Abstract：
:Partially purified fractions from sheep pineal gland extracts, which show a fluorescence like pteridines, were shown to suppress the enzyme hydroxy-indole-o-methyltransferase (HIOMT) isolated from avian pineals and retinas. The results described demonstrate that the mechanism of inhibition of HIOMT activity is independent of the species and organ. A blocking effect was found in experiments whether retinal or pineal HIOMT were used and the effect was found as well with bovine HIOMT. It is shown that low molecular weight molecules show inhibitory activity and accompany the high molecular weight enzyme HIOMT.
journal_name
Life Scijournal_title
Life sciencesauthors
Ebels I,Cremer-Bartels Gdoi
10.1016/0024-3205(82)90022-4subject
Has Abstractpub_date
1982-04-19 00:00:00pages
1369-77issue
16eissn
0024-3205issn
1879-0631pii
0024-3205(82)90022-4journal_volume
30pub_type
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