HLA-B27 associated arthropathies.

Abstract:

:The association between histo-compatibility antigens and disease is reviewed, in particular that between HLA-B27 and spondylitic disorders, i.e., ankylosing spondylitis, Reiter's arthritis, psoriatic arthritis, and ankylosing hyperostosis. We determined whether the presence of HLA-B27 predicted specific radiographic findings and, conversely, whether specific radiographic changes predicted antigenic status. The prevalences of the HLA-B27 antigen in our patients were: ankylosing spondylitis, 100%; Reiter's arthritis, 93%; psoriatic arthritis, 55%; and ankylosing hyperostosis, 12%. The only specific radiographic finding associated with B27 positivity was severe spondylitis in psoriasis.

journal_name

Radiology

journal_title

Radiology

authors

Schumacher TM,Genant HK,Kellet MJ,Mall JC,Fye KH

doi

10.1148/126.2.289

subject

Has Abstract

pub_date

1978-02-01 00:00:00

pages

289-97

issue

2

eissn

0033-8419

issn

1527-1315

journal_volume

126

pub_type

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