Abstract:
:Estradiol-17 beta labeled with deuterium in the positions 2 or 4 can be prepared from 2-chloromercurio-1,3,5(10)-estratriene-3,17 beta-diol 3-methyl ether 17-acetate or 4-chloromercurio-1,3,5(10)-estratriene-3,17 beta-diol, respectively, in refluxing CH3COO(2)H/(2)H2O. The same reaction performed on 4-acetoxymercurio-1,3,5(10)-estratriene-3,17 beta-diol afforded 2,4-dideuterio-estradiol-17 beta in good yields.
journal_name
Steroidsjournal_title
Steroidsauthors
Ferraboschi P,Ravasi M,Santaniello Edoi
10.1016/0039-128x(83)90052-1subject
Has Abstractpub_date
1983-06-01 00:00:00pages
777-82issue
6eissn
0039-128Xissn
1878-5867pii
0039-128X(83)90052-1journal_volume
41pub_type
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