Two distinct TL-like molecular subsets defined by monoclonal antibodies on the surface of human thymocytes with different expression on leukemia lines.

Abstract:

:Monoclonal antibodies reacting with TL-like class I antigens expressed on the surface of human thymocytes and some T leukemia lines were found to define three independent epitopic clusters, two of which could be shown to reside on serologically distinct molecular subsets by a solid-phase radioimmunoassay as well as by sequential immunoprecipitation. Both molecular subsets consist of a 49-K heavy chain associated with a beta-2 microglobulin light chain. Thymocytes expressed similar amounts of the two molecular subsets, while on T leukemia lines the amount of these two molecular subsets varied from line to line.

journal_name

Immunogenetics

journal_title

Immunogenetics

authors

Olive D,Dubreuil P,Mawas C

doi

10.1007/BF00364207

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

253-64

issue

3

eissn

0093-7711

issn

1432-1211

journal_volume

20

pub_type

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