Abstract:
:The association between histo-compatibility antigens and disease is reviewed, in particular that between HLA-B27 and spondylitic disorders, i.e., ankylosing spondylitis, Reiter's arthritis, psoriatic arthritis, and ankylosing hyperostosis. We determined whether the presence of HLA-B27 predicted specific radiographic findings and, conversely, whether specific radiographic changes predicted antigenic status. The prevalences of the HLA-B27 antigen in our patients were: ankylosing spondylitis, 100%; Reiter's arthritis, 93%; psoriatic arthritis, 55%; and ankylosing hyperostosis, 12%. The only specific radiographic finding associated with B27 positivity was severe spondylitis in psoriasis.
journal_name
Radiologyjournal_title
Radiologyauthors
Schumacher TM,Genant HK,Kellet MJ,Mall JC,Fye KHdoi
10.1148/126.2.289subject
Has Abstractpub_date
1978-02-01 00:00:00pages
289-97issue
2eissn
0033-8419issn
1527-1315journal_volume
126pub_type
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