Abstract:
:Four toluene abusers had evidence of severe multifocal central nervous system damage. Impairment of cognitive, cerebellar, brainstem, auditory, and pyramidal tract function, as well as CT evidence of cerebral cortical, cerebellar, and brainstem atrophy, have been noted. In addition, we found opsoclonus, ocular flutter, and ocular dysmetria. All three patients tested had abnormal brainstem auditory evoked potentials, indicative of brainstem dysfunction. The patient with opsoclonus had CT evidence of brainstem, cerebellar, and cerebral cortical atrophy.
journal_name
Neurologyjournal_title
Neurologyauthors
Lazar RB,Ho SU,Melen O,Daghestani ANdoi
10.1212/wnl.33.10.1337subject
Has Abstractpub_date
1983-10-01 00:00:00pages
1337-40issue
10eissn
0028-3878issn
1526-632Xjournal_volume
33pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract:OBJECTIVE:To investigate the sensitivity of MRI of the spine compared with CT myelography (CTM) in detecting CSF leaks. METHODS:Between July 1998 and October 2010, 12 patients with orthostatic headache and a CTM-confirmed spinal CSF leak underwent an MRI of the spine with and without contrast. Using CTM as the gold st...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000435555.13695.22
更新日期:2013-11-12 00:00:00
abstract:OBJECTIVE:To devise a neurophysiologic strategy to select X-linked Charcot-Marie-Tooth neuropathy syndrome (CMTX) families for connexin 32 mutation screening. BACKGROUND:Once the common chromosome 17 DNA duplication (CMT1A syndrome) has been excluded, clinical features are not sufficiently distinctive to select which ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.51.5.1412
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:Autonomic symptoms may occur frequently in diabetic and other neuropathies. There is a need to develop a simple instrument to measure autonomic symptoms in subjects with neuropathy and to test the validity of the instrument. METHODS:The Survey of Autonomic Symptoms (SAS) consists of 11 items in women and 12 ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3182120147
更新日期:2011-03-22 00:00:00
abstract:OBJECTIVE:To investigate the etiology of aseptic meningitis and encephalitis in an adult population using modern microbiologic methods. METHODS:Consecutive patients (ages > or =16) with aseptic meningitis or encephalitis treated in Turku University Hospital, Finland, during 1999 to 2003 were included in the study. Mic...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000191407.81333.00
更新日期:2006-01-10 00:00:00
abstract::"Healthy citizens are the greatest asset any country can have."-Sir Winston Churchill. ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000000053
更新日期:2014-01-28 00:00:00
abstract::Hirayama disease is a nonprogressive, asymmetric amyotrophy of the hands and forearms, possibly caused by compression of the lower cervical cord on neck flexion. The authors used phase-contrast MR angiography to study a patient with this disorder and observed abnormal spinal epidural venous dilation on neck flexion. I...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000120665.81001.40
更新日期:2004-04-27 00:00:00
abstract::There was a report of spongiform encephalopathy transmitted to Syrian hamsters by intracerebral inoculation with the blood buffy coat of patients with Alzheimer's disease (AD) and their unaffected first-degree relatives. We attempted to verify that report, taking measures to reduce the risk of contaminating samples wi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.44.6.1111
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVE:To determine whether whole-brain, event-related fMRI can distinguish healthy older adults with known Alzheimer disease (AD) risk factors (family history, APOE epsilon4) from controls using a semantic memory task involving discrimination of famous from unfamiliar names. METHODS:Sixty-nine cognitively asymptom...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181b389ad
更新日期:2009-08-25 00:00:00
abstract::We studied five patients with nonhemorrhagic thalamic infarction with neuropsychological tests, CT, and somatosensory evoked responses (SERs). The three patients with left thalamic lesions had abnormalities of language, memory, visuospatial processing, intellect, and personality-changes compatible with dementia. The t...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.34.1.14
更新日期:1984-01-01 00:00:00
abstract:OBJECTIVE:To describe a large series of BIN1 patients, in which a novel founder mutation in the Roma population of southern Spain has been identified. METHODS:Patients diagnosed with centronuclear myopathy (CNM) at 5 major reference centers for neuromuscular disease in Spain (n = 53) were screened for BIN1 mutations. ...
journal_title:Neurology
pub_type: 杂志文章,多中心研究
doi:10.1212/WNL.0000000000005862
更新日期:2018-07-24 00:00:00
abstract:OBJECTIVE:To determine serial MRI and CT abnormalities around calcified cysts due to cysticercosis in previously treated patients during periods of seizure activity. BACKGROUND:Some patients with calcified lesions due to cysticercosis have seizures. How and why seizures occur in this setting are unknown. METHODS:Thre...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.53.4.777
更新日期:1999-09-11 00:00:00
abstract::INeuro@neurolist.mcg. edu: An e-mail discussion list for neurologists Neuro@neurolist.mcg.edu (Neurolist) is a discussion list for neurologists. This Internet tool, established in 1994, allows the worldwide community of neurologists to communicate quickly and efficiently using e-mail, web browsers, and newsreaders. Ne...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.52.9.1891
更新日期:1999-06-10 00:00:00
abstract::We tested the hypothesis that an anticardiolipin antibody (aCL) titer of > or = 10 IgG phospholipid (GPL) at the time of an index ischemic stroke is associated with an increased risk of subsequent thrombo-occlusive events or death. First-time ischemic stroke patients from the Antiphospholipid Antibodies and Stroke Stu...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.48.1.91
更新日期:1997-01-01 00:00:00
abstract::Patients with "reflex sympathetic dystrophy" or "causalgia" underwent sympathetic blocks. In protocol A (77 patients), we infused placebo (saline) for 30 minutes followed by phentolamine (35 mg). In protocol B (23 patients), the saline phase was followed by double-blind infusion of phentolamine or phenylephrine (500 m...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.44.6.1003
更新日期:1994-06-01 00:00:00
abstract::In a 20-year-old patient with the classic form of Pelizaeus-Merzbacher disease, electroencephalograms during wakefulness were moderately diffusely abnormal, and an overnight polygraphic sleep recording showed distorted nonrapid eye movement sleep patterns without vertex sharp waves, K-complexes, spindles, or positive ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.26.11.1042
更新日期:1976-11-01 00:00:00
abstract:BACKGROUND:Silent infarcts are commonly discovered on cranial MRI in the elderly. OBJECTIVE:To examine the association between risk of stroke and presence of silent infarcts, alone and in combination with other stroke risk factors. METHODS:Participants (3,324) in the Cardiovascular Health Study (CHS) without a histor...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.7.1222
更新日期:2001-10-09 00:00:00
abstract::We observed a highly topographically specific and consistent pattern of degeneration in the auditory system of Alzheimer's disease (AD) patients. Senile plaques (SP) and neurofibrillary tangles (NFT) were distributed throughout the ventral nucleus of the medial geniculate body (MGB) and the central nucleus of the infe...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.43.4.779
更新日期:1993-04-01 00:00:00
abstract:OBJECTIVE:Rebleeding of an aneurysm is a leading cause of morbidity and mortality after subarachnoid hemorrhage (SAH). Whereas numerous studies have demonstrated the risk factors associated with rebleeding, few data on complications of rebleeding, including its effect on the development of delayed cerebral ischemia (DC...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31823ed0a4
更新日期:2012-01-03 00:00:00
abstract::While intracranial tuberculomas have become uncommon in industrial nations, 12 patients with signs and symptoms of an intracranial mass lesion were recently found to have tuberculomas. Clinical findings suggestive of tuberculosis were frequently subtle or absent. Five patients did not have extracranial tuberculosis. T...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.28.3.256
更新日期:1978-03-01 00:00:00
abstract::In 64 patients with Parkinson's disease (PD), the basal level of prolactin (PRL) was normal. Bromocriptine (BCT) caused a significant suppression of PRL in all parkinsonian patients and controls. When given after BCT treatment, thyrotropin-releasing hormone (TRH) induced a significantly lower PRL rise in recent-onset ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.36.3.393
更新日期:1986-03-01 00:00:00
abstract::Recent positive trials have thrust acute cerebral perfusion imaging into the routine evaluation of acute ischemic stroke. Updated guidelines state that in patients with anterior circulation large vessel occlusions presenting beyond 6 hours from time last known well, advanced imaging selection including perfusion-based...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/WNL.0000000000008481
更新日期:2019-11-12 00:00:00
abstract::The clinical and genetic features of three non-Portuguese and non-Japanese patients with aprataxin gene mutations are reported. Patient 1 came from Italy and presented with typical ataxia with ocular motor apraxia (OMA). She was homozygous for the W279X nonsense mutation, which is associated with the Portuguese foundi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000048562.88536.a4
更新日期:2003-03-11 00:00:00
abstract:BACKGROUND/OBJECTIVE:Neglect has been attributed to sensory-attentional, motor-intentional, and representational disorders. Although patients with neglect may have defective visual exploration, the nature of this exploration deficit has not been entirely elucidated. The purpose of this study is to learn how, compared w...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.49.4.936
更新日期:1997-10-01 00:00:00
abstract::The authors performed serial transcranial Doppler (TCD) and carbon dioxide reactivity (CO2R) testing in 20 aneurysmal subarachnoid hemorrhage patients to determine whether impaired cerebrovascular reactivity was associated with symptomatic vasospasm. Symptomatic vasospasm occurred in 9 of 14 patients with abnormal CO2...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000200777.96896.3d
更新日期:2006-03-14 00:00:00
abstract::We evaluated 14 patients with idiopathic optic neuritis, 50 years of age or older, within 1 month of symptomatic onset from 1980 through 1985. We obtained follow-up information from case records an average of 13 months after initial examination and from telephone interviews an average of 57 months after initial evalua...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.12.1834
更新日期:1988-12-01 00:00:00
abstract:BACKGROUND:Few population-based studies with long-term follow-up have compared risk of recurrent stroke and cardiac events after first ischemic stroke. The relative risk of these two outcomes may inform treatment decisions. METHODS:In the population-based Northern Manhattan Study, first ischemic stroke patients age 40...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000201253.93811.f6
更新日期:2006-03-14 00:00:00
abstract::Three patients with postanoxic intention myoclonus, two patients with intention tremor, and one patient with cerebral palsy were administered L-5-hydroxytryptophan (L-5HTP), the precursor of serotonin, in combination with MK 486, a peripheral amino acid decarboxylase inhibitor. L-5HTP combined with MK 486 were potent ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.25.2.135
更新日期:1975-02-01 00:00:00
abstract::We compared the neurologic and cognitive performance of 15 young veterans who suffered unilateral penetrating missile wounds to the basal forebrain 15 years ago in the Vietnam War with uninjured controls and patients with lesions elsewhere in the brain. The subjects performed worse on tests of episodic memory, reasoni...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.36.4.459
更新日期:1986-04-01 00:00:00
abstract::The urinary excretion of some important phenylethylamines, catecholamines, their metabolites, amphetamine, and methamphetamine were measured in parkinsonian patients on Sinemet (L-dopa plus carbidopa, a peripheral dopadecarboxylase inhibitor) and depressed patients after chronic (-) deprenyl treatment. Deprenyl was ef...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.32.5.503
更新日期:1982-05-01 00:00:00
abstract::We investigated tyrosine-hydroxylase (TH)-immunoreactive neurons in the medulla oblongata corresponding to the A1 and A2 cell groups in autopsy tissue of patients with Parkinson's disease (PD) (n = 3), progressive supranuclear palsy (PSP) (n = 3), striatonigral degeneration (SND) (n = 2), and in controls (n = 4). The ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.40.11.1739
更新日期:1990-11-01 00:00:00