The color and size of chili peppers (Capsicum annuum) influence Hep-G2 cell growth.

Abstract:

:Four types of chili (Capsicum annuum) extracts, categorized according to color; green and red, and size; small and large were studied in Hep-G2 cells. Red small (RS) chili had an LC50 value of 0.378 ± 0.029 compared to green big (GB) 1.034 ± 0.061 and green small (GS) 1.070 ± 0.21 mg/mL. Red big (RB) was not cytotoxic. Capsaicin content was highest in RS and produced a greater percentage sub-G1 cells (6.47 ± 1.8%) after 24 h compared to GS (2.96 ± 1.3%) and control (1.29 ± 0.8%) cells. G2/M phase was reduced by GS compared to RS and control cells. RS at the LC50 concentration contained 1.6 times the amount of pure capsaicin LC50 to achieve the same effect of capsaicin alone. GS and GB capsaicin content at the LC50 value was lower (0.2 and 0.66, respectively) compared to the amount of capsaicin to achieve a similar reduction in cell growth.

journal_name

Int J Food Sci Nutr

authors

Popovich DG,Sia SY,Zhang W,Lim ML

doi

10.3109/09637486.2014.931358

subject

Has Abstract

pub_date

2014-11-01 00:00:00

pages

881-5

issue

7

eissn

0963-7486

issn

1465-3478

journal_volume

65

pub_type

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