Tetracycline and its derivatives strongly bind to and are released from the tooth surface in active form.

Abstract:

:Several antibiotics were found to adsorb to saliva-coated enamel and to inhibit in vitro plaque formation by pure cultures of oral bacteria: Actinomyces viscosus, Actinomyces naeslundii and Streptococcus mutans. Tetracycline, minocycline and oxytetracycline adsorbed to the greatest degree, showing 100-fold higher adsorption than spiramycin, the test antibiotics with least adsorption. Inhibition of in vitro plaque formation was found to require both drug substantivity (capacity for adsorption) and antimicrobial activity. Inhibition of plaque formation in the in vitro assay employed correlated well with clinical efficacy.

journal_name

J Periodontol

authors

Baker PJ,Evans RT,Coburn RA,Genco RJ

doi

10.1902/jop.1983.54.10.580

subject

Has Abstract

pub_date

1983-10-01 00:00:00

pages

580-5

issue

10

eissn

0022-3492

issn

1943-3670

journal_volume

54

pub_type

杂志文章
  • Current status of lasers in soft tissue dental surgery.

    abstract::The aims of this paper are to briefly describe laser physics, the types of lasers currently available for use on soft tissues focusing primarily on CO2 and Nd:YAG laser energies, the histological effects of lasers on oral tissues, laser safety, the clinical applications of lasers on oral soft tissues, and future direc...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1902/jop.1993.64.7.589

    authors: Pick RM,Colvard MD

    更新日期:1993-07-01 00:00:00

  • Myofascial pain dysfunction syndrome involving tumor metastasis. Case report.

    abstract::This report is an example of tumor metastasis to the temporomandibular joint and its effect on pain, restriction of jaw movement, and the subsequent inability of the patient to function normally. Neoplasm is not the usual etiology of myofascial pain dysfunctionsyndrome and the muscle sparm component of this patient's ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1975.46.5.309

    authors: Butler JH

    更新日期:1975-05-01 00:00:00

  • Clinical oral medicine. An exciting facet of postdoctoral periodontic training.

    abstract::This paper briefly reviews the historical relationship between oral medicine and periodontics. The reasons for including structured clinical oral medicine in a postdoctoral program in periodontics are discussed. Problems and solutions to such an integrated program are outlined. Guidelines for broadening the base of th...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1986.57.7.426

    authors: Hurt WC

    更新日期:1986-07-01 00:00:00

  • Evaluation of MicroRNA-146a and Its Targets in Gingival Tissues of Patients With Chronic Periodontitis.

    abstract:BACKGROUND:MicroRNAs (miRNAs) are a group of small non-coding RNAs that play an important role in the regulation of gene expression. miRNA-146a (miR-146a), a member of the miR-146 family, is involved in the control of inflammation. Periodontitis is a set of chronic inflammatory disorders of the tissues surrounding the ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2015.150319

    authors: Motedayyen H,Ghotloo S,Saffari M,Sattari M,Amid R

    更新日期:2015-12-01 00:00:00

  • Calcium hydroxide and potassium nitrate as desensitizing agents for hypersensitive root surfaces.

    abstract::The purpose of this investigation was to evaluate calcium hydroxide and potassium nitrate individually as densensitizing agents for hypersensitive root surfaces. The apparatus used in the experiment to measure hypersensitivity was (a) a thermo-electric stimulating device to measure hot and cold stimulation quantitativ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1977.48.10.667

    authors: Green BL,Green ML,McFall WT Jr

    更新日期:1977-10-01 00:00:00

  • Crestal bone changes around titanium implants. A histometric evaluation of unloaded non-submerged and submerged implants in the canine mandible.

    abstract:BACKGROUND:Today, implants are placed using both non-submerged and submerged approaches, and in 1- and 2-piece configurations. Previous work has demonstrated that peri-implant crestal bone reactions differ radiographically under such conditions and are dependent on a rough/smooth implant border in 1-piece implants and ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2000.71.9.1412

    authors: Hermann JS,Buser D,Schenk RK,Cochran DL

    更新日期:2000-09-01 00:00:00

  • A systematic review of the use of growth factors in human periodontal regeneration.

    abstract:BACKGROUND:There is a large body of evidence using cells and animal models demonstrating the effectiveness of growth factors in periodontal regeneration. However, there appears to be minimal literature comparing the efficacy of growth factors in human periodontal regeneration compared to other techniques and procedures...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1902/jop.2012.120145

    authors: Darby IB,Morris KH

    更新日期:2013-04-01 00:00:00

  • Impact of cannabis sativa (marijuana) smoke on alveolar bone loss: a histometric study in rats.

    abstract:BACKGROUND:Cannabis sativa (marijuana) can interfere with bone physiopathology because of its effect on osteoblast and osteoclast activity. However, its impact on periodontal tissues is still controversial. The present study evaluates whether marijuana smoke affects bone loss (BL) on ligature-induced periodontitis in r...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2011.100362

    authors: Nogueira-Filho GR,Todescan S,Shah A,Rosa BT,Tunes Uda R,Cesar Neto JB

    更新日期:2011-11-01 00:00:00

  • Aggregatibacter actinomycetemcomitans-Induced AIM2 Inflammasome Activation Is Suppressed by Xylitol in Differentiated THP-1 Macrophages.

    abstract:BACKGROUND:Aggressive periodontitis is characterized by rapid destruction of periodontal tissue caused by Aggregatibacter actinomycetemcomitans. Interleukin (IL)-1β is a proinflammatory cytokine, and its production is tightly regulated by inflammasome activation. Xylitol, an anticaries agent, is anti-inflammatory, but ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2016.150477

    authors: Kim S,Park MH,Song YR,Na HS,Chung J

    更新日期:2016-06-01 00:00:00

  • Early-onset periodontitis associated with Weary-Kindler syndrome: a case report.

    abstract::Weary-Kindler syndrome is a rare and poorly understood genetic disorder that has manifestations of both epidermolysis bullosa and poikiloderma congenitale. There are approximately 70 cases documented in the past 40 years but no cases appear in the dental literature, although dental findings have been discussed superfi...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1996.67.10.1004

    authors: Wiebe CB,Silver JG,Larjava HS

    更新日期:1996-10-01 00:00:00

  • Association of plasma 25-hydroxyvitamin d concentrations and pathogenic oral bacteria in postmenopausal females.

    abstract:BACKGROUND:Previous findings of an association between 25-hydroxyvitamin D [25(OH)D] concentrations and periodontal disease may be partially explained by the antimicrobial properties of vitamin D. To the best of the authors' knowledge, no study has investigated the association between 25(OH)D and pathogenic oral bacter...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2013.130518

    authors: Sahli MW,Wactawski-Wende J,Ram PK,LaMonte MJ,Hovey KM,Genco RJ,Andrews CA,Millen AE

    更新日期:2014-07-01 00:00:00

  • Hard and soft tissue evaluation of titanium dental implants and abutments with nanotubes in canines.

    abstract:BACKGROUND:Little is known regarding the interaction of dental implant surface nanotubes and oral soft and hard tissues. The purpose of this study was to evaluate both histologically and radiographically the qualitative and quantitative effects of dental implant surface nanotubes on hard and soft tissue in a canine mod...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.18-0205

    authors: Garrett PW,Johnston GW,Bosshardt DD,Jones AA,Sasada Y,Ong JL,Cochran DL

    更新日期:2020-04-01 00:00:00

  • Analysis of site specific periodontal bacteria sampling schemes.

    abstract::A great deal of controversy has existed in the periodontal literature as to whether the site or the subject should be the unit of analysis. Using the site as the unit of analysis assumes that observations of sites within the same subject are independent and ignores between subject variation. The purpose of this report...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1992.63.6.507

    authors: Gunsolley JC,Chinchilli VN,Savitt ED,Killoy W,Darack AP,Christersson LA,Fransson CF,Dunford RG,Zambon JJ

    更新日期:1992-06-01 00:00:00

  • Reliability of partial-mouth recording systems to determine periodontal status: a pilot study in an adult Portuguese population.

    abstract:BACKGROUND:The efficacy of various partial-mouth recording (PMR) systems is analyzed in the evaluation of periodontal status, using index teeth and different combinations of quadrants. METHODS:The study group was formed of 108 adults aged 25 to 65 years old. A full-mouth examination (FME) was performed in all particip...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2013.130389

    authors: Relvas M,Tomás I,Salazar F,Velazco C,Blanco J,Diz P

    更新日期:2014-06-01 00:00:00

  • Differential effects of amelogenin on mineralization of cementoblasts and periodontal ligament cells.

    abstract:BACKGROUND:Amelogenin is a major component of developing extracellular enamel matrix proteins and plays a crucial role during the formation of tooth enamel. In addition, amelogenins are suggested to exert biologic functions as signaling molecules through cell-surface receptors. The purpose of this study is to examine t...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2011.110408

    authors: Tanimoto K,Kunimatsu R,Tanne Y,Huang YC,Michida M,Yoshimi Y,Miyauchi M,Takata T,Tanne K

    更新日期:2012-05-01 00:00:00

  • Periodontal findings in diabetic and nondiabetic patients.

    abstract::This study was conducted to determine the possible influence of diabetes on the pathogenesis of periodontal disease. A total of 148 patients, 120 females and 28 males, were surveyed. Their ages ranged between 9 and 50 years, with an average age of 30. The experimental group consisted of 83 diabetics and there was a co...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1978.49.9.445

    authors: Sznajder N,Carraro JJ,Rugna S,Sereday M

    更新日期:1978-09-01 00:00:00

  • Clinical guidelines of the Italian Society of Periodontology for the reconstructive surgical treatment of angular bony defects in periodontal patients.

    abstract:BACKGROUND:The purpose of these clinical guidelines, commissioned by the Italian Society of Periodontology and compiled with the tools and instructions of the Appraisal of Guidelines for Research and Evaluation (AGREE) collaboration, was to determine, in terms of efficacy, complications, and patient opinions, the most ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,实务指引

    doi:10.1902/jop.2008.080266

    authors: Pagliaro U,Nieri M,Rotundo R,Cairo F,Carnevale G,Esposito M,Cortellini P,Pini-Prato G,Italian Society of Periodontology.

    更新日期:2008-12-01 00:00:00

  • Age-dependent distribution of periodontitis in two countries: Findings from NHANES 2009 to 2014 and SHIP-TREND 2008 to 2012.

    abstract:OBJECTIVE:We used epidemiologic data of clinical periodontal status from two population-based samples in two countries, United States and Germany, to examine 1) the impact of age on the relative contribution of recession and pocketing on the distribution of clinical attachment loss, and 2) whether it is feasible to def...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.17-0670

    authors: Billings M,Holtfreter B,Papapanou PN,Mitnik GL,Kocher T,Dye BA

    更新日期:2018-06-01 00:00:00

  • Individual predisposition and the intricate interplay between systemic biomarkers and periodontal risk in a general population.

    abstract:BACKGROUND:Increasing age is associated with systemic diseases as well as with periodontal diseases. We wondered whether a biological age score constructed exclusively from systemic biomarkers would reflect periodontal risk factors at baseline and tooth loss as well as periodontal outcome during 10 years follow-up. ME...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.20-0591

    authors: Meisel P,Nauck M,Kocher T

    更新日期:2020-12-14 00:00:00

  • Effects of chlorhexidine gel in a group of maintenance-care patients with poor oral hygiene.

    abstract::An intraindividual double-blind crossover study was designed in order to see if a 1% chlorhexidine gel used twice a day could substitute for ordinary toothpaste in group of maintenance-care patients with poor oral hygiene. Twenty patients from a student clinic participated, each with a long history of maintenance-care...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章

    doi:10.1902/jop.1986.57.6.364

    authors: Lie T,Enersen M

    更新日期:1986-06-01 00:00:00

  • Forty-eight-month periodontal attachment loss incidence in a population-based cohort study: role of baseline status, incident tooth loss, and specific behavioral factors.

    abstract:BACKGROUND:The objectives of this study were to: 1) test hypotheses that behavioral factors, baseline clinical status, and incident tooth loss are significantly associated with attachment loss incidence (ALI) and 2) quantify the effect of incident tooth loss on conclusions made about ALI. METHODS:The Florida Dental Ca...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2005.76.7.1161

    authors: Gilbert GH,Shelton BJ,Fisher MA

    更新日期:2005-07-01 00:00:00

  • Histochemical and immunocytochemical localization of dipeptidyl peptidases II and IV in human gingiva.

    abstract::Dipeptidyl peptidase (DPP) II and IV activities were demonstrated in unfixed cryostat sections of gingival tissue from chronic periodontitis patients using histochemistry with 2-methoxy-4-naphthylamine (MNA) substrates. In the case of DPP IV, enzyme localization was confirmed by immunocytochemistry with mouse monoclon...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1996.67.9.846

    authors: Kennett CN,Cox SW,Eley BM

    更新日期:1996-09-01 00:00:00

  • Effects of metronidazole plus amoxicillin in progressive untreated adult periodontitis: results of a single 1-week course after 2 and 4 months.

    abstract::A randomized, double-blind, clinical study was done to assess the microbiological and clinical effects of metronidazole plus amoxicillin (M+A) as the only therapy in 46 patients with moderate to advanced progressive adult periodontitis. Patients were included in the study after at least 2 sites showed > or =2 mm clini...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1902/jop.1998.69.11.1291

    authors: López NJ,Gamonal JA

    更新日期:1998-11-01 00:00:00

  • Irritant contact stomatitis: a review of the condition.

    abstract::Several different types of interactions are possible between a chemical, a mixture of chemicals, and associated extrinsic factors (i.e., mechanical irritation) in the oral mucosa. These interactions can be broadly classified as irritative or allergenic in nature. In each case, the pathology usually includes mucosal in...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1902/jop.1998.69.6.620

    authors: Davis CC,Squier CA,Lilly GE

    更新日期:1998-06-01 00:00:00

  • The influence of β-tricalcium phosphate blocks containing extracellular matrix on osteogenic differentiation of rat bone marrow stromal cells.

    abstract:BACKGROUND:The aim of the present study is to assess the osteogenic differentiation of rat bone marrow stromal cells (RBMCs) in β-tricalcium phosphate (β-TCP) blocks containing extracellular matrix (ECM) produced by human alveolar bone periosteal cells (HABPCs). METHODS:HABPCs were cultured in β-TCP blocks for 1 week ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2012.120490

    authors: Iwasaki K,Munemasa N,Tago K,Nemoto K,Tsujigami H,Sugaya A,Deguchi S

    更新日期:2013-10-01 00:00:00

  • Value of antibiotic prophylaxis in periodontal surgery.

    abstract::THE MORBIDITY and incidence of bacteremia in periodontal surgery with or without cephalexin prophylaxis were assessed in adults on the basis of clinical evaluations and blood cultures. Cephalexin reduced the incidence of polymicrobic bacteremias. There was no correlation between objective signs of tissue healing and a...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1982.53.5.319

    authors: Appleman MD,Sutter VL,Sims TN

    更新日期:1982-05-01 00:00:00

  • The rotation flap for covering denuded root surfaces - a closed wound technique.

    abstract::A rotation flap for covering denuded single root surfaces with attached gingiva has been described and illustrated. This was performed utilizing a closed wound technique. The single flap provided attached gingiva coverage for a moderate area while a double flap provided coverage for a larger area. Although more attach...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1977.48.1.41

    authors: Patur B

    更新日期:1977-01-01 00:00:00

  • Risk indicators for tooth loss due to periodontal disease.

    abstract:BACKGROUND:Several risk indicators for periodontal disease severity have been identified. The association of these factors with tooth loss for periodontal reasons was investigated in this cross-sectional comparative study. METHODS:All extractions performed in 21 general dental practice clinics (25% of such clinics in ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,多中心研究

    doi:10.1902/jop.2005.76.11.1910

    authors: Al-Shammari KF,Al-Khabbaz AK,Al-Ansari JM,Neiva R,Wang HL

    更新日期:2005-11-01 00:00:00

  • Microscopic, immunocytochemical, and ultrastructural properties of peri-implant mucosa in humans.

    abstract:BACKGROUND:Microscopic and immunocytochemical studies have demonstrated both similarities and differences between the gingival mucosa and the peri-implant mucosa restored around dental implants. METHODS:This study was performed on 10 samples of peri-implant mucosa from 10 patients who had undergone implant treatment 1...

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    pub_type: 杂志文章

    doi:10.1902/jop.2002.73.5.555

    authors: Marchetti C,Farina A,Cornaglia AI

    更新日期:2002-05-01 00:00:00

  • High Glucose Concentrations Suppress the Proliferation of Human Periodontal Ligament Stem Cells and Their Differentiation Into Osteoblasts.

    abstract:BACKGROUND:Diabetes mellitus (DM) is a major risk factor for periodontal disease and affects various cellular functions. Periodontal ligament stem cells (PDLSCs) play an important role in periodontal tissue regeneration; however, the effect of hyperglycemia on PDLSCs is unclear. The aim of this study is to investigate ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2015.150474

    authors: Kato H,Taguchi Y,Tominaga K,Kimura D,Yamawaki I,Noguchi M,Yamauchi N,Tamura I,Tanaka A,Umeda M

    更新日期:2016-04-01 00:00:00