Abstract:
:In two previous studies the effects of topically applied 1% and 0.2% solutions of bupranolol on intraocular pressure were investigated in 21 and respectively 20 eyes with chronic uncomplicated open-angle glaucoma.--As early as 30 minutes after both solutions a very significant pressure drop, without concomittant pupillary reaction, was recorded. The 1% bupranolol solution was less well tolerated and caused some ocular irritation. The present study was therefore initiated in order to find out whether a 0.2% solution of bupranolol would yield significantly different results in comparison with the former.--Statistical evaluation, based on variance analysis linked with multiple t-tests, showed a barely significant difference between the pressure-lowering effects of the 1% and 0.2% solutions after one hour, whereas after 2 hours the difference became clearly significant in favour of the 0.2% solution. Furthermore, the 0.2% solution clearly showed a tendency to prolonged duration of effect, beyond the two-hour observation time. It therefore seems justified to supplement the present findings by long-term studies aimed at assessing optimal concentrations of the drug on the one hand, and its long-acting properties on the other. In this way, bupranolol is likely to gain recognition as an antiglaucomatous agent.
journal_name
Klin Monbl Augenheilkdjournal_title
Klinische Monatsblatter fur Augenheilkundeauthors
Oancea I,Trif Vsubject
Has Abstractpub_date
1979-05-01 00:00:00pages
739-44issue
5eissn
0023-2165issn
1439-3999journal_volume
174pub_type
杂志文章abstract::A new measuring system for echo return times is described, which renders it possible to measure simultaneously the three axial lengths of the living eye (length of cornea plus anterior chamber, length of the lens and of the vitreous) with ultrasound in real time and to process the data numerically. The repetition rate...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057620
更新日期:1980-07-01 00:00:00
abstract::The clinical data of 30 eyes with intraocular epithelial invasion were correlated to the histopathological findings (15 iridocyclectomies, four diagnostic iridectomies, one corneal button, ten globes). The diffuse (46.7%) and cystic (53.3%) types occurred with equal frequency. The correlation to the clinical data make...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050215
更新日期:1988-07-01 00:00:00
abstract::Although luetic ocular changes are rarely seen today they should not be neglected in differential diagnosis. Luetic papilledema is extremely rare and neurologic symptoms may be minor. A clinically observed case is described. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-12-01 00:00:00
abstract::Through judgements, the legal system influences medicine and insurance matters strongly, sometimes in a positive way, but sometimes by judgements, which seem to be wrong to the medical expert. Certain institutions lead to the effect that cases are being prevented from judgement by the court and by enactment. This has ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045612
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:In April 1986, numerous reactor workers and firemen were exposed to high doses of ionizing radiation during the Chernobyl nuclear power plant accident. Apart from high ambient gamma-ray exposures they received inhomogeneous contamination with beta-rays from fission products, resulting in severe skin exposure...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1034732
更新日期:1999-12-01 00:00:00
abstract::Examinations of hormone levels in blind persons compared with almost blind and people with normal vision and hormone evaluation with increased artificial light exposure show a definite stimulating effect of light on the human hormonal balance. The effect of light is mediated by an intact perception of light by the eye...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-07-01 00:00:00
abstract:BACKGROUND:Foreign-body-reactions with granulomas after use of silicone-containing biomaterials are of clinical importance [4]. HISTORY AND SIGNS:A 4-year old patient entered our hospital with a reddish vascularised tumor. The tumor's origin was in the conjunctiva of the nasal lid-angle of the right eye. THERAPY AND ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2000-10550
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:Epiphora is the result of hypersecretion or reduced tear outflow because of relative or absolute obstruction of the lacrimal system. For the treatment a specific surgical procedure is usually required. Herein we present the subjective and objective findings of 243 consecutive patients with non-irritative ind...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0029-1245455
更新日期:2010-11-01 00:00:00
abstract::This review article focusses on the management of enhancements after corneal refractive laser surgery. Fundamental issues regarding enhancement embrace identification of the underlying reason for postoperative ametropia, assurance of stability of refraction, type of primary refractive laser treatment and thorough eval...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/a-1148-2744
更新日期:2020-07-01 00:00:00
abstract::The type and extent of bacterial colonization of the conjunctiva at the time of an intraocular operation may have a major influence on the risk of post-operative endophthalmitis. Between March 1986 and December 1988 a total of 7845 preoperative conjunctival smears were therefore examined by culture of Erlangen Univers...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046264
更新日期:1990-08-01 00:00:00
abstract:BACKGROUND:In facial palsies with lagophthalmic keratopathy an hour-glass dressing is indicated, which has the disadvantage of a moisture chamber with visual impairment by steaming up. After weeks of placement dermal irritations are possible. An alternative is the gravity dependent lidloading, using gold implantation i...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035353
更新日期:1995-08-01 00:00:00
abstract:BACKGROUND:The use of virtual reality (VR) has gained increasing interest for the acquirement of ophthalmosurgical skills outside the operating room and is thereby increasing patients' safety. The aim of this study was to evaluate trainees' acceptance of VR for assessment and training during several Drylabs with an oph...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0028-1109383
更新日期:2009-08-01 00:00:00
abstract::The retinal visual acuity of 198 cataractous eyes was tested with interference-fringes and compared with the post-operative visual acuity. A new method of creating interference-fringes was used. The interference-fringe technique showed its special clinical value with immature cataracts. It is of certain value also wit...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-10-01 00:00:00
abstract:BACKGROUND:Age-related macular degeneration (AMD) is a disease with high social impact that severely hinders the quality of life of the affected patients. The aim of our study is to examine the ultrastructural changes in the choroidal neovascular membranes occurring after the intravitreal administration of Avastin. MA...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-0028-1109429
更新日期:2009-06-01 00:00:00
abstract::A rare case of mucopolysaccharidosis, i.e., Morquio's disease with spondyloepiphyseal dysplasia, corneal clouding, normal intelligence, and deficiency of beta-galactosidase activity is described. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1054350
更新日期:1985-11-01 00:00:00
abstract:BACKGROUND:Incomplete removal of the viscoelastic material during cataract surgery may lead to the early postoperative capsular block syndrome. In this retrospective case series, postoperative capsular bag distention after implantation of a foldable acrylic lens is reported and the sequelae are analyzed. PATIENTS AND ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2004-812876
更新日期:2004-05-01 00:00:00
abstract::Basing on the bipolar-coaxial wetfield-diathermy, introduced in microsurgery 1974 by the author, an anterior capsulotomy instrument using a modulated RF-current was published in 1984. In the meantime several patients have been operated successfully with this technique. However, further experimental studies allowed a r...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1045809
更新日期:1992-05-01 00:00:00
abstract::Canaliculitis is a rare disease of the lacrimal pathway, especially of the canaliculi. It is often not identified, therefore misdiagnosed and inadequately treated. It accounts 2 % of all lacrimal diseases. False diagnoses are usually conjunctivitis, blepharitis, dacryocystitis, hordeolum and chalazion. Besides viruses...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1245424
更新日期:2010-07-01 00:00:00
abstract:PURPOSE:Sturge-Weber syndrome is a rare congenital disorder consisting of cutaneous, leptomeningeal and ocular vascular malformations. Glaucoma occurs in 30-70 % of patients. Treatment is challenging due to a high risk of severe complications such as expulsive haemorrhage, massive choroidal effusion and serous retinal ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0032-1315217
更新日期:2012-10-01 00:00:00
abstract::By means of fluorescein angiography extensive defects in the pigmented epithelium found in choroideremia can be shown to be present in the first ten years of life. The degeneration of the vessels of the choroid and the functional damage to the retina do not seem to take place until later. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-04-01 00:00:00
abstract::In an ever-increasing number of the more than 4000 known genetic diseases with Mendelian inheritance, the geneloci have been mapped. In such cases it is possible to predict by DNA techniques whether or not family members are carriers of the mutation and risk having affected children. Using the same methods, disease ca...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1046167
更新日期:1990-05-01 00:00:00
abstract:BACKGROUND:Low-dose oral contraceptives can still cause thromboembolic disorders with serious neurologic or ocular disabilities. PATIENT:A 22-year-old woman having used oral contraceptives for several months noticed sudden painless visual loss in her left eye. One tablet of her contraceptive contained ethinylestradiol...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1273197
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:We report on an eight-year-old boy, who was presented in our clinic because of head turn. The cause of the tortecollis (ocular or general) in this case was and still cannot be explained. Only by applying extensive prism adaptation tests it was possible to prove the ocular character of the head turn. CASE RE...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1027477
更新日期:2008-08-01 00:00:00
abstract::By means of torsional shift operation, or "rotatory Kestenbaum procedure" - in which both ocular bulbs are rotated to the side to which the head is inclined - head malpostures can be eliminated or alleviated in three out of four cases. This applies both to the smaller group of patients with true nystagmus compensation...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1050307
更新日期:1988-12-01 00:00:00
abstract::According to the Lincoff's procedure, a cryoprobe is used for the localization of retinal holes. A cryo-marker developed for Keeler-cryoprobes simplifies the marking of the scleral impression of the cryoprobe, which is often invisible after thawing. The cryo-marker is fixed on the cryoprobe before cryotherapy. During ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1057317
更新日期:1981-10-01 00:00:00
abstract::The 30-prism-test is a relatively quick and simple method for many-sided testing binocular behaviour in near distance in patients with reading difficulties and asthenopic symptoms, respecting well known and assumed causes of the disturbances. Therefore indications for treatment are given. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035556
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:Can the capsulotomy with small radial incisions compared to the continuous curvilinear capsulorhexis with perfect IOL centration still be recommended? This problem should be clarified under standard conditions. METHOD:On 100 patients both procedures were applied alternating with corneoscleral incision, phac...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035520
更新日期:1994-04-01 00:00:00
abstract::We present two further cases of choroiditis geographica. One of them we were able to follow up for two years. This allowed us to observe from the beginning the eye which was not at first involved. Weeks before the first lesions were visible, alterations of the EOG appeared. In the other case both eyes were already inv...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1984-10-01 00:00:00
abstract::Description of a new holder for experimental intraocular surgery on human autopsy eyes. Stability of shape and position of the experimental eyes is achieved by a vacuum surrounding the posterior segment. ...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:
更新日期:1976-03-01 00:00:00
abstract:BACKGROUND:Peripheral exudative haemorrhagic chorioretinopathy (PEHCR) is a degenerative disease of the peripheral retina and choroid in the elderly. Although PEHCR is often seen by clinicians, this entity is underrepresented in the ophthalmological literature. This may be due to inconsistent naming. PATIENTS:We prese...
journal_title:Klinische Monatsblatter fur Augenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0028-1109376
更新日期:2009-08-01 00:00:00