New insights into the pathophysiology, classification, and diagnosis of coronary microvascular dysfunction.

abstract：OBJECTIVE:Noninvasive flow-mediated vasodilation (FMD) is a widely used method to assess endothelial function, but its technical difficulty and problems remain obstacles for use in clinical practice. Reactive hyperemia-peripheral arterial tonometry (RH-PAT) was developed as a simpler and more reproducible method. We co...

journal_title：Coronary artery disease

authors： Woo JS,Jang WS,Kim HS,Lee JH,Choi EY,Kim JB,Kim WS,Kim KS,Kim W

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Coronary artery ectasia has been defined as localized or diffuse nonobstructive lesions of the epicardial coronary arteries with a luminal dilation exceeding the 1.5-fold of normal adjacent segment or vessel diameter. Although coronary artery disease is supposed to be responsible for more than 50% of coronar...

journal_title：Coronary artery disease

authors： Aksoy Y,Acikgoz N,Sivri N,Bariskaner E,Akturk E,Turhan H,Yetkin E

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Circulating leukocytes are recruited at atherosclerotic sites through a family of adhesion molecules. Circulating forms of adhesion molecules in peripheral blood can be quantified now. OBJECTIVE:To evaluate the relationship between circulating adhesion molecules and severity of coronary atherosclerosis. ME...

journal_title：Coronary artery disease

authors： Oishi Y,Wakatsuki T,Nishikado A,Oki T,Ito S

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Pregnancy-associated plasma protein-A (PAPP-A) is a high-molecular-weight, zinc-binding matrix metalloproteinase that is known to be abundantly expressed in ruptured plaques. Previous studies have shown PAPP-A to be a significant marker of plaque instability and cardiovascular events in patients with acute c...

journal_title：Coronary artery disease

authors： Park S,Youn JC,Shin DJ,Park CM,Kim JS,Ko YG,Choi D,Ha JW,Jang Y,Chung N

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:In-stent restenosis (ISR) and lesion progression are major obstacles for a percutaneous coronary intervention (PCI). Although previous studies have suggested that inflammation and lipid profile may be involved in those pathophysiological events, it remains controversial to date. The aim of the present study w...

journal_title：Coronary artery disease

authors： Xu HY,Qiao SB,Zhang JF,Dong QT,Li JJ

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:Considerable evidence suggests that thyroid dysfunction, especially hypothyroidism, may lead to coronary artery disease (CAD). The aim of this study is to investigate the effect of low serum levels of free triiodothyronine (FT3) on coronary artery calcification in outpatients with suspected CAD and the occurr...

journal_title：Coronary artery disease

authors： Zhu L,Gao C,Wang X,Qi D,Zhang Y,Li M,Liu W,Hao P

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Although atherosclerosis is supposed to be responsible for more than 50% of coronary artery ectasia, the precise pathology of coronary artery ectasia is not clearly understood. A histopathological examination of ectatic segments has revealed mainly destruction of the media layer of the artery. In the present...

journal_title：Coronary artery disease

authors： Yetkin E,Acikgoz N,Aksoy Y,Bariskaner E,Sivri N,Akturk E,Turhan H,Kosar F,Cehreli S

更新日期：2005-12-01 00:00:00

abstract：AIM:To determine how hypertension affects the left ventricular diastolic function of patients with effort angina. METHODS:We performed radionuclide ventriculography in 14 patients with isolated stenosis of the left anterior descending coronary artery and in seven healthy volunteers. RESULTS:Neither global nor regiona...

journal_title：Coronary artery disease

authors： Nii T,Arakawa K

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:We hypothesized that an increase in plasminogen activator inhibitor 1 (PAI-1) might reduce low-density lipoprotein (LDL) particle size in conjunction with triglyceride (TG) metabolism disorder, resulting in an increased risk of atherosclerotic cardiovascular disease (ASCVD). METHODS:This study was carried o...

journal_title：Coronary artery disease

authors： Iida K,Tani S,Atsumi W,Yagi T,Kawauchi K,Matsumoto N,Hirayama A

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV), Chlamydia pneumoniae (C. pneumoniae), and Helicobacter pylori (H. pylori) have been implicated in atherosclerosis and restenosis after angioplasty. The patterns of distribution within coronary lesions and possible coinfections of these pathogens in the coronary vasculature had not prev...

journal_title：Coronary artery disease

authors： Radke PW,Merkelbach-Bruse S,Messmer BJ,vom Dahl J,Dörge H,Naami A,Vogel G,Handt S,Hanrath P

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Although coronary artery bypass graft surgery (CABG) has been proven to have mortality and morbidity benefits in patients with non-ST elevation myocardial infarction and multivessel disease, the appropriate timing of this procedure remains unclear. Therefore, we proposed a propensity score-matched analysis c...

journal_title：Coronary artery disease

authors： Ha LD,Ogunbayo G,Elbadawi A,Olorunfemi O,Messerli A

更新日期：2017-12-01 00:00:00

abstract：:Cardiac hypertrophy is a physiological adaptive response by the heart to pressure overload. However, after prolonged periods, this initial adaptive response becomes maladaptive, leading to increased mortality and morbidity from heart failure. Recently, 3-hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibit...

journal_title：Coronary artery disease

authors： Nakagami H,Liao JK

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the association of widowhood with the severity and extent of coronary artery disease (CAD), and whether it is modified by sex or socioeconomic status. PATIENTS AND METHODS:A total of 1068 patients undergoing coronary angiography at five centers in Saudi Arabia and the Uni...

journal_title：Coronary artery disease

authors： Daoulah A,Alama MN,Elkhateeb OE,Al-Murayeh M,Al-Kaabi S,Al-Faifi SM,Alosaimi HM,Lotfi A,Asiri KS,Elimam AM,Abougalambo AS,Murad W,Haddara MM,Dixon CM,Alsheikh-Ali AA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The effects of initial tests on long-term events have been unknown. PATIENTS AND METHODS:In this observational retrospective study, we analyzed the effects of initial noninvasive tests by myocardial perfusion imaging (MPI) and computed tomography angiography (CTA) on long-term major adverse cardiac events (...

journal_title：Coronary artery disease

authors： Naya M,Uemura Y,Matsumoto N,Momose M,Kato T,Hida S,Yamauchi T,Nakajima T,Suzuki E,Tamaki N,J-COMPASS Extended Follow-Up Study Group.

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Treatment of coronary in-stent restenosis (ISR) remains challenging in contemporary clinical applications. Drug-coated balloon (DCB) angioplasty offers an effective treatment for ISR. Shenqi is a novel iopromide-based paclitaxel-coated balloon and its clinical safety, effectiveness and angiographic efficacy ...

journal_title：Coronary artery disease

authors： Zhu J,Liu L,Zhu Z,Yang Z,Hu J,Ding F,Zhou Y,Su X,Ge J,Liu X,Tang L,He Y,Zhou G,Ji Z,Li Y,Pang W,Zhang R

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:ABO blood groups have been associated with venous thromboembolism and arterial thrombosis. Although platelets play key roles in thrombogenesis, the relation between ABO groups and platelets is not well known and was investigated in this study. PATIENTS AND METHODS:ABO blood type information was retrospectiv...

journal_title：Coronary artery disease

authors： Timur AA,Barnard J,Murugesan G,Gandhi S,Bhatt DL,Kottke-Marchant K

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:We report on 10 patients with Kawasaki disease and thrombocytopenia who were found to have a high incidence of coronary artery aneurysm and acute myocardial infarction. The clinical features of these patients, the cause of their thrombocytopenia and the relationship between cardiovascular pathology and throm...

journal_title：Coronary artery disease

authors： Niwa K,Aotsuka H,Hamada H,Uchishiba M,Terai M,Niimi H

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVES:YKL-40 is secreted by macrophages, including those in atherosclerotic plaques, neutrophils, and vascular smooth muscle cells. Circulating YKL-40 is elevated in patients with inflammation and increased tissue remodeling. The aim was to examine the sequential changes in serum YKL-40 in patients with acute myoc...

journal_title：Coronary artery disease

authors： Nøjgaard C,Høst NB,Christensen IJ,Poulsen SH,Egstrup K,Price PA,Johansen JS

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:For patients with severe ischemic heart disease, complete revascularization by a percutaneous coronary intervention or coronary artery bypass grafting is often not achieved and may still cause residual angina. In case of progressive coronary artery occlusions, therapeutic arteriogenesis constitutes a promisi...

journal_title：Coronary artery disease

authors： Krackhardt F,Harnoss JM,Waliszewski MW,Ritter Z,Granzow S,Felsenberg D,Neumann K,Lerman LO,Hillmeister P,Gebker R,Paetsch I,Riediger F,Bramlage P,Buschmann IR

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The degree of coronary collateral development is not same in every patient with similar degree of coronary stenosis. In animal studies monocyte chemoattractant protein-1 (MCP-1) has been found to be related to collateral vessel development. In this study we investigated whether a higher serum MCP-1 level is ...

journal_title：Coronary artery disease

authors： Sahinarslan A,Kocaman SA,Topal S,Ercin U,Bukan N,Yalcin R,Timurkaynak T

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:We sought to compare the long-term effectiveness and safety of triple antiplatelet therapy (TAPT) versus dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) for unprotected left main coronary artery disease (uLMCAD). BACKGROUND:An additional strategy to reduce recurrent ischemia ...

journal_title：Coronary artery disease

authors： Lee HJ,Yu CW,Hwang HK,Choi RK,Park JS,Li H,Ro YM

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate whether chronotropic incompetence (CI), the inability to reach 85% of the maximal predicted heart rate during exercise, affects the assessment of myocardial ischemia and prognosis in patients undergoing myocardial perfusion single-photon emission computed tomography (MPS)...

journal_title：Coronary artery disease

authors： De Lorenzo A,Oliveira G,Ramos AC,Pinto F,Rothstein T,Lima RS

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To prospectively compare iopamidol 370, which is a low-osmolar contrast medium and iodixanol 320, which is an iso-osmolar contrast medium, in terms of image quality and nonserious adverse effects that have the potential to influence the image quality in a 16-slice multi-detector row computed tomography corona...

journal_title：Coronary artery disease

authors： Ozbulbul NI,Yurdakul M,Tola M

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) is a sensitive indicator of hemodynamic stress and its increased level is associated with higher mortality in acute coronary syndrome (ACS) patients. Virtual histology-intravascular ultrasound (VH-IVUS) can provide quantitative information on plaque ...

journal_title：Coronary artery disease

authors： Hong YJ,Ahn Y,Sim DS,Yoon NS,Yoon HJ,Kim KH,Park HW,Kim JH,Jeong MH,Cho JG,Park JC,Kang JC

更新日期：2009-12-01 00:00:00

abstract：:The Editor and Associate Editors are pleased that our readership will have the opportunity to benefit from a series of contributions by Dr John Rutherford addressing current issues in pharmacology and therapeutics pertinent to coronary artery disease. We are pleased also that Dr Rutherford will provide authoritative p...

journal_title：Coronary artery disease

authors： Rutherford JD

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:To maintain the integrity of tissues, endothelial cells play critical roles. Fas ligand (FasL) is well known to deliver a death signal through its receptor, Fas. The Fas/FasL system may concomitantly induce expressions of interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP-1) besides triggering ...

journal_title：Coronary artery disease

authors： Yamaoka-Tojo M,Yamaguchi S,Nitobe J,Abe S,Inoue S,Nozaki N,Okuyama M,Sata M,Kubota I,Nakamura H,Tomoike H

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:To assess the incidence, clinical significance, and independent risk factors of stroke in patients with acute myocardial infarction (AMI) treated invasively. MATERIALS AND METHODS:We analyzed 2520 consecutive patients with AMI admitted between 2003 and 2007. Data on long-term follow-up were screened to iden...

journal_title：Coronary artery disease

authors： Podolecki TS,Lenarczyk RK,Kowalczyk JP,Mazurek MH,Swiątkowski AM,Chodór PK,Pruszkowska-Skrzep PI,Sędkowska AA,Poloński L,Kalarus ZF

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Nitroglycerin (NTG) is known to increase the blood supply to the myocardium, and would thus increase the delivery of a perfusional tracer such as sestamibi (MIBI) to the tissue. The latter, in turn, would take up and concentrate the tracer to a greater extent than in basal conditions only if energy-dependent...

journal_title：Coronary artery disease

authors： Greco C,Tanzilli G,Ciavolella M,Sinatra R,Banci M,Schillaci O,Macrina F,Scopinaro F,Marino B,Campa PP

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:Early evaluation of patients with chest pain is important not only for the detection of acute myocardial infarction (AMI) but also for identification of patients at high risk for future cardiac events. A multimarker strategy applying results of early measurements of different biochemical markers of cardiac ne...

journal_title：Coronary artery disease

authors： Eggers KM,Oldgren J,Nordenskjöld A,Lindahl B

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Apoptotic cell death is the major form of myocardial damage produced by coronary ischemic events. OBJECTIVE:To assess whether circulating levels of soluble Fas (sFas), an inhibitor of apoptosis, and sFas ligand, an inducer of apoptosis, in patients with coronary artery disease are greater than normal. METH...

journal_title：Coronary artery disease

authors： Ohtsuka T,Hamada M,Sasaki O,Suzuki M,Hara Y,Shigematsu Y,Ohtani T,Honda T,Hiwada K

更新日期：1999-06-01 00:00:00