Spectral analysis of Doppler flow velocity signals: assessment of objectives, methods, and interpretation.

abstract：:Optoelectronic plethysmography (OEP) is a noninvasive method for assessing lung volume variations and the contributions of different anatomical compartments of the chest wall (CW) through measurements of the motion of markers attached to the CW surface. The present study proposes a new method for analyzing the local C...

journal_title：Annals of biomedical engineering

authors： Solav D,Meric H,Rubin MB,Pradon D,Lofaso F,Wolf A

更新日期：2017-08-01 00:00:00

abstract：:The field of percutaneous coronary intervention has witnessed many progressions over the last few decades, more recently with the advancement of fully degradable bioabsorbable stents. Bioabsorbable materials, such as metallic alloys and aliphatic polyesters, have the potential to yield stents which provide temporary s...

journal_title：Annals of biomedical engineering

authors： Boland EL,Shine R,Kelly N,Sweeney CA,McHugh PE

更新日期：2016-02-01 00:00:00

abstract：:A computer-based feedback system has been developed to adjust the concentration of oxygen in the inspired gas of a patient under artificial respiration. The system uses a proportional plus integral controller and feedback of arterial oxygen saturation to adjust the inspired oxygen fraction. The effectiveness of the co...

journal_title：Annals of biomedical engineering

authors： Tehrani FT

更新日期：1992-01-01 00:00:00

abstract：:The current paradigm in tissue engineering is that "full regeneration" or "total replacement" of normal tissue is required in order to restore joint function. However, there is considerable evidence that suggests that targets other than "normality" may actually be required for tissue substitutes. Sometimes "less than ...

journal_title：Annals of biomedical engineering

authors： Frank CB,Shrive NG,Boorman RS,Lo IK,Hart DA

更新日期：2004-03-01 00:00:00

abstract：:Long-range dependency has been found in most rhythmic motor signals. The origin of this property is unknown and largely debated. There is a controversy on the influence of voluntary control induced by requiring a pre-determined pace such as asking subjects to step to a metronome. We studied the cycle duration variabil...

journal_title：Annals of biomedical engineering

authors： Warlop TB,Bollens B,Crevecoeur F,Detrembleur C,Lejeune TM

更新日期：2013-08-01 00:00:00

abstract：:Lung cancer patients often suffer from severe airway stenosis, the symptoms of which can be relieved by the implantation of stents. Different respiratory stents are commercially available, but the impact of their mechanical performance on tissue responses is not well understood. Two novel laser-cut and hand-braided ni...

journal_title：Annals of biomedical engineering

authors： Thiebes AL,McGrath DJ,Kelly N,Sweeney CA,Kurtenbach K,Gesché VN,Clauser J,O'Brien B,Bruzzi M,McHugh PE,Jockenhoevel S,Cornelissen CG

更新日期：2019-08-01 00:00:00

abstract：:Continuous flow left ventricular devices (CF-LVADs) support the failing heart at a constant speed and alters the loads on the aortic valve. This may cause insufficiency in the aortic valve under long-term CF-LVAD support. The aim of this study is to assess the aortic valve function under varying speed CF-LVAD support....

journal_title：Annals of biomedical engineering

authors： Bozkurt S,van de Vosse FN,Rutten MC

更新日期：2015-08-01 00:00:00

abstract：:Defining the constituent regulatory molecules in tendon is critical to understanding the process of tendon repair and instructive to the development of novel treatment modalities. The purpose of this study is to define the structural, expressional, and mechanical changes in the tendon injury response, and elucidate th...

journal_title：Annals of biomedical engineering

authors： Dunkman AA,Buckley MR,Mienaltowski MJ,Adams SM,Thomas SJ,Satchell L,Kumar A,Pathmanathan L,Beason DP,Iozzo RV,Birk DE,Soslowsky LJ

更新日期：2014-03-01 00:00:00

abstract：:The study was to explore the effects of BMP-2 gene modified canine bone marrow stromal cells (bMSCs) mediated by a nonviral PEI derivative (GenEscort™ II) in promoting bone formation in vitro and in vivo. Canine bMSCs were cultured and transfected with plasmids containing bone morphogenetic protein-2 gene (pBMP-2) or ...

journal_title：Annals of biomedical engineering

authors： Lü K,Zeng D,Zhang Y,Xia L,Xu L,Kaplan DL,Jiang X,Zhang F

更新日期：2011-06-01 00:00:00

abstract：:Development of increasingly complex integrated cellular systems will be a major challenge for the next decade and beyond, as we apply the knowledge gained from the sub-disciplines of regenerative medicine, synthetic biology, micro-fabrication and nanotechnology, systems biology, and developmental biology. In this pros...

journal_title：Annals of biomedical engineering

authors： Kamm RD,Bashir R

更新日期：2014-02-01 00:00:00

abstract：:A number of human head finite element (FE) models have been developed from different research groups over the years to study the mechanisms of traumatic brain injury. These models can vary substantially in model features and parameters, making it important to evaluate whether simulation results from one model are read...

journal_title：Annals of biomedical engineering

authors： Ji S,Ghadyani H,Bolander RP,Beckwith JG,Ford JC,McAllister TW,Flashman LA,Paulsen KD,Ernstrom K,Jain S,Raman R,Zhang L,Greenwald RM

更新日期：2014-01-01 00:00:00

abstract：:This study is aimed at refining our understanding of the role of vortex formation at mitral mechanical heart valve (MHV) closure and its association with the high intensity transient signals (HITS) seen in echocardiographic studies with MHV recipients. Previously reported numerical results described a twofold process ...

journal_title：Annals of biomedical engineering

authors： Rambod E,Beizai M,Sahn DJ,Gharib M

更新日期：2007-07-01 00:00:00

abstract：:To better understand oxygen utilization by the retina, a mathematical model of oxygen diffusion and consumption in the cat outer, avascular retina was developed by analyzing previously recorded profiles of oxygen tension (PO2) as a function of retinal depth. Simple diffusion modelling of the oxygen distribution throug...

journal_title：Annals of biomedical engineering

authors： Haugh LM,Linsenmeier RA,Goldstick TK

更新日期：1990-01-01 00:00:00

abstract：:This paper reviews the applications of accelerometers on the detection of physiological acoustic signals such as heart sounds, respiratory sounds, and gastrointestinal sounds. These acoustic signals contain a rich reservoir of vital physiological and pathological information. Accelerometer-based systems enable continu...

journal_title：Annals of biomedical engineering

authors： Hu Y,Kim EG,Cao G,Liu S,Xu Y

更新日期：2014-11-01 00:00:00

abstract：:A lumped parameter compartmental model for the nonsteady flow of the cerebrovascular fluid is constructed. The model assumes constant resistances that relate fluid flux to pressure gradients, and compliances between compartments that relate fluid accumulation to rate of pressure changes. Resistances are evaluated by u...

journal_title：Annals of biomedical engineering

authors： Sorek S,Bear J,Karni Z

更新日期：1989-01-01 00:00:00

abstract：:We have developed a method for quantifying the complexity of activation patterns observed during ventricular fibrillation (VF) that is based on our previously reported methodology for decomposing epicardial mapping data into a set of isolated wavefronts. One-half second datasets are acquired from a 21 x 24 array of un...

journal_title：Annals of biomedical engineering

authors： Rogers JM,Usui M,KenKnight BH,Ideker RE,Smith WM

更新日期：1997-09-01 00:00:00

abstract：:We and others have shown that changing surface characteristics of the spacer implanted during the first Masquelet stage alters some aspects of membrane development. Previously we demonstrated that titanium (TI) spacers create membranes that are better barriers to movement of solutes > 70 kDa in size than polymethyl me...

journal_title：Annals of biomedical engineering

authors： Toth Z,Roi M,Evans E,Watson JT,Nicolaou D,McBride-Gagyi S

更新日期：2019-01-01 00:00:00

abstract：:While viscoelastic responses of isolated trunk soft tissues have been characterized in earlier studies, the effects of external loading and flexion rate on these responses in the intact human trunk are largely unknown. Two experiments were conducted to measure trunk viscoelastic behaviors, one involving prolonged flex...

journal_title：Annals of biomedical engineering

authors： Toosizadeh N,Nussbaum MA

更新日期：2013-06-01 00:00:00

abstract：:The traditional auscultatory technique and current methodologies for measuring human blood pressure are limited when used in situations where extreme vibration or acoustic noise is present. In this study, human subjects were used to establish the effectiveness of a novel adaptive blood pressure monitoring (ABPM) syste...

journal_title：Annals of biomedical engineering

authors： Pinto L,Dhanantwari A,Wong W,Stergiopoulos S,Maris M

更新日期：2002-05-01 00:00:00

abstract：:Currently, autologous cartilage provides the gold standard for auricular reconstruction. However, synthetic biomaterials offer a number of advantages for ear reconstruction including decreased donor site morbidity and earlier surgery. Critical to implant success is the material's mechanical properties as this affects ...

journal_title：Annals of biomedical engineering

authors： Griffin MF,Premakumar Y,Seifalian AM,Szarko M,Butler PE

更新日期：2016-12-01 00:00:00

abstract：:The design and operating characteristics of the first self-contained in-the-ear device to deliver altered auditory feedback is described for applications with those who stutter. The device incorporates a microdigital signal processor core that reproduces the high fidelity of unaided listening and auditory self-monitor...

journal_title：Annals of biomedical engineering

authors： Stuart A,Xia S,Jiang Y,Jiang T,Kalinowski J,Rastatter MP

更新日期：2003-02-01 00:00:00

abstract：:In the past decades, vascular tissue engineering has made great strides towards bringing engineered vascular tissues to the clinics and, in parallel, obtaining in-lab tools for basic research. Herein, we propose the design of a novel dual-mode bioreactor, useful for the fabrication (construct mode) and in vitro stimul...

journal_title：Annals of biomedical engineering

authors： Bono N,Meghezi S,Soncini M,Piola M,Mantovani D,Fiore GB

更新日期：2017-06-01 00:00:00

abstract：:The signal that governs the chemotactic response of mammalian white blood cells and tissue cells arises from membrane-localized binding events involving chemotactic factor ligands and receptors and G proteins. Fluctuations in this signal have been traditionally attributed to significant "noise" in receptor-ligand bind...

journal_title：Annals of biomedical engineering

authors： Moghe PV,Tranquillo RT

更新日期：1995-05-01 00:00:00

abstract：:We present an optical non-contact method for heart beat monitoring, based on the measurement of chest wall movements induced by the pumping action of the heart, which is eligible as a surrogate of electrocardiogram (ECG) in assessing both cardiac rate and heart rate variability (HRV). The method is based on the optica...

journal_title：Annals of biomedical engineering

authors： Morbiducci U,Scalise L,De Melis M,Grigioni M

更新日期：2007-01-01 00:00:00

abstract：:Organ models are used for planning and simulation of operations, developing new surgical instruments, and training purposes. There is a substantial demand for in vitro organ phantoms, especially in urological surgery. Animal models and existing simulator systems poorly mimic the detailed morphology and the physical pr...

journal_title：Annals of biomedical engineering

authors： Adams F,Qiu T,Mark A,Fritz B,Kramer L,Schlager D,Wetterauer U,Miernik A,Fischer P

更新日期：2017-04-01 00:00:00

abstract：:Recently, we reported that tethering and rolling of neutrophils in shear flow over a substrate of E-selectin signals activation of beta 2-integrins and firm adhesion via an intracellular signaling pathway involving phosphorylation of p38 MAP kinase. In the current study the objective was to examine the molecular mecha...

journal_title：Annals of biomedical engineering

authors： Hentzen E,McDonough D,McIntire L,Smith CW,Goldsmith HL,Simon SI

更新日期：2002-09-01 00:00:00

abstract：:Opportunities to provide clinical immersion experiences to bioengineering undergraduate students have expanded over the last several years. These programs allow students to observe the clinical environment in order to better understand workflow processes, the context in which medical equipment is used, and identify un...

journal_title：Annals of biomedical engineering

authors： Kotche M,Felder AE,Wilkens K,Stirling S

更新日期：2020-09-01 00:00:00

abstract：:User preferences need to be taken into account in order to be able to design devices that will gain acceptance both in a clinical and home setting. Sensor systems become redundant if patients or clinicians do not want to work with them. The aim of this systematic review was to determine both patients' and clinicians' ...

journal_title：Annals of biomedical engineering

authors： Bergmann JH,McGregor AH

更新日期：2011-09-01 00:00:00

abstract：:The toxic or therapeutic effect of an inhaled aerosol is highly dependent upon the site and extent of deposition in the lung. A novel MRI-based method was used to quantify the spatial distribution of particles in the rat lung. Rats were exposed to 0.95 μm-diameter iron oxide particles in a controlled manner (N = 6) or...

journal_title：Annals of biomedical engineering

authors： Oakes JM,Scadeng M,Breen EC,Prisk GK,Darquenne C

更新日期：2013-05-01 00:00:00

abstract：:The nose is the front line defender of the respiratory system. Unsteady simulations in three-dimensional models have been developed to study transport patterns in the human nose and its overall air-conditioning capacity. The results suggested that the healthy nose can efficiently provide about 90% of the heat and the ...

journal_title：Annals of biomedical engineering

authors： Naftali S,Rosenfeld M,Wolf M,Elad D

更新日期：2005-04-01 00:00:00