Endocrine influences on the actions of morphine. III. Responses to hypothalamic hormones.

abstract：:In order to search for candidate genes related to pituitary adenoma aggressiveness, the present investigation was intended to compare the mRNA expression profile from a pool of four nonfunctional pituitary adenomas (NFPA) with a spinal cord metastasis of a nonfunctional pituitary carcinoma (MNFPC). The metallothionein...

journal_title：Neuroendocrinology

authors： Giorgi RR,Correa-Giannella ML,Casarini AP,Machado MC,Bronstein MD,Cescato VA,Giannella-Neto D

更新日期：2005-01-01 00:00:00

abstract：:The hypothesis was tested that corticotropin-releasing factor (CRF) is involved in the inhibition of gonadotropin secretion during chronic hyperprolactinemia. Two models of hyperprolactinemia were used, namely inoculation with the prolactin (PRL)-secreting tumor 7315b and implantation of isogenic pituitary glands. Gon...

journal_title：Neuroendocrinology

authors： Kooy A,de Greef WJ,Vreeburg JT,Hackeng WH,Ooms MP,Lamberts SW,Weber RF

更新日期：1990-03-01 00:00:00

abstract：:Studies were undertaken to characterize the secretion of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) into the hypophysial-portal circulation of the conscious sheep. In addition, we examined the temporal relationship between the secretion of these two hypothalamic peptides and the secretion of t...

journal_title：Neuroendocrinology

authors： Engler D,Pham T,Fullerton MJ,Ooi G,Funder JW,Clarke IJ

更新日期：1989-04-01 00:00:00

abstract：:The relationship between the growth hormone/insulin-like growth factor (GH-IGF)-I status and memory performance is studied in 24 elderly males and females, aged 75-85 years. Positron emission tomography (PET) was used to measure differences in regional cerebral blood flow during the performance of a delayed-non-match-...

journal_title：Neuroendocrinology

authors： Arwert LI,Veltman DJ,Deijen JB,Lammertsma AA,Jonker C,Drent ML

更新日期：2005-01-01 00:00:00

abstract：:Histamine (HA) stimulates the release of the pro-opiomelanocortin (POMC)-derived peptides ACTH, beta-endorphin (beta-END), beta-lipotropin and alpha-melanocyte-stimulating hormone, and HA is involved in the mediation of the stress-induced release of these peptides. The effect of HA is indirect and may involve the hypo...

journal_title：Neuroendocrinology

authors： Kjaer A,Knigge U,Bach FW,Warberg J

更新日期：1992-09-01 00:00:00

abstract：:Chronic exposure to Delta(9)-tetrahydrocannabinol (Delta(9)-THC) increases corticotropin-releasing hormone (CRH) and proopiomelanocortin (POMC) gene expression in the rat hypothalamus. The levels of circulating gonadal steroids concurrently modulate both neuropeptides in male and female rats. However, it remains unkno...

journal_title：Neuroendocrinology

authors： Corchero J,Manzanares J,Fuentes JA

更新日期：2001-09-01 00:00:00

abstract：:Neonatal rats exhibit a period of diminished pituitary and adrenocortical responses to stress during the first 2 weeks of life. Since thyroid hormones are known to affect brain development, modulation of these responses to stress by alterations in thyroid hormone status have been investigated in hypothyroid (Hypo) and...

journal_title：Neuroendocrinology

authors： Walker CD,Sizonenko PC,Aubert ML

更新日期：1989-09-01 00:00:00

abstract：:Although glutamate is the predominant excitatory amino acid in the vertebrate central nervous system (CNS) where it affects a variety of physiological processes and pathophysiological states, the role that glutamate receptors may play outside the CNS has not been clearly established. In the present study, the effects ...

journal_title：Neuroendocrinology

authors： Giovannucci DR,Stuenkel EL

更新日期：1995-08-01 00:00:00

abstract：:In the present study we utilized the 7315a PRL- and ACTH-secreting tumor to induce a hyperprolactinemic (HP) state sufficient to profoundly suppress the postcastration LH rise in female rats. Tumor-induced prolactin levels which ranged 2,000-3,000 ng/ml substantially reduced the LH rise in both ovariectomized (OVX) an...

journal_title：Neuroendocrinology

authors： Shu C,Selmanoff M

更新日期：1991-09-01 00:00:00

abstract：:Immunoreactive thyroid-stimulating hormone (IR-TSH) has been detected in the hypothalamus and is released in vitro by a calcium-dependent mechanism when the tissue is depolarized. Recently, immunocytochemical studies have revealed that IR-TSH is present in thyrotropes in the pars tuberalis. Therefore, because these th...

journal_title：Neuroendocrinology

authors： De Vito WJ,Connors JM,Hedge GA

更新日期：1985-07-01 00:00:00

abstract：:A patch-clamp study was conducted on cultured frog pituitary melanotrophs, in order to investigate the effects of adrenaline on the electrical activity of these cells. In the whole-cell configuration, adrenaline (1 microM) caused hyperpolarization that was accompanied by a fall in membrane input resistance and a block...

journal_title：Neuroendocrinology

authors： Valentijn JA,Vaudry H,Cazin L

更新日期：1994-01-01 00:00:00

abstract：:To study the role of the hypothalamus in the regulation of growth hormone (GH) synthesis, the rate of amino acid incorporation into GH in vitro was examined in rats with anterolateral deafferentation of the medial basal hypothalamus. Amino acid incorporation into GH (GH synthesis) decreased significantly 7 days after ...

journal_title：Neuroendocrinology

authors： Ieiri T,Ishikawa K,Suzuki M,Shimoda S

更新日期：1988-05-01 00:00:00

abstract：:Dexras1, a newly identified member of the Ras superfamily of proteins, was discovered in AtT-20 corticotrope cells because its expression was induced in response to glucocorticoids (dexamethasone; Dex). As yet, the function of Dexras1 is unknown, but its rapid induction in response to glucocorticoids suggests the poss...

journal_title：Neuroendocrinology

authors： Brogan MD,Behrend EN,Kemppainen RJ

更新日期：2001-10-01 00:00:00

abstract：:In these three experiments, we investigated the effect of adrenalectomy and adrenal demedullation on the stress-induced impairment of long-term potentiation (LTP) in the rat hippocampal slice. In the first, adrenalectomy alone resulted in a significant reduction in LTP, while exposure to stress resulted in a further r...

journal_title：Neuroendocrinology

authors： Shors TJ,Levine S,Thompson RF

更新日期：1990-01-01 00:00:00

abstract：:The effects of intracerebroventricularly (i.c.v.) injected interleukin-1 beta (IL-1 beta: 1, 2.5, 10, and 25 ng) were studied on plasma growth hormone (GH) and prolactin (PRL) concentrations in freely moving rats chronically implanted with i.c.v. cannulas and intracardial catheters. Significant changes in PRL secretio...

journal_title：Neuroendocrinology

authors： Payne LC,Obal F Jr,Opp MR,Krueger JM

更新日期：1992-07-01 00:00:00

abstract：:The acute effects of hypothalamic electrical stimulation on the secretion of FSH and LH have been examined in anestrous and estrous ferrets. Basal levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were higher in the anestrous than in the estrous animals; the anestrous animals showed a more mark...

journal_title：Neuroendocrinology

authors： Donovan BT,ter Haar MB

更新日期：1977-01-01 00:00:00

abstract：:We have previously reported that luteinizing hormone releasing hormone (LH-RH) levels in the medial basal hypothalamus (MBH) of adult male rats castrated for 2 weeks can be raised by testosterone (T) or estradiol (E2) treatment for 3-4 days. The present study was undertaken to determine the time after castration when ...

journal_title：Neuroendocrinology

authors： Kalra PS

更新日期：1985-09-01 00:00:00

abstract：:The neurohypophysial peptide hormone [Arg8]vasopressin (AVP) has well documented pressor effects in the periphery. These are mediated by vasopressin receptors (VPRs) of the V1a subtype, expressed by vascular smooth muscle cells, which induce vascular contraction when activated. AVP also has effects on the vasculature ...

journal_title：Neuroendocrinology

authors： Sermasi E,Howl J,Pyner S,Wheatley M,Coote JH

更新日期：1995-12-01 00:00:00

abstract：:This study was carried out to clarify the central effects of neuropeptide Y (NPY) on gonadotropin and prolactin (PRL) release in the male rat and to evaluate the hypothesis that it may play a role in negative feedback regulation of gonadotropin secretion in the male. NPY (4 micrograms in 2 microliters 0.9% NaCl) or an...

journal_title：Neuroendocrinology

authors： Reznikov AG,McCann SM

更新日期：1993-06-01 00:00:00

abstract：:Dopaminergic agonists are effective in vivo in inhibiting lactotrope proliferation and prolactin (PRL)-secreting pituitary tumors. The purpose of the present study was to demonstrate in vitro actions of dopaminergic agents on proliferation and cell shape of rat lactotropes. Anterior pituitary cells cultured with serum...

journal_title：Neuroendocrinology

authors： Arita J,Hashi A,Hoshi K,Mazawa S,Suzuki S

更新日期：1998-09-01 00:00:00

abstract：:Using a high-performance liquid chromatography (HPLC) system coupled with an electrochemical detector, the concentrations of dopamine (DA) and 5-hydroxytryptamine (5-HT) and their major specific metabolites 3,4-dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindole-3-acetic acid (5-HIAA), respectively, were measured i...

journal_title：Neuroendocrinology

authors： Kerdelhué B,Bojda F,Lesieur P,Pasqualini C,el Abed A,Lenoir V,Douillet P,Chiueh MC,Palkovits M

更新日期：1989-02-01 00:00:00

abstract：:Anterior pituitaries from female Sprague-Dawley rats (160-200 g b.w) bearing electrolytic lesions of the median eminence were qualitatively and quantitatively investigated by electron microscopy and the findings compared with those from intact animals or sham-operated controls. This study was performed in basal condit...

journal_title：Neuroendocrinology

authors： Rossi GL,Probst D,Panerai AE,Cocchi D,Locatelli V,Müller EE

更新日期：1979-01-01 00:00:00

abstract：:Multiple unit activity (MUA) was recorded from the adrenocorticotropic area (n. posterior medialis hypothalami, PMH) of unrestrained resting pigeons throughout the 24 h period and compared with plasma corticosterone levels (B). Bilateral electrolytic lesions of the hippocampus suppressed diurnal variations of MUA and ...

journal_title：Neuroendocrinology

authors： Bouillé C,Baylé JD

更新日期：1978-01-01 00:00:00

abstract：:The effect of pinealectomy or immunization against melatonin (Mel) and N-acetylserotonin (NAS) on plasma prolactin (Prl) levels was studied in rats following pineal stimulation induced by blinding or exposure to short photoperiods (1 h light and 23 h darkness daily). Blinding alone or together with pinealectomy or imm...

journal_title：Neuroendocrinology

authors： Niles LP,Brown GM,Grota LJ

更新日期：1977-01-01 00:00:00

abstract：:The purpose of this study was to determine the effect of rendering newborn male Sprague-Dawley rats hypothyroid with 131I on development of the hypothalamic-pituitary axis. Hormonal responses to thyrotropin-releasing hormone (TRH), haloperidol (H), and luteinizing hormone-releasing hormone (LHRH) were determined at 9,...

journal_title：Neuroendocrinology

authors： Sowers JR,Resch G,Walker S,Sollars E

更新日期：1980-05-01 00:00:00

abstract：:We used an in vivo pharmacological approach to investigate the potential influence of serotonin (5-HT) on peptide release from the intermediate lobe (IL) of the rat pituitary. Plasma levels of alpha-melanocyte-stimulating hormone (alpha-MSH) as well as the ultrastructural appearance of IL cells were used as indicators...

journal_title：Neuroendocrinology

authors： Carr JA,Saland LC,Samora A,Benavidez S,Krobert K

更新日期：1991-12-01 00:00:00

abstract：:The hypothalamic neurons containing substance P (SP) were examined immunohistochemically in rats with a normal estrous cycle or persistent estrus (PE), in pregnancy and in lactating state. In PE animals, the neurons increased in number 1 week after ovariectomy, but then decreased and disappeared. During pregnancy, the...

journal_title：Neuroendocrinology

authors： Tsuruo Y,Hisano S,Nakanishi J,Katoh S,Daikoku S

更新日期：1987-05-01 00:00:00

abstract：:Introduction Dysregulation of the mTORC1-dependent pathways in pancreatic neuroendocrine neoplasms (PanNENs) underlies the introduction of the mTORC1 inhibitor everolimus as treatment of advanced progressive PanNENs. Although everolimus significantly increases progression free survival, most patients acquire secondary...

journal_title：Neuroendocrinology

authors： Terracciano F,Capone A,Montori A,Rinzivillo M,Partelli S,Panzuto F,Pilozzi E,Arcidiacono PG,Sette C,Capurso G

更新日期：2020-07-02 00:00:00

abstract：:Pregnancy and parturition are associated with opioid-mediated elevations in maternal pain thresholds. This analgesia is subserved by a spinal cord dynorphin/kappa-opiate receptor system. During gestation, elevated pain thresholds are paralleled by a significant increase in the content of dynorphin (1-17 and 1-8) in th...

journal_title：Neuroendocrinology

authors： Medina VM,Dawson-Basoa ME,Gintzler AR

更新日期：1993-09-01 00:00:00

abstract：:The expression of the alpha-subunit of the glycoprotein hormones was studied in the developing rat pituitary by in situ hybridization and immunocytochemical techniques. The alpha-subunit mRNA labelling was detected in Rathke's pouch at 12 days' gestation (E12); at E13, it was exclusively concentrated in the pars tuber...

journal_title：Neuroendocrinology

authors： Stoeckel ME,Hindelang C,Klein MJ,Poissonnier M,Félix JM

更新日期：1993-12-01 00:00:00