Microdrive and method for single unit recording in the active rat.

Abstract:

:A technique for recording single unit activity in the active rat with microelectrodes is described. The microdrive used is small and light enough to be carried in a well that is chronically implanted on the head of the rat. The device permits standard microelectrodes to be lowered without rotation, a feature which reduces chance of damage to the fine tips and to the brain tissue. The microdrive itself may be rotated in the well and several penetrations in a single preparation are possible. The electrodes used are capable of recording unit activity of high amplitude and stability. Units may be held for minutes or hours depending on the intensity of the rat's behavior.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Sinnamon HM,Woodward DJ

doi

10.1016/0031-9384(77)90296-7

subject

Has Abstract

pub_date

1977-09-01 00:00:00

pages

451-3

issue

3

eissn

0031-9384

issn

1873-507X

pii

0031-9384(77)90296-7

journal_volume

19

pub_type

杂志文章
  • Pontine and thalamic influences on fluid rewards: I. Operant responding for sucrose and corn oil.

    abstract::The reward strength of orosensory sucrose and corn oil was measured using fixed and progressive ratio operant schedules. Because the orosensory effects of the stimuli were of interest, Experiment 1 compared operant responses for sucrose in sham and real feeding rats. The results demonstrated that rats would work for s...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2011.06.010

    authors: Liang NC,Freet CS,Grigson PS,Norgren R

    更新日期:2012-01-18 00:00:00

  • Penile mechanisms and the role of the striated penile muscles in penile reflexes.

    abstract::Gross and subgross anatomical observations of the penis pointed to a mechanical arrangement whereby contraction of the bulbocavernosus (BC) muscles would enhance erections of the glans penis and contraction of the ischiocavernosus (IC) muscles would enhance or produce penis flips. These functions for the muscles were ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(83)90277-9

    authors: Hart BL,Melese-D'Hospital PY

    更新日期:1983-12-01 00:00:00

  • Consumption of electrolytes and quinine by mouse strains with different blood pressures.

    abstract::Daily fluid intakes were measured using two-bottle tests in female mice of inbred strains with high (BPH/2), normal (BPN/3) or low (BPL/1) blood pressure. The mice were offered a choice between water and different concentrations of NaCl (37.5-600 mM), KCl (1-400 mM), CaCl2 (1-100 mM) and quinine hydrochloride (0.003-1...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(98)00069-9

    authors: Bachmanov AA,Schlager G,Tordoff MG,Beauchamp GK

    更新日期:1998-06-01 00:00:00

  • Chronic salt-loading reduces basal excitatory input to CRH neurons in the paraventricular nucleus and accelerates recovery from restraint stress in male mice.

    abstract::Neurons synthesizing corticotrophin-releasing hormone (CRH) in the paraventricular nucleus of the hypothalamus (PVN) are activated during acute stress and act via the hypothalamic-pituitary-adrenal (HPA) axis to increase systemic levels of corticosterone (CORT). Recent data indicates that CRH neurons in the PVN are in...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2017.03.038

    authors: Krause EG,Pati D,Frazier CJ

    更新日期:2017-07-01 00:00:00

  • Effects of polychlorinated biphenyls on maternal odor conditioning in rat pups.

    abstract::Polychlorinated biphenyls (PCBs) are pervasive environmental contaminants that can have damaging effects on physiologic, motoric and cognitive function. Results from studies on PCBs and behavior have shown that exposure can alter learning and memory processes and that these shifts in cognitive abilities can be related...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2007.03.029

    authors: Cromwell HC,Johnson A,McKnight L,Horinek M,Asbrock C,Burt S,Jolous-Jamshidi B,Meserve LA

    更新日期:2007-08-15 00:00:00

  • Temporal organization: A novel mechanism of hormonal control of male-typical sexual behavior in vertebrates.

    abstract::In vertebrates, male-typical sexual behavior (MSB) is largely controlled by gonadal androgens, however, the mechanism of this control is believed to vary among species. During immediate activation MSB is tightly correlated with circulating levels of androgens, while the organization of MSB by a hormonal event at a spe...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2016.12.030

    authors: Schořálková T,Kratochvíl L,Kubička L

    更新日期:2017-03-01 00:00:00

  • Food restriction alters the diurnal distribution of sleep in rats.

    abstract::The purpose of the present study was to determine the effects of restricting food and water intake to the light period on sleep and brain temperature (Tbr). Sprague-Dawley male rats were anesthetized and provided with electrodes and thermistors for electroencephalographic (EEG) and Tbr recordings. Baseline recordings ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(99)00137-7

    authors: Roky R,Kapás L,Taishi TP,Fang J,Krueger JM

    更新日期:1999-11-01 00:00:00

  • Reduced basal GABA concentrations in the rat amygdala during pregnancy.

    abstract::Marked increases in anxiety-like responses to stress occur during pregnancy. Considerable evidence indicates that the basolateral region of the amygdala (BLA) plays an important role in mediating these types of responses. Given the crucial inhibitory influence of GABA on excitatory glutamatergic activity in the BLA, w...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2006.01.011

    authors: Young BJ,Cook CJ

    更新日期:2006-04-15 00:00:00

  • Water adulteration with citric acid: effects on drinking and responsivity to regulatory challenges.

    abstract::Rats with permanent access to a water supply adulterated with citric acid (CA) displayed persistent reductions in fluid intake and fluid/food ratios; and at appropriate concentrations of CA, they also exhibited lowered body weights and drinking deficits after fluid deprivation and after hypertonic NaCl injections. Unl...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(86)90025-9

    authors: Watson PJ,Beatey S,Wagner F,Stahl T

    更新日期:1986-01-01 00:00:00

  • Morphine and dextrorphan lose antinociceptive activity but exhibit an antispastic action in chronic spinal rats.

    abstract::Within 3-4 weeks after spinal transection, morphine-induced antinociception, assessed with the tail flick reflex in rats, is profoundly reduced. The cause of this decrement is unknown. The present studies were conducted to determine whether this phenomenon reflects a general loss in opiate activity or a selective decl...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(97)00240-0

    authors: Advokat C,Mosser H,Hutchinson K

    更新日期:1997-10-01 00:00:00

  • The corticomedial amygdala and learning in an agonistic situation in the rat.

    abstract::Social agonistic behaviour of intact male rats is strongly reduced by the experience of defeat by a dominant male conspecific. Small electrolytic lesions in the corticomedial amygdala strongly affected this behavioural change due to defeat. No effects of the lesions were observed before and during the defeat. Some lea...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(84)90311-1

    authors: Bolhuis JJ,Fitzgerald RE,Dijk DJ,Koolhaas JM

    更新日期:1984-04-01 00:00:00

  • Male and female 5-HT(1B) receptor knockout mice have higher body weights than wildtypes.

    abstract::5-HT(1B) receptors have a regulatory role in serotonergic activity and influence feeding behavior and body weight. Because the absence of 5-HT(1B) receptors may cause changes in this regulation, body weight was measured in male and female 5-HT(1B) receptor knockout (5-HT(1B) KO) and wildtype (WT) mice from weaning unt...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(01)00589-3

    authors: Bouwknecht JA,van der Gugten J,Hijzen TH,Maes RA,Hen R,Olivier B

    更新日期:2001-11-01 00:00:00

  • Opioid mechanisms that mediate the palatability of and appetite for salt in sodium replete and deficient states.

    abstract::Sodium deficiency reliably produces a robust intake of saline in rats, which is associated with an increased preference for sodium solutions at hypertonic concentrations that would normally be avoided. The mechanisms underlying the shift to an increased preference for sodium in the deficient state are not well underst...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2012.01.019

    authors: Na ES,Morris MJ,Johnson AK

    更新日期:2012-05-15 00:00:00

  • A comparative study of the effect of starvation regimes on the foraging behavior of Portunus trituberculatus and Charybdis japonica.

    abstract::Predation of manila clams (Ruditapes philippinarum) by swimming crabs (Portunus trituberculatus) and Japanese stone crabs (Charybdis japonica) was compared in the laboratory under different starvation regimes by a video recording analysis system, and the mechanism of foraging behavior differences between them combined...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2015.07.011

    authors: Sun Y,Wang F,Dong S

    更新日期:2015-11-01 00:00:00

  • Positive effects of acarbose in the diabetic rat are not altered by feeding schedule.

    abstract::We previously demonstrated that chronic dietary treatment with acarbose, an alpha-glucosidase inhibitor, improves glucose homeostasis in the streptozotocin (STZ)-induced diabetic rat. In this study we evaluated the effects of 4 weeks of acarbose treatment on glucose homeostasis in STZ-diabetic rats for both meal-fed (...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(98)00013-4

    authors: Wright BE,Vasselli JR,Katovich MJ

    更新日期:1998-03-01 00:00:00

  • Short-term consumption of a diet rich in fat decreases anxiety response in adult male rats.

    abstract::Short- and long-term changes in the composition of dietary macronutrients [protein (P), carbohydrate (C), and fat (F)] alter neurochemistry and behavior in animals. We examined whether short-term intake of a diet rich in P, C, or F affected their anxiety response (AR). AR of Sprague-Dawley rats was measured in an elev...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(96)00135-7

    authors: Prasad A,Prasad C

    更新日期:1996-09-01 00:00:00

  • Effect of diet upon ventilation and effort perception during a physical stressor.

    abstract::The present research explored the effects of a high and low carbohydrate diet on ratings of perceived exertion (RPE) during a 10 minute bicycle ergometer test at high physical work capacity (70% of maximum aerobic capacity). Twelve female student volunteers participated and were randomly assigned the order of diet tre...

    journal_title:Physiology & behavior

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0031-9384(85)90140-4

    authors: Demeersman R,Schaefer DC,Miller WW

    更新日期:1985-10-01 00:00:00

  • Social stability attenuates the stress in the modified multiple platform method for paradoxical sleep deprivation in the rat.

    abstract::The instrumental methods to induce paradoxical sleep (PS) deprivation are stressful. The modified multiple platform method (MMPM), in which animals are placed with new cohorts inside the water tanks, results in augmented ACTH and corticosterone (CORT) responses. We hypothesised that this increased response could be at...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(99)00181-x

    authors: Suchecki D,Tufik S

    更新日期:2000-01-01 00:00:00

  • Newborn rats' first suckling experience: taste differentiation and suckling plasticity.

    abstract::The present study examined responsiveness of newborn rats to a surrogate nipple providing fluids with basic tastes (sweet, sour, bitter and salty) and assessed the effects of this first gustatory experience on subsequent responding to the nipple itself (empty nipple) or the nipple providing water. Responsiveness (atta...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(01)00672-2

    authors: Nizhnikov ME,Petrov ES,Varlinskaya EI,Spear NE

    更新日期:2002-06-01 00:00:00

  • Influence of photoperiod, green food, and water availability on reproduction in male California mice (Peromyscus californicus).

    abstract::California mice (Peromyscus californicus) breed primarily during the winter rainy season and generally terminate breeding during the dry summer months. This pattern of reproduction could be regulated by day length, availability of green vegetation, or water availability. The effects of photoperiod and green vegetation...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)00380-n

    authors: Nelson RJ,Gubernick DJ,Blom JM

    更新日期:1995-06-01 00:00:00

  • The inhibitory effects of fluprazine on parental aggression in female mice are dependent upon intruder sex.

    abstract::Lactating resident mice respond differently to male and female intruder conspecifics, showing defensive attack towards the former and offensive attack towards the latter. The effects of fluprazine (1-5 mg/kg) on this differential response pattern have been assessed. Although fluprazine increased the latencies of attac...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(89)90020-6

    authors: Parmigiani S,Rodgers RJ,Palanza P,Mainardi M,Brain PF

    更新日期:1989-09-01 00:00:00

  • Antidepressant effect of ingested nicotine in female rats of Flinders resistant and sensitive lines.

    abstract::Both major depression and depressive symptoms are associated with a high rate of nicotine dependence, and a history of major depression has an adverse impact on smoking cessation. The main objective of this study was to investigate whether continuous ingestion of nicotine affects indices of depressive behavior in the ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(99)00091-8

    authors: Djurić VJ,Dunn E,Overstreet DH,Dragomir A,Steiner M

    更新日期:1999-10-01 00:00:00

  • Ratings of perceived recovery and exertion in elite youth soccer players: Interchangeability of 10-point and 100-point scales.

    abstract::The purpose of this study was to examine the interchangeability of a new perceived recovery status scale (PRS) of 100 points through a comparison to the original 10-point version. This study also aimed to test the interchangeability of CR100 scale (Borg's rate of perceived exertion scale) in comparison to the CR10. Tw...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.112641

    authors: Clemente FM,Rabbani A,Araújo JP

    更新日期:2019-10-15 00:00:00

  • Maternal resistance exercise promotes changes in neuroplastic and epigenetic marks of offspring's hippocampus during adult life.

    abstract::Studies indicate that gestational exercise practice positively impacts the offspring's cognition. Nevertheless, the influence of maternal resistance exercise, different periods of exercise practice, and the inter- and transgenerational effects involved in these responses are not known. This study sought to report the ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2020.113306

    authors: Meireles ALF,Segabinazi E,Spindler C,Gasperini NF,Souza Dos Santos A,Pochmann D,Elsner VR,Marcuzzo S

    更新日期:2021-03-01 00:00:00

  • Dietary aspartame with protein on plasma and brain amino acids, brain monoamines and behavior in rats.

    abstract::Aspartame (APM; L-aspartyl-L-phenylalanine methyl ester), was investigated for its ability to alter levels of the large neutral amino acids and monoamines in overnight fasted rats allowed to consume meals with or without protein for two hours. Additionally, the possible long term behavioral consequences of APM in 25% ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(86)90366-5

    authors: Torii K,Mimura T,Takasaki Y,Ichimura M

    更新日期:1986-01-01 00:00:00

  • Role of estradiol withdrawal in 'anhedonic' sucrose consumption: a model of postpartum depression.

    abstract::Previously, a hormone-simulated pregnancy (HSP), and the subsequent 'postpartum' withdrawal in estradiol has been shown to precipitate depressive-like behaviours in the forced swim test in female rats. In this study, we used the HSP and 'postpartum' withdrawal to investigate the impact on sucrose consumption, a model ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2009.02.020

    authors: Green AD,Barr AM,Galea LA

    更新日期:2009-05-25 00:00:00

  • Consequences of VGluT3 deficiency on learning and memory in mice.

    abstract::The aim of the present study was to test the hypothesis that vesicular glutamate transporter 3 (VGluT3) deficiency is associated with cognitive impairments. Male VGluT3 knockout (KO) and wild type (WT) mice were exposed to a behavioral test battery covering paradigms based on spontaneous exploratory behavior and reinf...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.112688

    authors: Fazekas CL,Balázsfi D,Horváth HR,Balogh Z,Aliczki M,Puhova A,Balagova L,Chmelova M,Jezova D,Haller J,Zelena D

    更新日期:2019-12-01 00:00:00

  • Effects of intracerebroventricular injection of dynorphin, leumorphin and alpha neo-endorphin on operant feeding in pigs.

    abstract::Young pigs, which are useful experimental animals for biomedical research, were prepared with lateral intracerebroventricular (ICV) cannulae and housed individually in cages fitted with operant panels, with food and water ad lib. ICV injection of 200 micrograms of dynorphin A 1-17 or 1-13 resulted in a significant mea...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(90)90233-t

    authors: Baldwin BA,de la Riva C,Ebenezer IS

    更新日期:1990-12-01 00:00:00

  • Facilitation of thermoregulatory heating behavior by single cortical spreading depression in the rat.

    abstract::Effects of single waves of unilateral cortical spreading depression (CSD) on skin-heating behavior were studied in the rat with the unilateral lesion in the preoptic and anterior hypothalamus (PO/AH). A single CSD contralateral to the PO/AH lesion significantly increased the number of heating for 4 min after CSD had e...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:

    authors: Shibata M,Hori T,Kiyohara T,Nakashima T

    更新日期:1983-11-01 00:00:00

  • Oral processing assessed by M-mode ultrasound imaging varies with food attribute.

    abstract::Ultrasonic imaging was used to quantify oral movements made during the oral processing of foods while subjects assessed the intensity of the sensory attributes, thick, creamy, sweet and bitter. A series of four stimuli were prepared with high and low viscosities and high and low sweetness. Over five sessions, subjects...

    journal_title:Physiology & behavior

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.physbeh.2006.05.021

    authors: de Wijk RA,Wulfert F,Prinz JF

    更新日期:2006-08-30 00:00:00