Abstract:
:A method is presented for encapsulating high molecular weight biological materials such as viral antigen, concanavalin A, and other proteins with cellulose acetate phthalate. The method is simple, inexpensive, and rapid; the process takes approximately 15 min. Capsules generated by this method are produced as microspheres 1-3 mm in diameter. They are stable for at least 6 h in simulated gastric conditions, but disintegrate rapidly under simulated intestinal conditions. Encapsulation had no effect on the activity of the biological materials. The method has potentially wide application for encapsulation of drugs and other substances.
journal_name
J Pharm Scijournal_title
Journal of pharmaceutical sciencesauthors
Maharaj I,Nairn JG,Campbell JBdoi
10.1002/jps.2600730110subject
Has Abstractpub_date
1984-01-01 00:00:00pages
39-42issue
1eissn
0022-3549issn
1520-6017pii
S0022-3549(15)44955-Xjournal_volume
73pub_type
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