulted in clearance of medically refractory,...

journal_title：Journal of cutaneous medicine and surgery

authors： Wong A,Crawford RI

更新日期：2013-09-01 00:00:00

abstract：:Psoriasis has been associated with a number of behavioral and systemic comorbidities, including psoriatic arthritis, anxiety, depression, obesity, hypertension, diabetes mellitus, hyperlipidemia, metabolic syndrome, smoking, cardiovascular disease, alcoholism, Crohn's disease, lymphoma, and multiple sclerosis. Many of...

journal_title：Journal of cutaneous medicine and surgery

authors： Guenther L,Gulliver W

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Dermoscopy has been shown to be a promising method to facilitate the diagnosis of lichen planus (LP) outside of China. OBJECTIVE:To investigate the spectrum of dermoscopic patterns in Chinese LP patients. METHODS:The clinical data and dermoscopic patterns of nine LP cases with a total of 43 lesions were ev...

journal_title：Journal of cutaneous medicine and surgery

authors： Tan C,Min ZS,Xue Y,Zhu WY

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:It has been demonstrated that hypertrophic scar fibroblasts (HSFs) overexpress collagen messenger ribonucleic acid (mRNA) and protein, especially alpha1 collagen. Antisense nucleic acids are effective in inhibiting harmful or uncontrolled gene expression, suggesting that antisense ribonucleic acid (RNA) can ...

journal_title：Journal of cutaneous medicine and surgery

authors： Ju-Lin X,Shao-Hai Q,Tian-Zeng L,Chao-Quan L,Hou-Dong L,Ying-Bin X,Xu-Sheng L,Bin S,Hui-Zhen L,Yong H

更新日期：2009-05-01 00:00:00

abstract：:We describe a family with supernumerary nipples and kidney and urinary tract malformations. The proband is a 59-year-old man with a supernumerary nipple and recently identified hypoplastic kidney, bladder diverticulum, and hypotonic bladder. His mother also has a supernumerary nipple and a recently identified hypoplas...

journal_title：Journal of cutaneous medicine and surgery

authors： Brown J,Schwartz RA

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Bullous pemphigoid (BP) is an autoimmune polymorphic skin disease characterized by erythematous papules and plaques and tense bullae. A skin biopsy for direct immunofluorescence (DIF) is used to detect autoantibodies and complement proteins. OBJECTIVE:We sought to determine which location would provide the ...

journal_title：Journal of cutaneous medicine and surgery

authors： Sladden C,Kirchhof MG,Crawford RI

更新日期：2014-11-01 00:00:00

abstract：:Psoriasis is a T-cell mediated skin disease that affects approximately 2% of the population worldwide. Despite the prevalence of the disease and long-standing efforts to develop strategies to treat it, there is a need for safe and effective therapies to treat psoriasis, particularly the more severe forms. Biological a...

journal_title：Journal of cutaneous medicine and surgery

authors： Langley RG,Ho V,Lynde C,Papp KA,Poulin Y,Shear N,Toole J,Zip C

更新日期：2006-01-01 00:00:00

abstract：:Atopic dermatitis is one of the most common skin disorders in the developed world, affecting up to 20% of children and 1% to 3% of adults. This review concisely explains the pathophysiology and epidemiology of atopic dermatitis, as well as potential challenges facing its successful treatment. Furthermore, mainstay top...

journal_title：Journal of cutaneous medicine and surgery

authors： Mayba JN,Gooderham MJ

更新日期：2017-05-01 00:00:00

abstract：:The duration of response to treatment with alefacept has been assessed in patients with moderate to severe chronic plaque psoriasis who responded to alefacept therapy in phase 2 and phase 3 clinical studies. In a phase 2 trial, duration of response was based on time to retreatment with alefacept. In two phase 3 studie...

journal_title：Journal of cutaneous medicine and surgery

authors： Krueger GG

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Several clinical trials have established the benefit of using a topical corticosteroid in conjunction with tazarotene gel in the treatment of plaque psoriasis. However, there is little information comparing the relative benefits of different corticosteroids, or different formulations of corticosteroids, when...

journal_title：Journal of cutaneous medicine and surgery

authors： Green L,Sadoff W

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Dabrafenib, a novel selective small-molecule inhibitor of BRAF, has been shown to increase overall survival in patients with unresectable metastatic melanoma harboring the BRAF V600E mutation. The development of resistance has led to combination therapy with selective MEK inhibitor trametinib. Compared with ...

journal_title：Journal of cutaneous medicine and surgery

authors： Lacroix JP,Wang B

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Lichen amyloidosis, a type of primary localized cutaneous amyloidosis, is characterized by pruritic brown or grayish pigmented papules. OBJECTIVE:We report a case of lichen amyloidosis in which the skin lesion consisted of asymptomatic salmon-pink-colored papules on the back of the neck to the upper back. T...

journal_title：Journal of cutaneous medicine and surgery

authors： Sangen Y,Kawada A,Maeda A,Aragane Y,Tezuka T

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Systemic therapy for atopic dermatitis (AD) has been challenging with limited safe and efficacious long-term treatment options. In 2017, dupilumab was approved in the United States, Europe, and Canada as the first targeted therapy for patients with moderate-to-severe AD. Despite promising efficacy and safety...

journal_title：Journal of cutaneous medicine and surgery

authors： Jo CE,Georgakopoulos JR,Ladda M,Ighani A,Mufti A,Drucker AM,Piguet V,Yeung J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Topical minoxidil solution (TMS) is widely used for androgenetic alopecia (AGA), and this is the first report of a large safety trial. OBJECTIVES:The aim of the study was to evaluate the safety profile of TMS by comparing hospitalization and death rates among subjects using TMS with controls. Cardiovascular...

journal_title：Journal of cutaneous medicine and surgery

authors： Shapiro J

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Hypohidrotic ectodermal dysplasia (HED) is a rare multisystem disorder that typically affects hair, teeth, nails, and sweat glands in combination with abnormalities of ectodermal originated tissues. OBJECTIVE:To raise the issue of whether heightened awareness is required in the follow-up of pigmented lesion...

journal_title：Journal of cutaneous medicine and surgery

authors： Gregoriou S,Rigopoulos D,Vergou T,Korfitis C,Menegakis G,Kontochristopoulos G

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Optimal aesthetic results are achieved when nasal defects after Mohs micrographic surgery (MMS) are reconstructed as entire nasal subunits. OBJECTIVE:To illustrate the importance of reconstructing the nose in entire subunits and explore the possibilities of expanding the principles of subunit reconstruction...

journal_title：Journal of cutaneous medicine and surgery

authors： Jergensen ZR,Pezeshk RA,Thornton JF

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Psoriasis in clinical trials is often measured by the Psoriasis Area and Severity Index (PASI). This measurement is well understood by clinical trialists and many dermatologists but rarely by patients and some clinicians. Patients may not understand their chance of improvement based on a PASI-50 or PASI-75 v...

journal_title：Journal of cutaneous medicine and surgery

authors： English PL,Vender R

更新日期：2008-11-01 00:00:00

abstract：:A renaissance is taking place in the field of wound healing. Interest in wounds has probably never been so great, and a number of key therapeutic advances in the last 2 or 3 years are only an indication of more progress to come. In large part, we are benefitting from decades of basic research that has provided the kno...

journal_title：Journal of cutaneous medicine and surgery

authors： Falanga V

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Informed shared decision making is a mutual process engaging both doctor and patient and informed by best medical evidence and patient values and preferences. OBJECTIVE:Our aim was to identify the needs of psoriasis patients in decisions on selecting treatment. METHODS:Psoriasis subjects participated in an...

journal_title：Journal of cutaneous medicine and surgery

authors： Tan J,Stacey D,Fung K,Barankin B,Bissonnette R,Gulliver W,Lui H,Shear N,Jackson C,Zhang X

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Lymphangiosarcoma is a rare, aggressive malignancy that originates from the endothelial cells lining lymphatic vessels and carries an extremely poor prognosis. Its clinical and histologic features are often indistinguishable from angiosarcoma. OBJECTIVE:We sought to better characterize the clinical and hist...

journal_title：Journal of cutaneous medicine and surgery

authors： Mamelak AJ,Collie MR,Kroll R,Hanson ML,Harris HM

更新日期：2014-03-01 00:00:00