Cytophotometric and cytogenetic characteristics of primary hepatomas induced in Wistar rats by aflatoxin B1.

Abstract:

:Karyograms of the primary hepatomas induced in Wistar rats by aflatoxin b1 exhibited hypodiploid chromosome sets, and destruction of the chromosomes. Cytophotometric investigations showed a decrease of DNA content in the neoplastic cells, even to about 40% of DNA content in the normal hepatocytes in rats. In the neoplastic destruction of the chromatin material in these hepatomas breaks and deletion of the chromatids predominate.

journal_name

Neoplasma

journal_title

Neoplasma

authors

Gasiorowski K,Zawirska B

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

151-7

issue

2

eissn

0028-2685

issn

1338-4317

journal_volume

28

pub_type

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