Abstract:
PURPOSE:This study aimed to examine the acute effect of caffeine on exercise capacity, exercise-related fatigue, and functional performance in prostate cancer survivors. METHODS:In this randomized, placebo-controlled, double-blind crossover study, 30 prostate cancer survivors (age, 70.3 ± 7.7 yr; body mass, 80.5 ± 13.0 kg; mean ± SD) consumed 6.04 ± 0.16 mg·kg(-1) of anhydrous caffeine or a placebo 1 h before completing a battery of exercise capacity and functional performance tests. Testing sessions were separated by 3-4 wk. Immediate fatigue and perceived exertion were measured directly pre- and postexercise at both testing sessions. RESULTS:Caffeine increased exercise capacity by 7.93 s (+3.0%; P = 0.010); however, postexercise fatigue and perception of exertion were comparable with the placebo session (P = 0.632 and P = 0.902, respectively). Increases in isometric grip strength trended toward significance in both dominant (+2.9%; P = 0.053) and nondominant (+2.1%; P = 0.061) hands in the caffeine trial compared with placebo. Caffeine ingestion did not result in improvements in performance for any of the remaining functional measures, including the timed up-and-go test, repeated chair stands, 6-m fast walk, and 6-m backward tandem walk. Systolic blood pressure and HR were significantly increased (P = 0.006 and P = 0.040, respectively) upon completion of the testing battery when compared with placebo. CONCLUSIONS:Consumption of caffeine 1 h before exercise induced improvements in exercise capacity and muscular strength in prostate cancer survivors. However, there was no change in exercise-related fatigue when compared with placebo despite reduction in timed performance of the 400-m walk. Caffeine seems to enhance exercise tolerance through improved performance with no subsequent increase in fatigue or perception of exertion and may be an appropriate strategy to promote exercise participation in prostate cancer survivors.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Cornish RS,Bolam KA,Skinner TLdoi
10.1249/MSS.0000000000000429subject
Has Abstractpub_date
2015-03-01 00:00:00pages
468-75issue
3eissn
0195-9131issn
1530-0315journal_volume
47pub_type
杂志文章,随机对照试验abstract:PURPOSE:To determine whether physical activity and fitness change in girls with and without a predisposition to obesity from 8 to 10 yr of age. METHODS:Normal-weight girls (N = 91) were recruited at 8 yr of age according to parental body mass index (BMI): LN = girls with two lean (BMI < 25 kg.m-2) parents, LNOB = girl...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000113666.98463.B0
更新日期:2004-02-01 00:00:00
abstract:PURPOSE:A decision tree based on a clinico-physiological score (SHAI score) has been developed to detect subjects susceptible to Severe High Altitude Illness (SHAI). We aimed to validate this decision tree, to rationalize the prescription of acetazolamide (ACZ) and to specify the rule for a progressive acclimatization....
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002586
更新日期:2020-12-29 00:00:00
abstract::Six adult females with normal menstrual cycles (28-31 d in length) volunteered to exercise on a bicycle ergometer on five different days of their menstrual cycles (days 2, 8, 14, 20, and 26; day 1 = onset of menstruation). Each day the subjects exercised at a maximum work load (184.4 W) and at four submaximal exercise...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::The past 10-15 yr have witnessed a rapid increase in the development of new (and not so new) statistical methods that capitalize on recent advances in high-speed computing. These computer-intensive methods are often broadly referred to as resampling techniques and take several forms depending on the specific details o...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract:PURPOSE:Overtraining is primarily related to sustained high load training, often coupled with other stressors. Studies in animal models have suggested that unremittingly heavy training (monotonous training) may increase the likelihood of developing overtraining syndrome. The purpose of this study was to extend our prel...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199807000-00023
更新日期:1998-07-01 00:00:00
abstract::By placing the muscles of the take-off leg in faster eccentric or slower concentric conditions, a high jumper can increase the ground reaction force and the height of the jump. Film analysis of seven high jumpers showed that the radial velocity of the center of mass with respect to the supporting foot was more negativ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198806000-00014
更新日期:1988-06-01 00:00:00
abstract:PURPOSE:Most studies that use either a single exercise session, exercise training, or a cross-sectional design have failed to find a relationship between exercise and plasma lipoprotein(a) [Lp(a)] concentrations. However, a few studies investigating the effects of longer and/or more strenuous exercise have shown elevat...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200109000-00014
更新日期:2001-09-01 00:00:00
abstract::The 1-mile run/walk test is the field test of choice for evaluating maximal aerobic power (VO2max) in school-aged children. The objective of this study was to determine the relative importance of selected metabolic determinants of mile run/walk performance in children 6-14 yr of age. Mile run/walk time (MRWT), VO2max,...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract:UNLABELLED:The protective effects of cardiorespiratory fitness (CRF) on hypertension (HTN) are well known; however, the association between muscular strength and incidence of HTN has yet to be examined. PURPOSE:This study evaluated the strength-HTN association with and without accounting for CRF. METHODS:Participants...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181b2f0a4
更新日期:2010-02-01 00:00:00
abstract::Ten eumenorrheic nonathletic women, aged 21-25, were studied on the 8th day following the LH peak in three consecutive cycles. Plasma level and metabolic clearance rate (MCR) of estradiol (E2) and progesterone (P) were measured before and during a 2-h continuous treadmill test at a speed corresponding to 70% of their ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract::Cyclic AMP increases in liver during exercise, the magnitude of the increase being dependent on duration and intensity of the exercise. Within limits, the increase in cAMP is closely correlated with the rate of glycogenolysis and with the exercise intensity. It is unlikely that epinephrine is involved in determining c...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1988-12-01 00:00:00
abstract:PURPOSE:This study aimed to determine whether physical activity patterns are associated with sleep later at night and if nighttime sleep is associated with physical activity patterns the next day among adult women. METHODS:Women (N = 353) living throughout the United States wore a wrist and a hip accelerometer for 7 d...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001000
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:This study aimed to examine the longitudinal associations of person-related factors with physical activity (PA) behavior in young adults. METHODS:We analyzed longitudinal self-reported time spent in moderate-intensity PA (MPA; 4-7 METs) and vigorous-intensity PA (VPA; >7 METs) from 499 young adults (49% male) ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000126
更新日期:2014-03-01 00:00:00
abstract::This 1 year study examined the effect of high impact and low impact activities on bone mineral density (BMD) at the lumbar vertebrae (L2-L4) in healthy, sedentary, early postmenopausal women. Fifteen subjects whose postmenopausal status was verified by the blood levels of follicle stimulating hormone (FSH) and estradi...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1992-11-01 00:00:00
abstract:PURPOSE:Serial evaluation of aerobic metabolism and exercise tolerance early after heart transplantation (HT). METHODS:Fifteen heart transplant recipients (HTR), aged 52.0 +/- 9.9 yr (mean +/- SD), not undergoing structured rehabilitation programs, were tested two to four times during the first 2 yr post-HT. As a refe...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000093610.71730.02
更新日期:2003-11-01 00:00:00
abstract::The purpose of this study was to describe the body composition of adolescent and young adult ballet dancers using total body electrical conductivity (TOBEC). We studied 112 female and 33 male dancers. The mean ages were 15.0 +/- 2.0 and 18.7 +/- 3.1 yr for females and males, respectively. The mean percent body fat (PB...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract:PURPOSE:Prolonged sitting time (ST) is associated with higher mortality. However, previous studies used only a single measure of ST at baseline, so they could not directly assess the effect of continued exposure to high ST, or of changes in ST, on mortality. We prospectively assessed the association of continued sedent...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3182897e87
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:To develop and provide initial psychometric support for a 16-item measure that assesses a new construct termed desire for physical competence (DPC). METHODS:A total of 157 older adults (aged 60-95) were administered the DPC along with various other questionnaires that assessed demographics, health status, soci...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000183231.61022.18
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:Concurrent and construct validity of the OMNI-Walk/Run Scale of Perceived Exertion was examined using young adult women and men (18-36 yr). METHODS:Concurrent validity was established by correlating OMNI-Walk/Run Scale ratings of perceived exertion (RPE-OMNI) with oxygen uptake (VO2), relative maximal oxygen u...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000142310.97274.94
更新日期:2004-10-01 00:00:00
abstract:PURPOSE:This study examined some physiological and performance responses to a 6-d taper, and the influence of training intensity and volume on these responses. METHODS:After 15 wk of training, 8 well-trained male middle-distance runners were randomly assigned to either a moderate volume taper (MVT, N = 4) or a low vol...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-200002000-00038
更新日期:2000-02-01 00:00:00
abstract:PURPOSE:Aerobic training (AT) and high-intensity intermittent training (HIIT) reduce arterial stiffness, whereas resistance training (RT) induces deterioration of or no change in arterial stiffness. However, the molecular mechanism of these effects of different exercise modes remains unclear. This study aimed to clarif...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000001567
更新日期:2018-06-01 00:00:00
abstract::Psychophysical scaling of symptoms or discomfort during exercise testing has evolved as an important adjunct to the study of therapeutic interventions in heart disease. One of the major shortcomings of clinical exercise testing, however, has been the assessment of chest pain. Although the presence and characteristics ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:For optimal health benefits, moderate- to vigorous-intensity physical activity (MVPA) is recommended in sustained bouts lasting ≥10 min. However, short spurts of MVPA lasting <10 min are more common in everyday life. It is unclear whether short spurts of MVPA further protect against the development of hypert...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000662
更新日期:2015-11-01 00:00:00
abstract::This study focused on age and physical activity as determinants of muscle strength. The study involved 620 women 25-73 yr of age. The five muscle groups assessed were: grip, plantarflexors, hip abductors, trunk flexors, and trunk extensors. Pearson correlations yielded significant negative correlations of muscle stren...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract:PURPOSE:Stroke volume response to exercise depends on changes in cardiac filling, intrinsic myocardial contractility, and left ventricular afterload. The purpose of this study was to compare these responses during an upright cycle test performed until exhaustion in children and adults. METHODS:Stroke volume, cardiac o...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200203000-00012
更新日期:2002-03-01 00:00:00
abstract:PURPOSE:Reducing ice friction was one of the motives for developing the klapskate. However, the magnitude of power dissipation that occurs with conventional skates when a skater plantar flexes his ankle and the tip of the blade is pressed into the ice has not been quantified previously. In this study, we examine how ic...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200103000-00025
更新日期:2001-03-01 00:00:00
abstract:PURPOSE:Hyperventilation increases the clearance of carbon monoxide (CO) from blood; thus, we hypothesized that CO elimination would be enhanced with exercise. Accordingly, this study examined the effect of exercise on the half-life of carboxyhemolobin elimination. METHODS:Six healthy subjects (three males and three f...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0b013e3182602a00
更新日期:2012-11-01 00:00:00
abstract::This study investigates the utility of two equations for predicting minimum wrestling weight and three equations for predicting body density for the population of high school wrestlers. A sample of 54 wrestlers was assessed for body density by underwater weighing, residual volume by helium dilution, and selected anthr...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1986-04-01 00:00:00
abstract:PURPOSE:The purpose of the present study was to examine the effect of muscle activity level on serum creatine kinase (CK) activity after high-force eccentric exercise of the elbow flexors. METHODS:Twenty-six male volunteers were randomly assigned to one of three groups for a 4-d treatment period after exercise: immobi...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1097/00005768-200009000-00011
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVES:To examine if the associations between motor competence and physical activity and musculoskeletal fitness change over time, whether motor competence is associated with longitudinal trajectories of physical activity and fitness, and mediating pathways among these constructs across early childhood. METHODS:Fo...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002388
更新日期:2020-11-01 00:00:00