Abstract：
:Chromosomal aberrations in bone marrow and lymph node cells have been investigated in 47 patients with lymphogranulomatosis 24--72 hr after administration of a single therapeutic dose of cyclophosphan and natulan. It is shown that the injurious action of cyclophosphan and natulan lasts more than 72 hr. An analysis of the dynamics of various types of chromosomal aberrations testifies that cyclophosphan and natulan affect cellular constituents found in the synthetic or post-synthetic phases of the cell cycle.
journal_name
Neoplasmajournal_title
Neoplasmaauthors
Neistadt EL,Gershanovich ML,Kolygin BA,Ogorodnikova BN,Fedoreev GA,Chekharina EA,Filov VAsubject
Has Abstractpub_date
1978-01-01 00:00:00pages
91-4issue
1eissn
0028-2685issn
1338-4317journal_volume
25pub_type
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