Prolactin suppression by serotonin antagonists in man: further evidence for serotoninergic control of prolactin secretion.

abstract：:The ability of neuropeptides to act as precursors for smaller, biologically active fragments is discussed in terms of their biotransformation. This process may involve cleavage of the parent peptide by peptidase enzymes to produce shorter polypeptides with defined biological activity, though other enzymic processes su...

journal_title：Neuroendocrinology

authors： Griffths EC,McDermott JR

更新日期：1984-12-01 00:00:00

abstract：:A reproductive facet of ghrelin, a stomach-derived orexigenic peptide involved in energy homeostasis, has been recently suggested, and predominantly inhibitory effects of ghrelin upon luteinizing hormone (LH) secretion have been demonstrated in rat models. Yet, the modulatory actions of ghrelin on the gonadotropic axi...

journal_title：Neuroendocrinology

authors： Fernández-Fernández R,Tena-Sempere M,Navarro VM,Barreiro ML,Castellano JM,Aguilar E,Pinilla L

更新日期：2005-01-01 00:00:00

abstract：:Previous studies have shown that the stimulation of LH release by the opiate receptor blocker, naloxone, can be prevented by catecholamine synthesis inhibitors, suggesting opiate regulation of catecholamine release. The present study tested whether an opiate agonist and antagonist would affect the depletion of hypotha...

journal_title：Neuroendocrinology

authors： Adler BA,Crowley WR

更新日期：1984-03-01 00:00:00

abstract：:In pituitary cells, c-fos transcription induced by releasing hormones and growth factors results from enhanced initiation of transcription, and sustained elongation of transcripts beyond the first intron. We studied the regulatory role of the first intron of the mouse c-fos gene for the control of its transcription in...

journal_title：Neuroendocrinology

authors： van Haasteren G,Li S,Ryser S,Schlegel W

更新日期：2000-12-01 00:00:00

abstract：:The effects of melatonin and an aqueous extract of bovine pineal glands on adrenal function were studied in pinealectomized, ovariectomized and hypophysectomized rats. Melatonin (50 microgram i.p., twice daily for 1 week) stimulates adrenal 5 alpha-reductase activity in intact animals and after ovariectomy. A correspo...

journal_title：Neuroendocrinology

authors： Ogle TF,Kitay JI

更新日期：1977-01-01 00:00:00

abstract：:In situ hybridization was used to examine the effects of amygdala kindling on the expression of mRNAs for mineralocorticoid receptors (MR) and glucocorticoid receptors (GR) in the rat hippocampus. Kindling increased MR mRNA levels in the dentate gyrus of the hippocampus 4 h after the last seizure, and these levels rem...

journal_title：Neuroendocrinology

authors： Clark M,Smith MA,Weiss SR,Post RM

更新日期：1994-05-01 00:00:00

abstract：:Immobilization of adult male rats resulted in concomitant, significant releases of prolactin (PRL) and oxytocin (OT). Naloxone (0.2 mg/kg, i.p.) administration 30 min prior to initiation of restraint resulted in a significant diminution of the PRL response to stress. On the other hand, a significant augmentation of OT...

journal_title：Neuroendocrinology

authors： Samson WK,McDonald JK,Lumpkin MD

更新日期：1985-01-01 00:00:00

abstract：:The sleep-wakefulness pattern and brain protein levels were determined in rats for 3 h following these conditions: administration of an inhibitor of protein synthesis (anisomycin), administration of several doses of rat growth hormone (GH) or thyrotropin, and administration of a combination of anisomycin + GH or thyro...

journal_title：Neuroendocrinology

authors： Drucker-Colín RR,Spanis CW,Hunyadi J,Sassin JF,McGaugh JL

更新日期：1975-01-01 00:00:00

abstract：:A number of neurochemical messengers have been shown to act directly on the melanotrope cells of the pars intermedia of Xenopus laevis to regulate alpha MSH secretion. In the present study the possibility that the melanotropes are also indirectly controlled has been examined. For this purpose, the characteristics of a...

journal_title：Neuroendocrinology

authors： de Koning HP,Jenks BG,Scheenen WJ,de Rijk EP,Caris RT,Roubos EW

更新日期：1991-07-01 00:00:00

abstract：:The reuptake of dopamine into nerve terminals is the primary mechanism of inactivation of this neurotransmitter in the synaptic cleft. We report sex differences and estrous cycle variations of rat striatal dopamine uptake sites. During the estrous cycle, peak density of striatal dopamine uptake sites labelled with [3H...

journal_title：Neuroendocrinology

authors： Morissette M,Di Paolo T

更新日期：1993-07-01 00:00:00

abstract：:Three control point enzymes of the Embden-Meyerhof pathway, hexokinase (HK), phosphofructokinase (PFK) and pyruvate kinase (PK) were measured by quantitative histochemical methods in individual hypothalamic nuclei of adult neonatally androgenized female rats. HK activity was significantly increased in anterior hypotha...

journal_title：Neuroendocrinology

authors： Packman PM,Bragdon MJ,Boshans RL

更新日期：1977-01-01 00:00:00

abstract：:The presence and distribution of bombesin (BBS)/gastrin-releasing peptide (GRP)-like immunoreactivity (IR) was examined in the goldfish pituitary and forebrain. BBS/GRP-like IR nerve fibres were consistently observed throughout the pituitary neurointermediate lobe (NIL); occasionally, BBS/GRP-like material was localiz...

journal_title：Neuroendocrinology

authors： Himick BA,Peter RE

更新日期：1995-04-01 00:00:00

abstract：:We have previously shown that the serotonergic regulation of renin secretion from the kidneys is mediated by a renin-releasing factor (RRF) that is present in both plasma and hypothalamus. The present studies were designed to determine the distribution of RRF in the brain and peripheral tissues and to test whether RRF...

journal_title：Neuroendocrinology

authors： Urban JH,Brownfield MS,Levine JE,Van de Kar LD

更新日期：1992-05-01 00:00:00

abstract：:The feedback effect of systemically administered dexamethasone on basal plasma corticosterone levels and on adrenocortical responses to ether plus skin incision stress were studied in intact rats and in animals with bilateral dorsal or ventral hippocampectomy or fimbria section. It was found that in rats with ventral ...

journal_title：Neuroendocrinology

authors： Feldman S,Conforti N

更新日期：1980-01-01 00:00:00

abstract：:His-dTrp-Ala-Trp-dPhe,Lys-NH2(GHRP-6) is a synthetic compound that releases GH in a dose-response and specific manner in several species and that may well be related to an endogenous compound of similar structure. The aim of this study was to investigate the in vivo GH responses to GHRP-6 in pentobarbital anesthetized...

journal_title：Neuroendocrinology

authors： Mallo F,Alvarez CV,Benitez L,Burguera B,Coya R,Casanueva FF,Dieguez C

更新日期：1993-01-01 00:00:00

abstract：:Corticotropin-releasing factor (CRF) is localized in fibers in the noradrenergic nucleus locus ceruleus (LC) and alters LC discharge characteristics when administered centrally. To determine whether CRF functions as a neurotransmitter in the LC during stress, the effects of hemodynamic stress on LC discharge were comp...

journal_title：Neuroendocrinology

authors： Valentino RJ,Wehby RG

更新日期：1988-12-01 00:00:00

abstract：:Kisspeptin is a neuropeptide that signals via a Gαq-coupled receptor, GPR54, in gonadotropin-releasing hormone (GnRH) neurons and is essential for pubertal maturation and fertility. Kisspeptin depolarizes and excites GnRH neurons primarily through the activation of canonical transient receptor potential (TRPC) channel...

journal_title：Neuroendocrinology

authors： Rønnekleiv OK,Zhang C,Bosch MA,Kelly MJ

更新日期：2015-01-01 00:00:00

abstract：:In the present study the effect of methadone (M) on gonadotropin-releasing hormone in the rat hypothalamus was investigated. The specificity of the M effect was demonstrated by injecting M (100 ng) and the M antagonist, naloxone (5 ng), into the ventromedial hypothalamus. A significant drop in the blood testosterone l...

journal_title：Neuroendocrinology

authors： Singh HH,Purohit V,Ahluwalia BS

更新日期：1982-01-01 00:00:00

abstract：:In the Djungarian hamster Phodopus sungorus, the daily temporal pattern of synthesis and release of pineal hormone melatonin, mainly the length of the period of elevated melatonin levels, may be involved in transferring the information on day length to the neuroendocrine-gonadal axis. The present study investigated th...

journal_title：Neuroendocrinology

authors： Illnerová H,Hoffmann K,Vanĕcek J

更新日期：1984-03-01 00:00:00

abstract：:The effect of steroids on the two gonadotropin-releasing hormone (GnRH) forms present in the eel (mammalian GnRH, mGnRH and chicken GnRH-II, cGnRH-II), as well as on gonadotropin (GTH), was studied using specific radioimmunoassays. Female silver eels received chronic treatments with various steroids (estradiol, testos...

journal_title：Neuroendocrinology

authors： Montero M,Le Belle N,King JA,Millar RP,Dufour S

更新日期：1995-05-01 00:00:00

abstract：:The coadministration of growth hormone (GH) secretagogues can provide insight into the neuroregulation of GH secretion. The GH response to L-dopa (125, 250 and 500 mg orally for body weights less than 15 kg, between 15 and 30 kg and greater than 30 kg, respectively), arginine (Arg; 0.5 g/kg infused intravenously over ...

journal_title：Neuroendocrinology

authors： Ghigo E,Bellone J,Imperiale E,Arvat E,Mazza E,Valetto MR,Boffano GM,Cappa M,Loche S,De Sanctis C

更新日期：1990-07-01 00:00:00

abstract：:Neurons in the adult rat ventromedial hypothalamic nucleus (VMN, 4-6 neurons per brain; 3-7 brains per group) were studied under various hormonal conditions using the single-section Golgi impregnation technique. Intact rats of both sexes and ovariectomized females treated with oil, estrogen or estrogen and progesteron...

journal_title：Neuroendocrinology

authors： Frankfurt M,Gould E,Woolley CS,McEwen BS

更新日期：1990-05-01 00:00:00

abstract：:To gain further insight into the regulation of hypothalamic TRH by thyroid hormones, we measured TRH concentration in specific hypothalamic nuclei and preproTRH mRNA levels in the anterior hypothalamus. Adult male rats were decapitated 1, 7, 14 days after thyroidectomy. Micropunches by the method of Palkovitz from sev...

journal_title：Neuroendocrinology

authors： Yamada M,Satoh T,Monden T,Murakami M,Iriuchijima T,Wilber JF,Mori M

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Manipulating thyroid hormones has been shown to influence learning and memory. Although a large body of literature is available on the effects of thyroid hormone deficiency on learning and memory functions during developmental or adult-onset hypothyroidism, electrophysiological findings are limited. This lim...

journal_title：Neuroendocrinology

authors： Taşkın E,Artis AS,Bitiktas S,Dolu N,Liman N,Süer C

更新日期：2011-01-01 00:00:00

abstract：:Gonadal steroids exert an important regulatory influence upon the biosynthetic and secretory activity of the somatostatin and growth hormone-releasing hormone (GHRH) neurons controlling the release of growth hormone. It is hypothesized that some of these effects occur in an indirect transsynaptic manner through the st...

journal_title：Neuroendocrinology

authors： Pannell C,Simonian SX,Gillies GE,Luscher B,Herbison AE

更新日期：2002-08-01 00:00:00

abstract：:Both the pituitary-adrenal axis and the pituitary-gonadal axis are under the tonic inhibitory control of endogenous opioid peptides in man. However, the precise opioid receptor involved in the modulation of these hormones remains unknown. The effect of a dose of intravenous naloxone on serum levels of luteinising horm...

journal_title：Neuroendocrinology

authors： Grossman A,Moult PJ,Cunnah D,Besser M

更新日期：1986-01-01 00:00:00

abstract：INTRODUCTION:Pituitary neuroendocrine tumors (PitNETs), the most abundant of all intracranial tumors, entail severe comorbidities. First-line therapy is transsphenoidal surgery, but subsequent pharmacological therapy is often required. Unfortunately, many patients are/become unresponsive to available drugs (somatostati...

journal_title：Neuroendocrinology

authors： Vázquez-Borrego MC,Fuentes-Fayos AC,Herrera-Martínez AD,Venegas-Moreno E,L-López F,Fanciulli A,Moreno-Moreno P,Alhambra-Expósito MR,Barrera-Martín A,Dios E,Blanco-Acevedo C,Solivera J,Granata R,Kineman RD,Gahete MD,Soto-Mor

更新日期：2020-01-01 00:00:00

abstract：:Corticotropin-releasing hormone (CRH) plays a key role in adjusting the basal and stress-activated hypothalamic-pituitary-adrenal axis (HPA). CRH is also widely distributed in extrahypothalamic circuits, where it acts as a neuroregulator to integrate the complex neuroendocrine, autonomic, and behavioral adaptive respo...

journal_title：Neuroendocrinology

authors： Bonfiglio JJ,Inda C,Refojo D,Holsboer F,Arzt E,Silberstein S

更新日期：2011-01-01 00:00:00

abstract：:Interleukin-1 (IL-1) and glucocorticoid hormones represent two key mediators involved in the modulation of the neuroimmunoendocrine response to stress. IL-1 is a potent activator of the hypothalamic-pituitary-adrenal (HPA) axis in rodents. In the immune system, glucocorticoids modulate IL-1 production and a number of ...

journal_title：Neuroendocrinology

authors： Betancur C,Lledo A,Borrell J,Guaza C

更新日期：1994-02-01 00:00:00

abstract：:Visual average evoked responses (AERs) to 4 intensities of light were studied in 5 patients with adrenal cortical insufficiency. Patients were tested off all medications, on ACTH while off all medications, and during replacement with carbohydrate-active steroids. Off treatment, when steroid levels were low, AERs were ...

journal_title：Neuroendocrinology

authors： Buchsbaum MS,Henkin RI

更新日期：1975-01-01 00:00:00