Abstract:
:The amygdala is related with the recognition of the emotional meaning of stimuli, long-term memory, the orientation of social stimuli and the perception of gaze orientation. It plays a fundamental role in the recognition of faces, especially those expressing fear, and makes it possible to comprehend different emotional states, which will facilitate an appropriate social cognition. Dysfunctions of the amygdala have been associated to a number of different neurodevelopmental disorders as well as neurocognitive and behavioural disorders in specific neurogenetic entities. A number of studies focused on the amygdalic complex have allowed researchers to understand many pathophysiological aspects and to formulate new hypotheses regarding their origins. Given that the disorders or conditions in which the role of the amygdala has been evoked are becoming increasingly more extensive, this article refers the reader to those that have aroused the most interest in recent years. Thus, they can be divided into two groups: developmental and behavioural disorders (autism, anxiety disorders, bipolar disorder, alexithymia and anorexia nervosa) and specific neurogenetic entities (fragile X, Rett, Prader-Willi and Williams syndromes), in which structural or dysfunctional alterations have been observed that may be related with their neurocognitive and behavioural symptoms. It is important to remember that the amygdala is a highly connected structure that forms truly functional networks and has been associated to different disorders with varied explanations and includes several different pathophysiological phenomena. Its role must not, therefore, be simplified in a reductionistic manner, but also placed upon a hierarchy of dysfunctions in other areas that interact with it. TITLE:La amigdala y su relacion con el autismo, los trastornos conductuales y otros trastornos del neurodesarrollo. :La amigdala esta relacionada con el reconocimiento del significado afectivo del estimulo, la memoria a largo plazo, la orientacion del estimulo social y la percepcion de orientacion de la mirada. Desempeña un papel fundamental en el reconocimiento de caras, en especial la de temor, y permite la comprension de diversos estados emocionales, los cuales facilitaran una adecuada cognicion social. Disfunciones de la amigdala se han relacionado con diversos trastornos del neurodesarrollo y con alteraciones neurocognitivas y conductuales en entidades neurogeneticas especificas. Multiples estudios focalizados en el complejo amigdalino han permitido comprender muchos aspectos fisiopatologicos y formular nuevas hipotesis en relacion con su genesis. Dado que los trastornos o entidades en que se ha evocado el papel de la amigdala son cada vez mas extensos, este articulo remite a aquellos que han despertado mayor interes en los ultimos años, dividiendolos en dos grupos: trastornos del desarrollo y conductuales (autismo, trastornos de ansiedad, trastorno bipolar, alexitimia y anorexia nerviosa), y entidades neurogeneticas especificas (sindromes del cromosoma X fragil, Rett, Prader-Willi y Williams), en las cuales se han comprobado alteraciones estructurales o disfunciones que pueden relacionarse con la sintomatologia neurocognitiva y conductual de estas. Es importante recordar que la amigdala es una estructura altamente conectada que conforma verdaderas redes funcionales, se ha asociado a diversos trastornos cuya explicacion es variada e incluye diversos fenomenos fisiopatologicos, por lo que no debe simplificarse de una forma reduccionista su papel, sino tambien jerarquizar disfunciones de otras areas que interactuan con ella.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Ruggieri VLsubject
Has Abstractpub_date
2014-02-24 00:00:00pages
S137-48eissn
0210-0010issn
1576-6578pii
rn2013571journal_volume
58 Suppl 1pub_type
杂志文章,评审abstract:INTRODUCTION:«Man-in-the-barrel» syndrome refers to diplegia of the upper extremities in which mobility of the head and lower limbs is preserved. Brachial plexitis that presents as «man-in-the-barrel» syndrome is an unusual manifestation of giant cell arteritis. We report a case of C5-C6 plexitis as part of the clinica...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2018-06-01 00:00:00
abstract:INTRODUCTION AND DEVELOPMENT:Psychostimulant drugs encompass amphetamines, natural alkaloids like cocaine, and methyl-xanthynes. These drugs induce a strong dependence, manifested as sensitization and tolerance at a neurobiological level. Sensitization is currently being studied experimentally, and it is made up of two...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-08-01 00:00:00
abstract::Autonomic dysfunction is a common manifestation in patients with in Parkinson's disease, which can sometimes precede motor impairment. It can be expressed as orthostatic and postprandial hypotension, supine hypertension, hypersalivation, constipation, delayed gastric emptying, dyshidrosis, bladder and sexual dysfuncti...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2015-04-16 00:00:00
abstract:TITLE:Facilitar el acceso a toda la informacion debe ser una obligacion para las revistas medicas. : ...
journal_title:Revista de neurologia
pub_type: 信件
doi:
更新日期:2018-02-16 00:00:00
abstract::The neuropathology of haemorrhagic and hypoxic-ischaemic perinatal encephalopathies and their effect on the post-natal development of the brain, has been studied in children who survived with these lesions (for days, weeks, months and even years). Eventually some children developed neurological sequelae, including epi...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract:INTRODUCTION:The thoracic outlet syndromes are clinical conditions whose true incidence is low, although they are frequently diagnosed. They are caused by compression of the brachial plexus or vascular structures due to anatomical anomalies of the cervico-axillary region. DEVELOPMENT:Two main types are seen: the neuro...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1998-07-01 00:00:00
abstract:INTRODUCTION:Diagnosing Alzheimer's disease (AD) as soon as possible is critical to achieve an effective treatment of patients. AIM:To make up a test capable of differentiating those patients suffering from the early stages of AD compared to healthy people or patients with mild cognitive impairment (MCI). SUBJECTS AN...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2007-04-16 00:00:00
abstract:OBJECTIVE:To present a case with several cutaneous hemangiomas associated with intracranial hemangiomas and possibly with an intrahepatic hemangioma. CASE REPORT:A boy, 17 months old, showing several cutaneous hemangiomas and epileptic seizures resisting to antiepileptic medication, who also presented psychomotor reta...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract:PURPOSE AND SETTING:To describe the prevalence and risk factors for carotid stenosis in TIA/stroke patients with non valvular atrial fibrillation (AF) and to compare clinical and CT characteristics of TIA/stroke in AF patients with and without carotid stenosis. SUBJECTS:50 TIA/stroke patients with AF who had ultrasoun...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:INTRODUCTION:Chronic intoxication due to carbon monoxide (CO) is a condition in which the frequency is underestimated since the clinical features are nonspecific. It is important since serious neurological sequelae may result: an extrapyramidal syndrome, dementia or a vegetative state. The diagnosis is established when...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-02-16 00:00:00
abstract:INTRODUCTION:Surgery for resection of supratentorial lesions near the motor areas and/or internal capsule carries an associated risk of damage to cortical or subcortical motor pathways. Intraoperative brain mapping, using direct cortical electric stimulation, is a surgical adjunct used during lesionectomy in functional...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2009-06-16 00:00:00
abstract:AIMS:The purpose of this work was to gather the information currently available about the content of nerve growth factor (NGF) in experimental models of neurodegeneration and in neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases, as well as to analyse how NGF content is affected by...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2004-05-16 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:When the clinical picture consists of prominent cognitive impairments (e.g. amnesia) with relatively mild behavioral symptoms, it can be very difficult to distinguish frontal lobe dementia (FLD) from Alzheimer disease (AD). However, these conditions may have distinct cognitive profiles that c...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract:INTRODUCTION:Visual phenomena can be symptoms of epileptic seizures, although with an uncertain clinical meaning and relationship with the epileptogenic focus. AIMS:To describe the clinical implications of visual epileptic seizures according to their signs and symptoms in adults. PATIENTS AND METHODS:Data were collec...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2015-03-16 00:00:00
abstract:INTRODUCTION:The impossibility of treating patients with sleep disorders adequately means that, as specialists, we have to look for new pharmacological treatments and for this reason we examined the information in the paper by Salin Pascual (1999) about the increase in deep sleep when olanzapine is used as an antipsych...
journal_title:Revista de neurologia
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract:INTRODUCTION:Strachan's disease is a condition which mainly affects the nervous system. It is characterized by optic, auditory and peripheral neuropathies and lesions of the skin and mucous membranes. In 1955 Miller Fisher gave it this name, since the clinical condition described by Henry Strachan in Jamaica during the...
journal_title:Revista de neurologia
pub_type: 历史文章,杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract:INTRODUCTION:Thymectomy is a surgical procedure which is generally accepted for treatment of myasthenia gravis. OBJECTIVE:To describe the long-term evolution of 217 myasthenic patients who had had thymectomies in the Hospital Clinico Quirurgico Hermanos Ameijeiras in La Habana, Cuba. PATIENTS AND METHODS:We determine...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-05-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:The objective of the study was to analyze the EEG tracings during the seizures of two monozygotic twins, shown on molecular analysis, diagnosed as having infantile epilepsy with absences. The recordings are particularly interesting since the genotypes of the patients are identical. This allow...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-12-16 00:00:00
abstract:INTRODUCTION:Although subjective memory complaints are one of the most common causes behind visits to health services, there are hardly any validated instruments in Spanish for evaluating their magnitude. Since memory complaint questionnaires usually include items referring to attentional and executive aspects, it has ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract:INTRODUCTION:Over the last twenty years much work has been done to study the P300 in alcoholism. A systematically reduced amplitude, both in patients and in populations at risk (children of alcoholics) was found. Besides, studies on twins indicate that the waves of the evoked potentials are under genetic control. Furth...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2000-04-16 00:00:00
abstract:INTRODUCTION:Generalised dystonia is an entity that does not usually respond well to medical treatment. Different surgical targets have therefore been used in the treatment of dystonia, including several thalamic nuclei or the internal globus pallidus. The subthalamic nucleus plays a fundamental role in the physiology ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-09-16 00:00:00
abstract:INTRODUCTION:Traumatic brain injury (TBI) is a common cause of death and disability in the paediatric population, although the literature on the Spanish population is scarce. From the perspective of early vulnerability, recent research findings suggest that early brain injury has worse sequelae and a higher risk of imp...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:10.33588/rn.7007.2019393
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:Ocrelizumab is a humanised monoclonal antibody that targets the CD20 antigen on B cells. It has recently been approved by the US (Food and Drug Administration) and European health agencies (European Medicines Agency) for the treatment of multiple sclerosis (MS) and is the first drug marketed for both relap...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2018-06-16 00:00:00
abstract:AIM:To report a case of sub-acute encephalopathy with all the extension study negative and with response to steroid therapy. CASE REPORT:The study involves a 22-year-old female with no relevant past history who presented symptoms of sub-acute encephalopathy consisting in behavioural disorders, generalised seizures and...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2009-10-01 00:00:00
abstract:TITLE:Polimiositis secundaria a un linfoma no Hodgkin. : ...
journal_title:Revista de neurologia
pub_type: 信件
doi:
更新日期:2017-04-01 00:00:00
abstract:INTRODUCTION:Understanding how the human motor control operates is an important issue to the neuroscience. One example is how the motor cortex controls muscle activity, which can be observed through corticomuscular coherence (CMC). AIM:Our study aimed to verify the influence of certain factors related to the fine moto...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2010-11-16 00:00:00
abstract:INTRODUCTION:Several studies have found that individuals with multiple sclerosis (MS) experience relatively high rates of anxiety and depression; however, there are few reports about social anxiety in individuals with MS. AIM:To analyze the prevalence of social anxiety disorder and other psychiatric comorbidities in M...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:10.33588/rn.7002.2019213
更新日期:2020-01-16 00:00:00
abstract:INTRODUCTION:Devic's optic neuromyelitis is an unusual condition characterized by the association of unilateral or bilateral optic neuritis and myelitis, both of which are relapsing. Prognosis is usually poor, both for the optic nerve and for the spinal medulla which becomes cavitated. This leads to severe handicap and...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-03-01 00:00:00
abstract:INTRODUCTION:Congenital hydrocephalus or ventriculomegaly is a disorder that now can be diagnosed in uterus with ultrasonography, this gives the chance of being able to give a treatment the earliest as possible. DEVELOPMENT:The clinical manifestations are reviewed, the diagnosis, the frequent treatment and causes of c...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-04-10 00:00:00
abstract:OBJECTIVE:To determine clinical and pathological features with seizures associated brain tumors. PATIENTS AND METHODS:This was a retrospective study through of an Epilepsy Program Protocol where we studied fifty patients admitted at Hospital Universitário Cajuru of Curitiba, Brazil, in 1996-1997. RESULTS:We studied 3...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00