Abstract:
:In an effort to decrease the large number of patients who develop hypothyroidism after operations for Graves' disease, an identical modification of the conventional subtotal thyroidectomy (CST) was independently designed and tested in a prospective study at two institutions. The modified subtotal thyroidectomy (MST) essentially consists of leaving an accurately measured 5 gm thyroid remnant and an intact inferior thyroid artery on each side of the neck. By use of MST, euthyroidism, as demonstrated by serial clinical and thyroid function tests, has been achieved in 92% of a combined group of 107 patients followed longer than 2 years (average 62.1 months). Postoperative hypothyroidism developed in only two cases (2%), representing a marked improvement over the 40% to 75% rate of hypothyroidism resulting from CST. Recurrent hyperthyroidism occurred in only six cases, a rate of recurrence indistinguishable from that resulting from the more extensive resection required by CST. Enlargment of total remnant size to a total of 10 gm significantly improves long-term postoperative functional results without risking an increase in recurrence. The functional results obtained after MST are superior to those obtained after treatment with radioiodine and justify renewed interest in the surgical treatment of Graves' disease.
journal_name
Surgeryjournal_title
Surgeryauthors
Bradley EI 3rd,Liechty RDsubject
Has Abstractpub_date
1983-12-01 00:00:00pages
955-8issue
6eissn
0039-6060issn
1532-7361pii
0039-6060(83)90407-5journal_volume
94pub_type
杂志文章相关文献
SURGERY文献大全abstract:BACKGROUND:The nonparenchymal cells (NPC) of the liver have strong cytotoxic activity. Our hypothesis is that their activity may be imparted by obstructive jaundice and show recovery after biliary drainage. METHODS:In Donryu rats, we performed either a sham operation (group C; n = 5), production of irreversible obstru...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
abstract:BACKGROUND:The reversibility of the morphologic and functional alterations that occur in veins transplanted into the arterial circulation was examined in this study. METHODS:Common carotid vein bypass grafts (VG) were performed in 20 male New Zealand White rabbits. Ten VG and jugular veins (CV) were harvested after 14...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1993-08-01 00:00:00
abstract::The main goal of surgery for retroperitoneal fibrosis is to free the ureters from sclerotic tissue and pressure them from further extension of the disease; the omentum may be used as an efficient barrier against recurrence of fibrosis. We present 11 patients with idiopathic retroperitoneal fibrosis treated with ureter...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1982-02-01 00:00:00
abstract::The acquired failure of host immunocompetence that may result from significant protein and caloric malnutrition has been associated with an increased incidence of septic complications in patients undergoing operation. Wound infection in patients undergoing vascular surgical procedures may lead to exposure or contamina...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1983-06-01 00:00:00
abstract:BACKGROUND:Women in low- and middle-income countries account for 51% of breast cancer cases globally. These patients often delay seeking care and, therefore, present with advanced disease, partly because of fear of catastrophic health care expenses. Although there have been efforts to make health care affordable in low...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2015.04.040
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:The effect of the time interval between colorectal and liver resection for metastatic lesions on the patient's survival remains controversial. Pretreatment classification for predicting the prognosis of this disease has not yet been reported. METHODS:Nine clinical factors revealed by preoperative examinatio...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2001.112001
更新日期:2001-04-01 00:00:00
abstract::We investigated the active enhancement of liver allografts in 44 pairs of beagle dogs by pretreatment with semisoluble and soluble donor-specific spleen antigens. If the antigen were administered together with prednisolone, time of survival was significantly prolonged--with soluble antigen by 36.8 +/- 5.9 days and wit...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1976-11-01 00:00:00
abstract::Forty-five consecutive patients with 49 fractures of the first rib caused by blunt trauma underwent arteriography. The fractures were classified as posterior, lateral, or anterior and as nondisplaced, minimally displaced, or significantly displaced. Seven patients (14%) had serious vascular injuries: five had posterio...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Pancreatic polypeptide (PP) deficiency has been associated with impaired hepatic sensitivity to insulin and pancreatogenic diabetes in chronic pancreatitis. Since pancreatic resection might also result in PP deficiency, hepatic responses to insulin infusion (0.25 mU/kg/min) were determined by the euglycemic glucose cl...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
abstract::The quantitative effects of cytomegalovirus (CMV) infection on morbidity and mortality rates were examined in 320 renal transplant cases. With the use of virus cultures and CMV antibody measurements, all patients were studied, regardless of symptoms, from a time before transplantation to at least 1 year, 11 months aft...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1981-06-01 00:00:00
abstract:BACKGROUND:Our purpose was to determine whether the combination of total liver vascular inflow occlusion (Pringle maneuver) and rapid hepatic transection with a clamp-crush technique results in significant reduction of blood loss and transfusion requirements during major hepatic resections. METHODS:A series of 49 adul...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:Ischemia-reperfusion injury of skeletal muscle is a common clinical and experimental problem. To date, there has been no uniform and reproducible method to assess the extent of histologic injury. In this study, we developed a novel statistical methodology for evaluating injury in individual myocytes and 3 di...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2007.06.005
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Lung injury is a life-threatening complication in patients with liver dysfunction. We recently provided an experimental lung injury model in mouse with common bile duct ligation. In this study, we aimed to characterize the pathologic and biochemical features of lung tissues in common bile duct ligation mice ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2016.12.017
更新日期:2017-06-01 00:00:00
abstract::To assess the role of portal hemodynamics in the development of postshunt encephalopathy, we studied 19 patients after small-diameter portacaval H grafting (SD-PCHG). We used contrast studies as well as technetium-labeled macroaggregated albumin injected into the portal vein to assess direction of portal flow. We then...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1984-08-01 00:00:00
abstract:BACKGROUND:Previously we demonstrated that optimal doses of tumor-infiltrating lymphocytes (TIL) concomitant with recombinant interleukin-2 (rIL-2) effectively mediated complete tumor regression of murine 3-day pulmonary metastases. METHODS:In the present study we have investigated the contribution of the host immune ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/s0039-6060(05)80209-0
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:Sclerotherapy is usually effective in controlling acutely bleeding esophageal varices. It may not be as effective as shunt surgery for prevention of rebleeding; therefore we undertook a prospective study comparing interposition mesocaval shunt (MCS) and repeated sclerotherapy. METHODS:Forty-five patients (m...
journal_title:Surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0039-6060(05)80248-x
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:Gastric cancer is an aggressive disease, and overall changes in incidence rates have been noted. There are conflicting data on whether young patients have worse outcomes than older patients; the roles of tumor biology and access to care are critical to answering this question. Our objectives were to explore ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2013.05.017
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:The relationship between myopenia, nutritional status, and long-term oncologic outcomes remains poorly characterized in patients with clinically resectable pancreatic cancer. We sought to reliably quantify prognostic indicators of preoperative cachexia in a manner applicable to any clinical setting. METHODS...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2016.09.038
更新日期:2017-04-01 00:00:00
abstract::Radiation for benign problems of the head and neck area has been uniformly recognized as unacceptable practice. This includes epilation for facial hirsutism. Twelve such patients, recently encountered, have characteristic radiodermatitis facies and have demonstrated multisite neoplastic involvement--including skin, th...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::Hypertriglyceridemia commonly accompanies clinical sepsis and may be caused by increased hepatic production or decreased clearance of triglyceride from the bloodstream. In contrast, enhanced lipid clearing capacity is usually seen after uncomplicated trauma. The purpose of the study was to determine the role of lipopr...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1981-08-01 00:00:00
abstract:BACKGROUND:The presence or absence of lymph node metastases is known to be an important prognostic factor for patients with pancreatic cancer. Few studies have investigated the ratio of the number of lymph nodes harboring metastatic cancer to the total number of lymph nodes examined (lymph node ratio [LNR]) with regard...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2006.12.013
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:Our ability to predict respiratory compromise during general anesthesia in a child with an anterior mediastinal mass is limited. Two prior reports have found a correlation between adequacy of ventilation during general anesthesia and the tracheal cross-sectional area obtained from computed tomograms (compute...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/s0039-6060(05)80360-5
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND:An overproduction of corticosterone during severe sepsis results in increased apoptosis of immune cells, which may result in relative immunosuppression and an impaired ability to fight infections. We have previously demonstrated that administration of tubastatin A, a selective inhibitor of histone deacetylas...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2014.03.033
更新日期:2014-08-01 00:00:00
abstract::A conical silicone rubber balloon was placed in the left hemithorax of fetal lambs and progressively inflated through an exteriorized catheter over the last trimester. Newborn lambs died of severe respiratory insufficiency, despite maximal resuscitation. The lungs were markedly hypoplastic with greatly reduced parench...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1980-07-01 00:00:00
abstract:BACKGROUND:Health care costs continue to spiral; aggregate costs for 1992 are $850 billion, 13.6% of the U.S. gross national product. The issue has assumed national proportions, and change appears to be on the federal agenda. Great interest in surgical expenditures exists, which comprise 30.1% of all health care outlay...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
abstract::A patient who underwent jejunoileal bypass for morbid obesity developed servere renal failure associated with hyperoxaluria and renal oxalosis. Renal function improved and oxalate excretion decreased following hemodialysis and restoration of gastrointestinal continuity. ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1977-11-01 00:00:00
abstract::The incidence of fascial disruption after major abdominal operations is 1% to 3%, and dehiscence is associated with a mortality rate of 15% to 20%. Although several systemic factors (e.g., malnutrition, increased age, male sex, and chronic treatment with steroids) have been associated with an increased risk of wound d...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1985-06-01 00:00:00
abstract:BACKGROUND:Adequate surgical care is lacking in many low- and middle-income countries because of diverse barriers preventing patients from reaching providers. We sought to assess perceived difficulties to accessing surgical care in Nepal using the Surgeons OverSeas Assessment of Surgical Need tool. METHODS:Fifteen of ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2016.03.012
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:This study was performed to assess the relationship between Hashimoto's thyroiditis and the development, presentation, management, and outcome of papillary thyroid carcinoma. METHODS:Two complementary analytic methods were used. The clinical study was a retrospective case-control study, including patients s...
journal_title:Surgery
pub_type: 杂志文章,meta分析
doi:10.1067/msy.2099.101431
更新日期:1999-12-01 00:00:00
abstract::This study examined whether treatment with the oxygen free radical scavengers, superoxide dismutase and catalase, could improve functional recovery in hearts subjected to regional ischemia and global cardioplegic arrest. Regional left ventricular (LV) function was assessed in open chest pigs with sonomicrometry and mi...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1987-08-01 00:00:00