Abstract:
:Quinoxalines belong to a class of excellent heterocyclic scaffolds owing to their wide biological properties and diverse therapeutic applications in medicinal research. They are complementary in shapes and charges to numerous biomolecules they interact with, thereby resulting in increased binding affinity. The pharmacokinetic properties of drugs bearing quinoxaline cores have shown them to be relatively easy to administer either as intramuscular solutions, oral capsules or rectal suppositories. This work deals with recent advances in the synthesis and pharmacological diversities of quinoxaline motifs which might pave ways for novel drugs development.
journal_name
Eur J Med Chemjournal_title
European journal of medicinal chemistryauthors
Ajani OOdoi
10.1016/j.ejmech.2014.08.034subject
Has Abstractpub_date
2014-10-06 00:00:00pages
688-715eissn
0223-5234issn
1768-3254pii
S0223-5234(14)00769-7journal_volume
85pub_type
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