Recurrent pneumonia in children and its relationship to bronchial hyperreactivity.

Abstract:

:To determine what conditions are most likely to cause persistent or recurrent pneumonia (PRP) in children, the records of 81 children referred to James Whitcomb Riley Hospital for Children for evaluation of PRP were reviewed. Twenty patients had an apparent underlying cause that predisposed them to PRP. Of the 61 remaining patients (mean age 3.8 years) without any apparent cause for PRP, 49% had a history of allergy or family history of asthma, 31% patients had a history of wheezing and 18% were wheezing during their initial visit. No patient had an elevated sweat chloride determination or immunoglobulin deficiency. Of the 12 patients who were able to be recalled for pulmonary function testing, three had airflow obstruction that responded to an inhaled bronchodilator (isoproterenol). Of the nine patients with normal function, eight responded to methacholine with a decrease from base line in the one-second forced expiratory volume of greater than 20%. In all, 92% of those tested had bronchial hyperreactivity. These results indicate that asthma is a common cause of PRP in children and that PRP may occur as the initial symptom even in the absence of wheezing.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Eigen H,Laughlin JJ,Homrighausen J

subject

Has Abstract

pub_date

1982-11-01 00:00:00

pages

698-704

issue

5

eissn

0031-4005

issn

1098-4275

journal_volume

70

pub_type

杂志文章
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    更新日期:2016-03-01 00:00:00

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    authors: Arrowsmith JB,Kennedy DL,Kuritsky JN,Faich GA

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    authors: Zima BT,Bussing R,Tang L,Zhang L

    更新日期:2013-03-01 00:00:00

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    authors: Bhutani VK,Committee on Fetus and Newborn.,American Academy of Pediatrics.

    更新日期:2011-10-01 00:00:00

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    pub_type: 杂志文章

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    authors: Donoghue AJ,Nadkarni VM,Elliott M,Durbin D,American Heart Assocation National Registry of Cardiopulmonary Resuscitation Investigators.

    更新日期:2006-09-01 00:00:00

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    pub_type: 杂志文章,评审

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    更新日期:2003-09-01 00:00:00

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    pub_type: 杂志文章,随机对照试验

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    更新日期:2009-06-01 00:00:00

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  • Early-Life Predictors of Fetal Alcohol Spectrum Disorders.

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    pub_type: 杂志文章

    doi:

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    更新日期:1990-09-01 00:00:00

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    pub_type: 杂志文章

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    authors: Zuckerman B,Stevens GD,Inkelas M,Halfon N

    更新日期:2004-12-01 00:00:00

  • Maternal psychological reaction to newborn genetic screening for type 1 diabetes.

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    pub_type: 杂志文章,多中心研究

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    authors: Kerruish NJ,Campbell-Stokes PL,Gray A,Merriman TR,Robertson SP,Taylor BJ

    更新日期:2007-08-01 00:00:00

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    pub_type: 杂志文章

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  • Uninterrupted Infant Sleep, Development, and Maternal Mood.

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    doi:10.1542/peds.2006-2132

    authors: Petit D,Touchette E,Tremblay RE,Boivin M,Montplaisir J

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    pub_type: 杂志文章,随机对照试验

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  • Enterovirus 71 infection: report of an outbreak with two cases of paralysis and a review of the literature.

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    pub_type: 杂志文章

    doi:10.1542/peds.108.5.1231

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    更新日期:2001-11-01 00:00:00

  • Teaching community pediatrics to pediatric residents: strategic approaches and successful models for education in community health and child advocacy.

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    更新日期:2020-08-01 00:00:00