Abstract:
:A technique for simplified heterotopic rat heart transplantation having only aorto-aortic anastomosis is presented. The heterotopic rt heart survives and functions well when one lung lobe is attached t the transplantation and functions as a reservoir. Iso- and allotransplants are compared by electrocardiogram (ECG) determination and histological examination. Isotransplants exhibited normal heart and lung throughout the 6-month observation period. allotransplants ceased to function by the 16th postoperative day, with the cessation of palpable heart beat over the abdominal wall by the 10th postoperative day. This simplified heterotopic rat heart transplantation model can be operated by nonsurgeons in an unhurried manner with minimal training in microvascular surgery, and can be applied to various transplantation immunological studies.
journal_name
Transplantationjournal_title
Transplantationauthors
Lee S,Macedo AR,Curtis GP,Lee D,Orloff MJdoi
10.1097/00007890-198204000-00020subject
Has Abstractpub_date
1982-04-01 00:00:00pages
438-42issue
4eissn
0041-1337issn
1534-6080journal_volume
33pub_type
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