Abstract：
BACKGROUND:Comorbidities including hearing impairment occur commonly in individuals with cerebral palsy (CP). METHODS:Hearing impairment was assessed in a registry-derived population-based sample of children with CP. RESULTS:Hearing impairment was documented in 12.7% (27 of 212) with less than a quarter of these (or 2.7% overall [6 of 212]) having a severe hearing loss of greater than 70 dB bi-aurally. Those with severe hearing impairment were more likely to be nonambulatory (Gross Motor Function Classification System IV/V; 100% versus 34.0% in the registry; P < 0.001) and have a spastic quadriplegic or dyskinetic CP variant (100% versus 42%, P = 0.001). Severe neonatal hyperbilirubinemia necessitating exchange transfusion demonstrated a striking association with hearing impairment in the context of CP in spite of small observed numbers; three of three had severe hearing loss, accounting for 50% of cases of severe hearing loss. CONCLUSIONS:These results suggest a specific CP context and antecedent conditions that necessitate a heightened vigilance for the detection and remediation of hearing impairment.
journal_name
Pediatr Neuroljournal_title
Pediatric neurologyauthors
Dufresne D,Dagenais L,Shevell MI,REPACQ Consortium.doi
10.1016/j.pediatrneurol.2014.07.005subject
Has Abstractpub_date
2014-11-01 00:00:00pages
641-4issue
5eissn
0887-8994issn
1873-5150pii
S0887-8994(14)00403-2journal_volume
51pub_type
杂志文章abstract：BACKGROUND:Autosomal recessive or X-linked inborn errors of intracellular cobalamin metabolism can lead to methylmalonic aciduria and homocystinuria. In neonates, both increased cerebrospinal fluid glycine and cerebrospinal fluid/plasma glycine ratio are biochemical features of nonketotic hyperglycinemia. METHODS:We d...
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journal_title：Pediatric neurology
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journal_title：Pediatric neurology
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journal_title：Pediatric neurology
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journal_title：Pediatric neurology
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journal_title：Pediatric neurology
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pub_type： 杂志文章,评审
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更新日期：2001-08-01 00:00:00
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journal_title：Pediatric neurology
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journal_title：Pediatric neurology
pub_type： 杂志文章
doi：10.1016/j.pediatrneurol.2011.12.009
更新日期：2012-03-01 00:00:00
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journal_title：Pediatric neurology
pub_type： 杂志文章,评审
doi：10.1016/s0887-8994(01)00322-8
更新日期：2002-01-01 00:00:00
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journal_title：Pediatric neurology
pub_type： 杂志文章,评审
doi：10.1016/0887-8994(93)90046-f
更新日期：1993-03-01 00:00:00
abstract：:A 16-month-old girl with a history of Prader-Willi syndrome and progressive macrocephaly manifested large, bilateral, subdural hemorrhages of differing ages on magnetic resonance imaging. Subsequent evaluation revealed a deficiency of von Willebrand factor, but after repeated evaluations, no conclusive evidence of non...
journal_title：Pediatric neurology
pub_type： 杂志文章,评审
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journal_title：Pediatric neurology
pub_type： 杂志文章
doi：10.1016/0887-8994(88)90006-9
更新日期：1988-05-01 00:00:00
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journal_title：Pediatric neurology
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更新日期：2006-05-01 00:00:00
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journal_title：Pediatric neurology
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更新日期：1988-01-01 00:00:00
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journal_title：Pediatric neurology
pub_type： 杂志文章
doi：10.1016/j.pediatrneurol.2016.09.009
更新日期：2017-01-01 00:00:00
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journal_title：Pediatric neurology
pub_type： 杂志文章
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更新日期：1997-11-01 00:00:00
abstract：:The mechanisms of death and neurologic sequelae in African children with cerebral malaria are undetermined. Because pathologic features are confined to the cerebral vasculature, perturbations in cerebral hemodynamics may be responsible. We compared the transcranial Doppler findings in 50 children with cerebral malaria...
journal_title：Pediatric neurology
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journal_title：Pediatric neurology
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更新日期：2003-09-01 00:00:00
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journal_title：Pediatric neurology
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更新日期：2020-09-01 00:00:00
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journal_title：Pediatric neurology
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journal_title：Pediatric neurology
pub_type： 杂志文章,评审
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journal_title：Pediatric neurology
pub_type： 杂志文章
doi：10.1016/j.pediatrneurol.2020.02.007
更新日期：2020-07-01 00:00:00
abstract：:We describe eight cases of pediatric patients whose neuroimages performed after seizures revealed abnormalities that were compatible with edema surrounding calcified lesions and which disappeared in subsequent examinations. ...
journal_title：Pediatric neurology
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