Abstract：
:The uric-acid lowering effect was investigated in a group of 2220 patients. 1984 of these were employed for statistical evaluation purposes. On average, the uric acid level was reduced from 8,24 +/- 1,16 mg/100 ml to 5,32 +/- 1,265 mg/100 ml. In 82 % of all the cases, the uric acid level at the end of the treatment period was below 6,4 mg%, both in patients treated throughout with 50 mg benzbromarone (NarcaricinRmite) and in those changed over to 100 mg benzbromarone (NarcaricinR) after 1 to 3 weeks. The lowering of the uric acid levels was in no way related to hypertension, adiposity, hyperlipoproteinaemia, diabetes mellitus or age.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Ferber H,Bader U,Matzkies Fdoi
10.1007/978-1-4615-9140-5_47subject
Has Abstractpub_date
1980-01-01 00:00:00pages
287-94eissn
0065-2598issn
2214-8019journal_volume
122Apub_type
临床试验,杂志文章abstract：:Heart disease is widely believed to develop from two pathological processes. Circulating lipoproteins containing the nondegradable lipid, cholesterol, accumulate within the arterial wall and perhaps are oxidized to more toxic lipids. Both lipid accumulation and vascular reaction to the lipids lead to the gradual thick...
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