Abstract:
:In this issue of Blood, Lu et al describe the cooperation between an orally bioavailable mouse double minute 2 (MDM2) antagonist (RG7112) and the pegylated interferon α (Peg-IFNα 2a) to target JAK2V617F hematopoietic progenitors and stem cells. Their work provides a rationale for the treatment of patients suffering from myeloproliferative neoplasms (MPNs).
journal_name
Bloodjournal_title
Bloodauthors
Plo Idoi
10.1182/blood-2014-06-579623subject
Has Abstractpub_date
2014-07-31 00:00:00pages
668-9issue
5eissn
0006-4971issn
1528-0020pii
124/5/668journal_volume
124pub_type
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