Extracranial-intracranial bypass surgery: hemodynamic and metabolic effects.

Abstract:

:After superficial temporal artery-middle cerebral artery bypass, cerebral blood flow (CBF) in the operated hemisphere increased in 6 of 17 patients. Preoperatively, the symptomatic hemisphere showed lower CBF in all six, lower oxygen metabolism in five, higher blood volume in four, and higher oxygen extraction in two. With the postoperative increase in hemispheric CBF, there was a decrease in oxygen extraction, but no change in blood volume or oxygen metabolism. In these patients, chronic regional hypoperfusion followed major vascular occlusion. Compensatory responses included dilation of intraparenchymal vessels and increased transport of oxygen from blood to tissue. These changes were partially reversed by cerebral revascularization.

journal_name

Neurology

journal_title

Neurology

authors

Powers WJ,Martin WR,Herscovitch P,Raichle ME,Grubb RL Jr

doi

10.1212/wnl.34.9.1168

subject

Has Abstract

pub_date

1984-09-01 00:00:00

pages

1168-74

issue

9

eissn

0028-3878

issn

1526-632X

journal_volume

34

pub_type

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