Tumor heterogeneity has important consequences for personalized medicine in ovarian cancer.

abstract：:This report presents preliminary observations on the distribution of an epithelial surface antigen in human trophoblastic cells studied with the monoclonal antibody Ber-EP4 by means of an immunoperoxidase technique. Three cases of gestational choriocarcinoma and 20 cases of both villous and extravillous trophoblast, i...

journal_title：Histology and histopathology

authors： Babury RA,Moscovic EA

更新日期：1993-04-01 00:00:00

abstract：:Our study aimed to investigate the association of Pyruvate Kinase isozyme type M2 (PKM2) with radiation resistance in locally advanced cervical squamous cell carcinoma (LACSCC). We retrospectively reviewed 132 female patients who received primary radiation therapy to treat LACSCC at Federation Internationale of Gyneco...

journal_title：Histology and histopathology

authors： Zhao Y,Shen L,Chen X,Qian Y,Zhou Q,Wang Y,Li K,Liu M,Zhang S,Huang X

更新日期：2015-11-01 00:00:00

abstract：:Studies in a canine bronchogenic carcinoma model indicate that alveolar type II cells may differentiate from carcinogen-exposed epithelium of larger bronchi and generate adenocarcinomas with bronchioloalveolar and other growth patterns. In this study, we investigated whether type II cells are one of the major prolifer...

journal_title：Histology and histopathology

authors： Ten Have-Opbroek AA,Benfield JR,van Krieken JH,Dijkman JH

更新日期：1997-04-01 00:00:00

abstract：:In order to reveal modulation of the number of pulmonary neuroendocrine cells (PNEC) in interstitial lung diseases and to clarify significance of cell proliferation activity in occurrence of PNEC, we counted airway PNEC of the patients of idiopathic interstitial pneumonia, secondary interstitial pneumonia and control ...

journal_title：Histology and histopathology

authors： Ito T,Ogura T,Ogawa N,Udaka N,Hayashi H,Inayama Y,Yazawa T,Kitamura H

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:Describe the morphological changes that take place in the lung parenchyma and in the airways during the respiratory cycle with a view to establishing a relationship between them. SUBJECTS:Adult Wistar rats. INTERVENTIONS:The lungs were fixed at seven different points in the respiratory cycle: Inflation, 10 ...

journal_title：Histology and histopathology

authors： Escolar JD,Escolar MA,Blasco J,Ros LH

更新日期：2007-01-01 00:00:00

abstract：:The S100 gene family, which is composed of at least 24 members carrying the Ca2+ binding EF-hand motif, has been implicated in both intracellular and extracellular functions, including enzyme activities, immune responses, cytoskeleton dynamics, Ca2+ homeostasis, cell growth and cell differentiation. Altered S100 prote...

journal_title：Histology and histopathology

authors： Yao R,Davidson DD,Lopez-Beltran A,MacLennan GT,Montironi R,Cheng L

更新日期：2007-09-01 00:00:00

abstract：:An ultrastructural and histological study was made to analyse the structural and cellular features of the pulmonary lesions produced in Wistar rats by intraperitoneal (i.p.) administration of cyclophosphamide (two i.p. doses of 150 mg CP/1 kg bw/1 ml PBS). Rats exposed to cyclophosphamide (CP) developed a condition wh...

journal_title：Histology and histopathology

authors： Sulkowski S,Sulkowska M

更新日期：1999-10-01 00:00:00

abstract：:Bone marrow features in stable-phase chronic myelogenous leukemia (CML) are characterized by a striking heterogeneity which is determinable by appropriate means including representative pre-treatment trephine biopsies, immunohistochemistry and morphometry. Cell lineages involved to a variable extent consist not only o...

journal_title：Histology and histopathology

authors： Thiele J,Kvasnicka HM,Fischer R

更新日期：1999-10-01 00:00:00

abstract：:There is scarce information on the possible effects of chronic exposure to mercury on skeletal muscle. Dental personnel are frequently exposed to inhalation of metallic mercury vapours. The skeletal muscle of five technicians and one dentist (females, age 36-55) was studied. All of them presented symptoms of chronic m...

journal_title：Histology and histopathology

authors： Nadorfy-López E,Torres SH,Finol H,Méndez M,Bello B

更新日期：2000-07-01 00:00:00

abstract：:TNFalpha exerts apoptosis throughout an intracellular transduction pathway that involves the kinase proteins TRAF-2 (integration point of apoptotic and survival signals), ASK1 (pro-apoptotic protein), MEK-4 (p38 activator and metastasis suppressor gene), JNK (stress mitogen activated protein kinase) and the transcript...

journal_title：Histology and histopathology

authors： Royuela M,Rodríguez-Berriguete G,Fraile B,Paniagua R

更新日期：2008-10-01 00:00:00

abstract：:The acute and chronic effects of bombesin (BM) on the structure and function of rat adrenal cortex were investigated by morphometric and radioimmunological techniques. An intraperitoneal bolus injection of 2 micrograms/rat BM markedly raised plasma corticosterone (B) concentration (PBC). The intraperitoneal BM infusio...

journal_title：Histology and histopathology

authors： Malendowicz LK,Nussdorfer GG,Miskowiak B,Majchrzak M

更新日期：1995-01-01 00:00:00

abstract：:In Duchenne muscular dystrophy (DMD), the progressive loss of muscle and its ability to function is associated with significant fibrosis, representing the major disease complication in patients. Halofuginone, a halogenated analog of the naturally occurring febrifugine, has been shown to prevent fibrosis in various ani...

journal_title：Histology and histopathology

authors： Wellner G,Mordechay S,Evans P,Genin O,Pines M,Halevy O

更新日期：2019-07-01 00:00:00

abstract：:Emperipolesis has recently been described as a constant feature of "biphasic squamoid" papillary renal cell carcinoma (BPRCC). We also noticed this in some high-grade (HG) RCC, which promoted the present study to estimate the incidence of emperipolesis in RCCs and to describe them in further detail. 14 cases of HGRCC ...

journal_title：Histology and histopathology

authors： Rotterova P,Martinek P,Alaghehbandan R,Prochazkova K,Damjanov I,Rogala J,Suster S,Perez-Montiel D,Alvarado-Cabrero I,Sperga M,Svajdler M,Michalova K,Pivovarcikova K,Daum O,Hora M,Dusek M,Ondic O,Stehlikova A,Michal M

更新日期：2018-03-01 00:00:00

abstract：:Recent evidence has shown that vascular function depends not only on cells within the vessels, but is also significantly modulated by circulating cells derived from the bone marrow. A number of studies indicate that an early reendothelialization by circulating endothelial precursors after vascular injury prevents exce...

journal_title：Histology and histopathology

authors： Forte A,Cipollaro M,Cascino A,Galderisi U

更新日期：2007-05-01 00:00:00

abstract：:Neutrophil extracellular traps (NETs) are innate immune systems against invading pathogens. NETs are characterized as released DNA mixed with cytoplasmic antimicrobial proteins such as myeloperoxidase, proteinase3 and neutrophil elastase. While NETs are thought to have an important role in host defense, recent work ha...

journal_title：Histology and histopathology

authors： Nakazawa D,Kumar S,Desai J,Anders HJ

更新日期：2017-03-01 00:00:00

abstract：:Sixty male Wistar rats were used for this experiment and assigned at random to the control group or to the stimulation method. Control rats show cerebral asymmetry with right bias at the frontal and occipital lobes. In the case of stimulated rats the differences from the occipital zone increase while those from the fr...

journal_title：Histology and histopathology

authors： Isasa Chueca JA,Lahoz Gimeno M,Redondo Marco JA

更新日期：1992-07-01 00:00:00

abstract：:The salamanderfish, Lepidogalaxias salamandroides (Galaxiidae, Teleostei) is endemic to southwestern Australia and inhabits shallow, freshwater pools which evaporate during the hot summer months. Burrowing into the substrate in response to falling water levels allows these fish to aestivate for extended periods of tim...

journal_title：Histology and histopathology

authors： Collin SP,Collin HB

更新日期：1998-10-01 00:00:00

abstract：:Tumor angiogenesis plays important roles in the pathogenesis and prognosis of lung cancer. Both vascular endothelial growth factor (VEGF) and Dll4/Notch pathways are critical for angiogenesis, whereas their relationship under hypoxia in lung cancer remains unknown. Thus, in the present study, we evaluated the expressi...

journal_title：Histology and histopathology

authors： Yu S,Sun J,Zhang J,Xu X,Li H,Shan B,Tian T,Wang H,Ma D,Ji C

更新日期：2013-02-01 00:00:00

abstract：:The presence of Cajal-Retzius cells in the adult human prefrontal and visual cortices has been demonstrated with calcium binding protein immunocytochemistry and NADPH-diaphorase histochemistry. These cells expressed parvalbumin, calbindin and calretinin calcium binding proteins and displayed NADPH-diaphorase enzyme ac...

journal_title：Histology and histopathology

authors： Martín R,Gutiérrez A,Peñafiel A,Marín-Padilla M,de la Calle A

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Synaptotagmin 7 (SYT7) is a component of the synaptotagmin family, which is essential in many physiological and pathological processes. In this study, we aimed to investigate the role of SYT7 in osteosarcoma. METHODS:We defined the expression levels of SYT7 in osteosarcoma tissues and para-sarcoma tissues b...

journal_title：Histology and histopathology

authors： Wu Z,Sun Z,Huang R,Zang D,Wang C,Yan X,Yan W

更新日期：2020-03-01 00:00:00

abstract：:We wanted to examine the effect of antigen retrieval on epoxy sections where the tissue had been infiltrated by resin containing moderately increased amounts of accelerator. The concentration of accelerator DMP-30 (Tri(Dimethyl Amino Methyl) Phenol) was varied in the range of 0% to 4% in the infiltration step of the t...

journal_title：Histology and histopathology

authors： Brorson SH,Andersen T,Haug S,Kristiansen I,Risstubben A,Tchou H,Ulstein J

更新日期：1999-01-01 00:00:00

abstract：:Leukemias, a heterogeneous group of hematological disorders, are characterized by ineffective hematopoiesis and morphologic abnormalities of hematopoietic cells. Thrombocytopenia is a common problem among leukemia types that can lead to hemorrhagic complications in patients. The purpose of this review article is to id...

journal_title：Histology and histopathology

authors： Shahrabi S,Behzad MM,Jaseb K,Saki N

更新日期：2018-09-01 00:00:00

abstract：:Since endometriosis is a proliferative disease we evaluated the presence of anti-apoptotic factor (Bcl-2) and pro-apoptotic factor (Bax) in deep pelvic endometriosis. A Cross-sectional observational study was performed at Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil. Forty women aged 26 to 46 years with ...

journal_title：Histology and histopathology

authors： Abdalla Ribeiro HS,Galvāo MA,Aoki T,Aldrighi JM,Ribeiro PA

更新日期：2014-09-01 00:00:00

abstract：:To determine the appropriate time for bone reconstruction after irradiation, the healing process after autogenous iliac bone transplantation in the irradiated parietal bone was examined by scanning electron microscopy and light microscopy. Bone transplantation was carried out at the second and the fourth weeks after C...

journal_title：Histology and histopathology

authors： Takekawa M,Matsuda M,Ohotubo S

更新日期：2000-01-01 00:00:00

abstract：:Morphological and biochemical alterations have been described in neurons of the aged human brain. However, the cell death process associated with neuronal senescence remains to be elucidated. Apoptosis and autophagic degeneration, two modes of programmed cell death described in embryogenesis and tissue renewal in adul...

journal_title：Histology and histopathology

authors： Anglade P,Vyas S,Hirsch EC,Agid Y

更新日期：1997-07-01 00:00:00

abstract：:Chorioamnionitis and preeclampsia account for the majority of preterm births worldwide. Thus far, adequate methods for early detection or prevention of these diseases are lacking. In preeclampsia, accelerated villous maturation is believed to compensate placental insufficiency. However, little is known about the effec...

journal_title：Histology and histopathology

authors： Vangrieken P,Vanterpool SF,van Schooten FJ,Al-Nasiry S,Andriessen P,Degreef E,Alfer J,Kramer BW,von Rango U

更新日期：2020-08-01 00:00:00

abstract：:Chronic lung allograft dysfunction (CLAD) still remains a major drawback in the outcome following lung transplantation (LTx). New therapeutic strategies are warranted. Growth factors and their receptors like platelet-derived growth factor-receptor (PDGFR) and vascular endothelial growth factor-receptor (VEGFR), may pl...

journal_title：Histology and histopathology

authors： Keil L,Schaub AL,Hirt SW,Schmid C,Lehle K,von Suesskind-Schwendi M

更新日期：2019-07-01 00:00:00

abstract：:In the cutaneous nerves, unmyelinated nerve fibers outnumber the myelinated ones but are scarcely analyzed, especially at autopsy. This indifference toward the pathology of unmyelinated nerve fibers may be due to the necessity of electron microscopic analyses and, more importantly, the obscurity of pathological altera...

journal_title：Histology and histopathology

authors： Kanda T

更新日期：2000-01-01 00:00:00

abstract：:The epicardium is the outer mesothelial layer of the heart. It covers the myocardium and plays important roles in both heart development and regeneration. It is derived from the proepicardium (PE), groups of cells that emerges at early developmental stages from the dorsal pericardial layer (DP) close to the atrio-vent...

journal_title：Histology and histopathology

authors： Andrés-Delgado L,Galardi-Castilla M,Mercader N,Santamaría L

更新日期：2020-09-01 00:00:00

abstract：AIMS:Gastric hyperplastic polyps (GHPs) are the most common polypoid lesion of the stomach, and their malignant potential has been demonstrated. In the present study, we evaluated the mucin phenotypes of GHPs and investigated the relationships among mucin phenotypes and clinical-pathological factors, proliferative acti...

journal_title：Histology and histopathology

authors： Li J,Wu LH,Shi Y,Li HM,Song MY,Jiao YF

更新日期：2014-03-01 00:00:00