Abstract:
:An H-2-restricted graft-versus-host reaction can be demonstrated when irradiated bone marrow-protected recipients receive injections of cells from radiation chimeras. The cells responsible are Thy-1-positive, thymus-dependent, radiation-sensitive and pass through a nylon wool column, i.e., they are T cells. Treatment of the cells with anti-Lyt-1 or anti-Lyt-2 serum and complement reduces but does not eliminate the activity which can be eliminated by treatment with both antisera. Combining anti-Lyt-1-treated and anti-Lyt-2-treated cells does not restore the original activity.
journal_name
Immunogeneticsjournal_title
Immunogeneticsauthors
Kindred Bdoi
10.1007/BF00364767subject
Has Abstractpub_date
1984-01-01 00:00:00pages
243-8issue
3eissn
0093-7711issn
1432-1211journal_volume
19pub_type
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