Abstract：
:A sensitive and specific radioimmunoassay for substance P has been developed and its full characterisation is described. The assay was used to investigate the stability of substance P in tissue in order to establish the optimal conditions of tissue storage for maximal recovery of the peptide. The results indicate unexpected post-mortem changes in tissue substance P content and suggests its existence in at least two separate pools, which differ in their susceptibility to degradation. These results highlight the need for careful consideration of both extraction technique and assay characteristics in radioimmunological investigations of substance P.
journal_name
Life Scijournal_title
Life sciencesauthors
McGregor GP,Bloom SRdoi
10.1016/0024-3205(83)90211-4subject
Has Abstractpub_date
1983-02-07 00:00:00pages
655-62issue
6eissn
0024-3205issn
1879-0631pii
0024-3205(83)90211-4journal_volume
32pub_type
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