Combined force spectroscopy, AFM and calorimetric studies to reveal the nanostructural organization of biomimetic membranes.

abstract：:The effect of peptides on bilayer----non-bilayer phase transitions can be used as a tool to investigate the molecular aspects of peptide-lipid interactions. In this contribution the action on membranes of the peptide antibiotic gramicidin A and the bee venom component melittin are compared. Although the known structur...

journal_title：Chemistry and physics of lipids

authors： Tournois H,de Kruijff B

更新日期：1991-03-01 00:00:00

abstract：:The 17-propanamide derivatives of diastereomeric Δ(14)-17α- and 17β-estradiols, the potential candidates of a 17β-hydroxysteroid dehydrogenase (17β-HSD) inhibitor, were synthesized in 11 steps from estrone. The principal reactions employed involved in (1) conversion of estrone to the corresponding Δ(14)-estrone, (2) G...

journal_title：Chemistry and physics of lipids

authors： Iida T,Ogawa S,Tamegai H,Adachi Y,Saito H,Ikegawa S,Konishi H,Takagi A,Matsuzaki T

更新日期：2011-02-01 00:00:00

abstract：:A simplified procedure for lipid digestion, well suited for handling a large number of samples, was used to analyze a variety of common phospholipids. This procedure involves digestion of phospholipids in perchloric acid at 130 degrees C with minimal sample manipulation. For all lipids tested, complete destruction, ne...

journal_title：Chemistry and physics of lipids

authors： Mrsny RJ,Volwerk JJ,Griffith OH

更新日期：1986-01-01 00:00:00

abstract：:To investigate the efficacy of reducing plasma lipoprotein(a) (Lp(a)) as well as low density lipoprotein cholesterol (LDL-C) levels on the prevention of restenosis after PTCA, LDL-apheresis was attempted on a total of 54 patients at six institutions. LDL-apheresis using a dextran sulfate cellulose column has been prov...

journal_title：Chemistry and physics of lipids

authors： Yamaguchi H,Lee YJ,Daida H,Yokoi H,Miyano H,Kanoh T,Ishiwata S,Kato K,Nishikawa H,Takatsu F

更新日期：1994-01-01 00:00:00

abstract：:The effects of Ca2+ on rotational and translational diffusion of lipids in multilamellar dimyristoylphosphatidylcholine (DMPC)-water systems were investigated by time-resolved phosphorescence anisotropy steady-state fluorescence polarization and fluorescence recovery after photobleaching (FRAP) experiments. Above the ...

journal_title：Chemistry and physics of lipids

authors： Blatt E,Vaz WL

更新日期：1986-10-01 00:00:00

abstract：:Aqueous dispersions of 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine, on cooling below the chain melting temperature, form hollow cylindrical structures known as 'tubules'. We have studied the formation of tubules in methanol/water, ethanol/water and n-propanol/water. For each alcohol, there is a defined w...

journal_title：Chemistry and physics of lipids

authors： Ratna BR,Baral-Tosh S,Kahn B,Schnur JM,Rudolph AS

更新日期：1992-11-01 00:00:00

abstract：:Applications of solid-state NMR spectroscopy for investigating the influences of lipid-cholesterol interactions on membrane fluctuations are reviewed in this paper. Emphasis is placed on understanding the energy landscapes and fluctuations at an emergent atomistic level. Solid-state (2)H NMR spectroscopy directly meas...

journal_title：Chemistry and physics of lipids

authors： Molugu TR,Brown MF

更新日期：2016-09-01 00:00:00

abstract：:A structural studies have been performed on new complex glycolipids extracted from hog gastric mucosa by 0.4 M sodium acetate in methanol-chloroform-water, and which were purified to homogeneity by DEAE-Sephadex and Florisil column chromatography and by preparative thin-layer chromatography in three solvent systems. F...

journal_title：Chemistry and physics of lipids

authors： Slomiany BL,Slomiany A

更新日期：1977-09-01 00:00:00

abstract：:Plasmalogens (1-O-1'-alkenyl-2-acylglycerophospholipids) and to a lesser extent the 1-O-alkyl analogs are ubiquitous and in some cases major constituents of mammalian cellular membranes and of anaerobic bacteria. In archaebacteria polar lipids of the cell envelope are either diphytanylglycerolipids or bipolar macrocyc...

journal_title：Chemistry and physics of lipids

authors： Paltauf F

更新日期：1994-12-01 00:00:00

abstract：:The role of the ceramide moiety of gangliosides, together with the deriving aggregative properties of ganglioside in solution, in the process of ganglioside-cell interactions was studied. The natural GM1(stearoyl) and the synthetic GM1(acetyl), containing the stearoyl and acetyl groups as the acyl moiety, respectively...

journal_title：Chemistry and physics of lipids

authors： Bassi R,Sonnino S

更新日期：1992-07-01 00:00:00

abstract：:We have investigated monomolecular fluid-like films of palmitoyl oleoylphosphatidyl lipids with choline, glycerol and serine head groups, respectively. Conventional Langmuir trough experiments have been evaluated towards a thermodynamic analysis applying a novel approach that was recently developed in this laboratory....

journal_title：Chemistry and physics of lipids

authors： Weis I,Welzel PB,Bähr G,Schwarz G

更新日期：2000-03-01 00:00:00

abstract：:Surface plasmon resonance (SPR) has become one of the most important techniques for studying macromolecular interactions. The most obvious advantages of SPR over other techniques are: direct and rapid determination of association and dissociation rates of binding process, no need for labelling of protein or lipids, an...

journal_title：Chemistry and physics of lipids

authors： Besenicar M,Macek P,Lakey JH,Anderluh G

更新日期：2006-06-01 00:00:00

abstract：:Ionic properties of didodecanoylphosphatidylglycerol (C12PG), didodecanolyphosphatidyl-l'-propanol (C12PP), di-(12-methyl, 13-methyl)-pentadecanoylphosphatidylglycerols (C15PG) and dihexadecanoylphosphatidylglycerol (C16PG) have been studied at the air-water interface using titration experiments at constant ionic stre...

journal_title：Chemistry and physics of lipids

authors： Sacré MM,Tocanne JF

更新日期：1977-04-01 00:00:00

abstract：:The quantitation of Lp(a) by immunoassay presents a major technical problem, because the molecular mass of the (a) protein of Lp(a) can vary between 419,000 and 838,000 Da (Gaubatz et al. (1990) J. Lipid Res. 31, 603-612), and this variability is determined by at least 24 alleles of the (a) gene. In an attempt to over...

journal_title：Chemistry and physics of lipids

authors： Kottke BA,Bren ND

更新日期：1994-01-01 00:00:00

abstract：:The oligosaccharide chain of glycosphingolipids (GSLs) has a marked influence on their thermotropic behavior, intermolecular packing and surface electrical potential. The transition temperature and enthalpy of GSLs decrease proportionally to the complexity of the polar head group and show a linear dependence with the ...

journal_title：Chemistry and physics of lipids

authors： Maggio B,Fidelio GD,Cumar FA,Yu RK

更新日期：1986-12-15 00:00:00

abstract：:Mycobacteria are intracellular pathogens that can invade and survive within host macrophages. Mycobacterial infections remain a major cause of mortality and morbidity worldwide, with serious concerns of emergence of multi and extensively drug-resistant tuberculosis. While significant advances have been made in identif...

journal_title：Chemistry and physics of lipids

authors： Viswanathan G,Jafurulla M,Kumar GA,Raghunand TR,Chattopadhyay A

更新日期：2018-07-01 00:00:00

abstract：:Trehalose lipids are bacterial biosurfactants which present interesting physicochemical and biological properties. These glycolipids have a number of different commercial applications and there is an increasing interest in their use as therapeutic agents. The amphiphilic nature of trehalose lipids points to the membra...

journal_title：Chemistry and physics of lipids

authors： Teruel JA,Ortiz A,Aranda FJ

更新日期：2014-07-01 00:00:00

abstract：:The interactions of iodine, iodide and triiodide with phosphatidylcholine multilayers have been investigated in order to find supporting data for conduction mechanisms of iodine-doped bimolecular lipid membranes. On the basis of order-disorder parameters it can be concluded that phospholipid multilayers interact with ...

journal_title：Chemistry and physics of lipids

authors： Loshchilova E,Karvaly B

更新日期：1977-06-01 00:00:00

abstract：:Chain-ordering/melting transition in a series of saturated diacylphosphatidylcholines (PCs) in aqueous dispersions have been studied experimentally (calorimetric and ultrasonic techniques) and theoretically (an Ising-like lattice model). The shape of the calorimetric curves was compared with the theoretical data and i...

journal_title：Chemistry and physics of lipids

authors： Kharakoz DP,Panchelyuga MS,Tiktopulo EI,Shlyapnikova EA

更新日期：2007-12-01 00:00:00

abstract：:Perturbations induced by ethylazinphos on the physical organization of dipalmitoylphosphatidylcholine (DPPC) and DPPC/cholesterol membranes were studied by differential scanning calorimetry (DSC) and fluorescence polarization of 2-, 6-, 12-(9-anthroyloxy) stearic acids and 16-(9-anthroyloxy) palmitic acid. Ethylazinph...

journal_title：Chemistry and physics of lipids

authors： Videira RA,Antunes-Madeira MC,Madeira VM

更新日期：1999-02-01 00:00:00

abstract：:The concentration of TL in Penaeus kerathurus muscle and cephalothorax was 1.03+/-0.04 (75.9+/-0.8% of which was PhL) and 2.36+/-0.07% (45.5+/-0.8% of which was PhL) of the wet tissue, respectively. The phosphatidylethanolamine represented 26.4+/-0.6% (85.6% diacyl- and 14.4% alkyl-acyl- or alkenyl-acyl-analogues) of ...

journal_title：Chemistry and physics of lipids

authors： Miniadis-Meimaroglou S,Kora L,Sinanoglou VJ

更新日期：2008-04-01 00:00:00

abstract：:A Raman spectroscopic study has been carried out on a number of cholesterols and cholesterol derivatives in the crystalline state, in order to obtaine some empirical correlations between the Raman spectra and structure of each cholesterol form. Although the Raman spectra of the various cholesterols are highly complex ...

journal_title：Chemistry and physics of lipids

authors： Faiman R

更新日期：1977-01-01 00:00:00

abstract：:Phospholipase D activity is stimulated rapidly upon occupation of cell-surface receptors. One of the intracellular regulators of phospholipase D activity has been identified as ADP ribosylation factor (ARF). ARF is a small GTP binding protein whose function has been elucidated in vesicular traffic. This review puts in...

journal_title：Chemistry and physics of lipids

authors： Cockcroft S

更新日期：1996-05-24 00:00:00

abstract：:Cardiolipin is a major phospholipid in mitochondria and is involved in the generation of cellular energy in the form of ATP. In mammalian and eukaryotic cells it is synthesized via the cytidine-5'-diphosphate-1,2-diacyl-sn-glycerol phosphate pathway. This brief review will describe some of the more recent studies on m...

journal_title：Chemistry and physics of lipids

authors： Mejia EM,Nguyen H,Hatch GM

更新日期：2014-04-01 00:00:00

abstract：:Infarcted porcine heart tissue and surrounding tissue were investigated for the content of plasmalogens and oxidatively derived corresponding alpha-hydroxyaldehydes as well as for products of lipid peroxidation, e.g. malondialdehyde, glyoxal, 2-hydroxyheptanal and oxygenated fatty acids. Oxidation products of unsatura...

journal_title：Chemistry and physics of lipids

authors： Dudda A,Spiteller G,Kobelt F

更新日期：1996-07-30 00:00:00

abstract：:2-N-(Hexadecanoyl)-amino-4-nitrophenyl phosphorylcholine-hydroxide a compound resembling sphingomyelin is synthesized. It is cleaved by sphingomyelinase to the chromogenic N-acylaminonitrophenyl moiety. Phospholipase C preparations do not hydrolyze this compound. The starting material is 2-amino-4-nitrophenol which wh...

journal_title：Chemistry and physics of lipids

authors： Gal AE,Fash FJ

更新日期：1976-02-01 00:00:00

abstract：:A study of the vibrational behavior of five saturated monoacid triacylglycerides is performed by Raman spectroscopy at room temperature in the 3100-500 cm(-1) spectral range. The splitting of the CO stretching mode leads to conclude on the existence of two or three geometries of CO in the "knot" group OCO. The CO stre...

journal_title：Chemistry and physics of lipids

authors： Bresson S,El Marssi M,Khelifa B

更新日期：2005-04-01 00:00:00

abstract：:Under condition of ROS formation in lipid membranes, free radical reactions can proceed in both hydrophobic (peroxidation of lipids, POL) and polar (free radical fragmentation) parts of the bilayer. Free-radical fragmentation is typical for the lipids containing a hydroxyl group in β-position with respect to an ester ...

journal_title：Chemistry and physics of lipids

authors： Olshyk VN,Melsitova IV,Yurkova IL

更新日期：2014-01-01 00:00:00

abstract：:DNA interactions with the bilayers of cationic liposomes were studied using a novel model experiment: DNAs were locally injected by a micropipette to a part of a giant unilamellar vesicle. The resulting phenomena were directly observed in optical microscope. Giant unilamellar vesicles (GUVs), about 100 microm in diame...

journal_title：Chemistry and physics of lipids

authors： Angelova MI,Tsoneva I

更新日期：1999-08-01 00:00:00

abstract：:Despite immense progress in our comprehension of lipase structure and function during the past decade, the basis for lipase acyl specificities has remained poorly understood. This review summarizes some recent advances in the understanding at the molecular-level of substrate acyl recognition by two members in a group ...

journal_title：Chemistry and physics of lipids

authors： Holmquist M

更新日期：1998-06-01 00:00:00