Abstract:
:An investigation was made of the distribution and the ontogenesis of various types of receptors in the bladder detrusor muscles and sphincter isolated from human fetuses at different stages of pregnancy. Cholinergic receptors appear very early in the fetal urinary bladder since contractile responses to bethanechol, competitively blocked by atropine, are observed in detrusor muscle preparations at three months and in the sphincter at four months. Later on, the density of cholinergic receptors increases in the detrusor muscle whereas there is a progressive reduction in the sphincter.
journal_name
Urologyjournal_title
Urologyauthors
Mitolo-Chieppa D,Schönauer S,Grasso G,Cicinelli E,Carratú MRdoi
10.1016/0090-4295(83)90201-7subject
Has Abstractpub_date
1983-06-01 00:00:00pages
599-603issue
6eissn
0090-4295issn
1527-9995pii
0090-4295(83)90201-7journal_volume
21pub_type
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