Aspects of parietal cell biology: cells and vesicles.

abstract：:Neuroendocrine tumors are very heterogeneous, develop from a variety of tissues, and can be difficult to diagnose. Without the clinical manifestation of metastases, it is often difficult to characterize them as malignant. Even so-called completely (R0) resected tumors can spread clinically visible metastases within a ...

journal_title：Annals of the New York Academy of Sciences

authors： Koch CA,Gimm O,Vortmeyer AO,Al-Ali HK,Lamesch P,Ott R,Kluge R,Bierbach U,Tannapfel A

更新日期：2006-08-01 00:00:00

abstract：:The discrepancy between dynamical mass measures of objects such as galaxies and the observed distribution of luminous matter in the universe is typically explained by invoking an unseen "dark matter" component. Dark matter must necessarily be nonbaryonic. We introduce a simple hypothesis to do away with the necessity ...

journal_title：Annals of the New York Academy of Sciences

authors： Kinney WH,Brisudova M

更新日期：2001-06-01 00:00:00

abstract：:Adherent-cell-depleted primed rabbit splenocytes were capable of mounting an in vitro response to SRBC. The addition of alveolar macrophages (AM) to adherent-cell-depleted or unseparated lymphoid cell populations resulted in significant suppression of the PFC response. Suppressive activity was limited to AM and depend...

journal_title：Annals of the New York Academy of Sciences

authors： Herscowitz HB,Pennline KJ,Conrad RE,Ullrich SE,Gerber HR

更新日期：1979-01-01 00:00:00

abstract：:While there has been substantial growth in early childhood development (ECD) services in low- and middle-income countries (LMICs), there is considerable inequity in their distribution and quality. Evidence-based governance strategies are necessary, but currently they are insufficient for widespread, quality implementa...

journal_title：Annals of the New York Academy of Sciences

authors： Britto PR,Yoshikawa H,van Ravens J,Ponguta LA,Reyes M,Oh S,Dimaya R,Nieto AM,Seder R

更新日期：2014-01-01 00:00:00

abstract：:Coccidioidomycosis is a potentially serious fungal infection contracted in endemic areas of the desert southwestern United States. Limited information exists about its incidence and clinical course in patients with rheumatic diseases, who may be at higher risk of symptomatic or disseminated coccidioidomycosis because ...

journal_title：Annals of the New York Academy of Sciences

authors： Mertz LE,Blair JE

更新日期：2007-09-01 00:00:00

abstract：:Monitoring of wildlife diseases started in Scandinavia as sporadic postmortem examinations in the early 20th century. In 1945 a monitoring program for wildlife health was initiated. The program is today an integrated part of the National Environmental Monitoring programs in Sweden. The total material today comprises m...

journal_title：Annals of the New York Academy of Sciences

authors： Morner T

更新日期：2002-10-01 00:00:00

abstract：:Relaxin (RLX) has antifibrotic effects in a number of tissues. Many of these effects are similar to those induced by the activators of peroxisome proliferator-activated receptor gamma (PPARgamma), raising the possibility that a mechanism for RLX's antifibrotic effects may involve activation of the PPARgamma pathway. T...

journal_title：Annals of the New York Academy of Sciences

authors： Singh S,Bennett RG

更新日期：2009-04-01 00:00:00

abstract：:Hydrogen sulfide (H2 S) is a highly neurotoxic gas. Acute exposure can lead to neurological sequelae among survivors. A drug for treating neurological sequelae in survivors of acute H2 S intoxication is needed. Using a novel mouse model we evaluated the efficacy of cobinamide (Cob) for increasing survival of, and redu...

journal_title：Annals of the New York Academy of Sciences

authors： Anantharam P,Whitley EM,Mahama B,Kim DS,Sarkar S,Santana C,Chan A,Kanthasamy AG,Kanthasamy A,Boss GR,Rumbeiha WK

更新日期：2017-11-01 00:00:00

abstract：:Older age is associated with functional declines throughout the body, including some aspects of cognitive performance. While dementia develops in only some elderly individuals, declines in cognitive functioning have an impact on daily living for many others. There are individual differences in age-related cognitive ch...

journal_title：Annals of the New York Academy of Sciences

authors： Moffat SD

更新日期：2005-12-01 00:00:00

abstract：:Jopock (Jpk), a transacting factor associated with the position-specific regulatory element of murine Hoxa-7, has shown to induce cell death in both prokaryotic and eukaryotic cells when introduced and overexpressed. Since Jpk protein harbors a transmembrane domain (TM) and a putative endoplasmic reticulum (ER) -reten...

journal_title：Annals of the New York Academy of Sciences

authors： Kim HS,Kong KA,Chung H,Park S,Kim MH

更新日期：2007-01-01 00:00:00

abstract：:In the inflammatory synovium production of collagenase is probably responsible for the degradation of collagen in the extracellular matrix and distortion of the architecture and function of the joints. Major collagenase-producing cells are mesenchymal cells such as fibroblasts and chondrocytes, which synthesize and se...

journal_title：Annals of the New York Academy of Sciences

authors： Krane SM,Conca W,Stephenson ML,Amento EP,Goldring MB

更新日期：1990-01-01 00:00:00

abstract：:Fibronectin is a ubiquitous extracellular matrix (ECM) protein known to play a critical role in cell adhesion. In the present study we dissected the effects of glucocorticoids and cyclic adenosine 3',5'-monophosphate (cAMP) on FN expression in cultures of cytotrophoblasts isolated from human term placentas to identify...

journal_title：Annals of the New York Academy of Sciences

authors： Guller S,Wozniak R,Leibman MI,Lockwood CJ

更新日期：1994-09-30 00:00:00

abstract：:Factors which modify the relationship between body temperature and skin blood flow during exercise in heat were studied. Direct measurement of right atrial pressure during exercise in heat showed that the leveling off of forearm blood flow took place when blood temperature exceeded 38 degrees C and central venous pres...

journal_title：Annals of the New York Academy of Sciences

authors： Nagashima K,Yoshida T,Nose H,Takamata A,Morimoto T

更新日期：1997-03-15 00:00:00

abstract：:The purpose of this study was to test the anticancer properties of the water-insoluble derivative of camptothecin, 9-nitrocamptothecin (9NC), administered in a liposome formulation (L-9NC) in aerosol to mice with subcutaneous xenografts of three human cancers and in mice with murine melanoma and human osteosarcoma pul...

journal_title：Annals of the New York Academy of Sciences

authors： Knight V,Kleinerman ES,Waldrep JC,Giovanella BC,Gilbert BE,Koshkina NV

更新日期：2000-01-01 00:00:00

abstract：:1. There are several endogenous ligands that bind to I-receptors of both the I1 and I2 subclass. These include: (a) classic CDS, a partially purified entity isolated by the criteria that it displaces binding ligands to alpha 2- and I-receptors; (b) immunoreactive (ir)-CDS, a moiety that binds to antibodies raised agai...

journal_title：Annals of the New York Academy of Sciences

authors： Reis DJ,Li G,Regunathan S

更新日期：1995-07-12 00:00:00

abstract：:Whole body exposure of rabbits to microwave radiation causes a decrease in ascorbic acid in the lens. In our study, rabbit lenses maintained in culture medium (37 degrees C) were exposed to either pulsed or continuous wave S-band radiation for 10-15 min at power densities between 0 and 200 mW/cm-2. Total ascorbic acid...

journal_title：Annals of the New York Academy of Sciences

authors： Weiter JJ,Finch ED,Schulz W,Frattali V

更新日期：1975-02-28 00:00:00

abstract：:Endometriosis is a complex gynecologic disorder that has long been recognized as showing heritable tendencies, with recurrence risks of 5-7% for first-degree relatives. Familial and epidemiologic studies support that this disease is a genetic disorder of polygenic/multifactorial inheritance. The current investigationa...

journal_title：Annals of the New York Academy of Sciences

authors： Bischoff F,Simpson JL

更新日期：2004-12-01 00:00:00

abstract：:This paper examines the frequency of CIND, the profile of early cognitive deficits in stroke patients, the differences in the profile of cognitive impairment in people with CIND and those with vascular dementia, and the MRI associations of CIND in older stroke patients. ...

journal_title：Annals of the New York Academy of Sciences

authors： Ballard C,Stephens S,McLaren A,Wesnes K,Kenny RA,Burton E,O'Brien J,Kalaria R

更新日期：2002-11-01 00:00:00

abstract：:The involvement of the c-Myc transcription factor in neoplastic transformation is well documented. However, which of its numerous target genes are crucial for tumorigenesis remains a frequently contested issue. We have recently established a non-transgenic murine model for B-cell lymphoma based on neoplastic conversio...

journal_title：Annals of the New York Academy of Sciences

authors： Yu D,Cozma D,Park A,Thomas-Tikhonenko A

更新日期：2005-11-01 00:00:00

abstract：:Patients with vascular dementia are frequently encountered in Japan reaching nearly 50% of those with senile dementia, which is equal to or even slightly higher than patients with Alzheimer's disease. This contrasts with a much lower ratio of patients with vascular dementia in the United States. The majority of vascul...

journal_title：Annals of the New York Academy of Sciences

authors： Yanagihara T

更新日期：2002-11-01 00:00:00

abstract：:Nuclear receptors are transcription factors that are activated by ligands and subsequently bind to regulatory regions in target genes, thereby modulating their expression. Nuclear receptors thus allow the organism to integrate signals coming from the environment and to adapt by modifying the expression levels of relev...

journal_title：Annals of the New York Academy of Sciences

authors： Bocher V,Pineda-Torra I,Fruchart JC,Staels B

更新日期：2002-06-01 00:00:00

abstract：:Little is known about how mitogenic factors generate growth regulatory signals and how these are mediated within the cell. We have developed three different types of mitogenic stimuli in order to identify the possible existence of common denominators in a complex and perhaps pleiotypic signal-response system. 3T3 cell...

journal_title：Annals of the New York Academy of Sciences

authors： Zetterberg A,Engström W,Larsson O

更新日期：1982-12-10 00:00:00

abstract：:Significant advances have been made over the past few years concerning the cellular and molecular events underlying neuron death. Recently, it is becoming increasingly clear that some of genes induced during cerebral ischemia may actually serve to rescue the cell from death. However, the injured cell may not be capabl...

journal_title：Annals of the New York Academy of Sciences

authors： Yenari MA,Dumas TC,Sapolsky RM,Steinberg GK

更新日期：2001-06-01 00:00:00

abstract：:Thymosin alpha 1, originally isolated as the compound responsible for reconstitution of immune function in thymectomized animal models, has enjoyed a wide-ranging clinical development program over the past decades, extending across multiple companies, indications, countries, and continents. This paper provides an over...

journal_title：Annals of the New York Academy of Sciences

authors： Tuthill C,Rios I,McBeath R

更新日期：2010-04-01 00:00:00

abstract：:Our studies have shown that the acyclic nucleotide analogues PMEA and HPMPC are able to penetrate into cells and are then activated to mono- and diphosphate derivatives. The latter correspond to triphosphate analogues and presumably serve an important role in the biological activity exerted by these antiviral agents. ...

journal_title：Annals of the New York Academy of Sciences

authors： Bronson JJ,Ho HT,De Boeck H,Woods K,Ghazzouli I,Martin JC,Hitchcock MJ

更新日期：1990-01-01 00:00:00

abstract：:During viewing of a near target, the gain of the visually modulated vestibulo-ocular reflex (vVOR) exceeds 1.0. We investigated whether retinal image slip contributes to this gain increase by measuring responses during strobe illumination. Subjects showed greater gain values during normal versus strobe illumination of...

journal_title：Annals of the New York Academy of Sciences

authors： Han YH,Kumar AN,Somers JT,Reschke MF,Leigh RJ

更新日期：2005-04-01 00:00:00

abstract：:Human platelets in sufficient numbers for a therapeutic transfusion can be collected for preservation either by pooling ABO- and Rh-compatible platelets or by apheresis procedures using mechanical cell-separating machines. Human platelets have been frozen successfully with 5 or 6% dimethyl sulfoxide (DMSO) and stored ...

journal_title：Annals of the New York Academy of Sciences

authors： Valeri CR

更新日期：1985-01-01 00:00:00

abstract：:In summary, the exon/intron structure of the chicken type II collagen gene is identical with that of the chicken alpha 2(I) collagen gene and differs at only one known position from the human and mouse alpha 1(I) genes. However, the chicken type II gene is different from the chicken alpha 2(I) gene in that it is consi...

journal_title：Annals of the New York Academy of Sciences

authors： Upholt WB,Strom CM,Sandell LJ

更新日期：1985-01-01 00:00:00

abstract：:Recent cross-cultural studies of child development reveal that child rearing, while strikingly culturally variable, is everywhere designed to make the child's experience of important lessons constant, to link those lessons to emotional arousal, and to connect them to evaluations of the child's goodness and badness. Th...

journal_title：Annals of the New York Academy of Sciences

authors： Quinn N

更新日期：2003-10-01 00:00:00

abstract：:Insulin-like factor 3 (INSL3), previously known as the relaxin-like factor (RLF), is a major peptide hormone secreted from the testicular Leydig cells of adult men and circulating in the blood at a concentration of approximately 1 ng/mL. Women also produce INSL3 in the theca interna cells of ovarian follicles, but cir...

journal_title：Annals of the New York Academy of Sciences

authors： Ivell R,Hartung S,Anand-Ivell R

更新日期：2005-05-01 00:00:00