Effect of piracetam plus choline treatment on hippocampal rhythmic slow activity (RSA) and behavior in rabbits.

Abstract:

:The effects of chronic treatment with piracetam (100 mg/Kg) plus choline (100 mg/Kg) on rabbits' hippocampal electrical activity and behavior have been studied. Animals were exposed to a neutral environment, in the absence of any external stimulus, and then to an object and a stuffed sparrow-hawk. Results show a drug related reduction in the amount of the hippocampal rhythmic slow activity (RSA) and an increase in RSA high frequency values in the presence of the object and of the stuffed animal, but not in the neutral environment. This would suggest that piracetam plus choline treatment has an effect on RSA in situations in which selective attention is required.

journal_name

Life Sci

journal_title

Life sciences

authors

Fontani G,Grazzi F,Meucci M

doi

10.1016/0024-3205(84)90189-9

subject

Has Abstract

pub_date

1984-09-10 00:00:00

pages

1183-9

issue

11

eissn

0024-3205

issn

1879-0631

pii

0024-3205(84)90189-9

journal_volume

35

pub_type

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