Chromosomal localization of the Moloney sarcoma virus mouse cellular (c-mos) sequence.

abstract：:Suppression of interferon signaling is of paramount importance to a virus. Interferon signaling significantly reduces or halts the ability of a virus to replicate; therefore, viruses have evolved sophisticated mechanisms that suppress activation of the interferon pathway or responsiveness of the infected cell to inter...

journal_title：Journal of virology

authors： Olanubi O,Frost JR,Radko S,Pelka P

更新日期：2017-03-29 00:00:00

abstract：:When human A431 cells, which carry high numbers of epidermal growth factor (EGF) receptors, are exposed to EGF, the total content of phosphotyrosine in cell protein is increased, the EGF receptor becomes phosphorylated at tyrosine, and new phosphotyrosine-containing 36,000- and 81,000-dalton proteins are detected. We ...

journal_title：Journal of virology

authors： Cooper JA,Scolnick EM,Ozanne B,Hunter T

更新日期：1983-12-01 00:00:00

abstract：:To assess the effect of the polyomavirus (Py) early proteins, the large T (LT), middle T (MT), and small T (ST) antigens, on gene expression from the Py late promoter, replication-defective plasmid constructs with the bacterial chloramphenicol acetyltransferase (cat) gene linked to this promoter were cotransfected int...

journal_title：Journal of virology

authors： Kern FG,Pellegrini S,Cowie A,Basilico C

更新日期：1986-10-01 00:00:00

abstract：:We molecularly cloned JC polyomavirus DNAs from urine samples of eight nonimmunosuppressed patients and two healthy individuals. The cloned viral DNAs all contained an archetypal regulatory sequence from which various regulatory sequences of JC polyomavirus isolates derived from patients with progressive multifocal le...

journal_title：Journal of virology

authors： Yogo Y,Kitamura T,Sugimoto C,Ueki T,Aso Y,Hara K,Taguchi F

更新日期：1990-06-01 00:00:00

abstract：:Sequences and structures within the terminal genomic regions of plus-strand RNA viruses are targets for the binding of host proteins that modulate functions such as translation, RNA replication, and encapsidation. Using murine norovirus 1 (MNV-1), we describe the presence of long-range RNA-RNA interactions that were s...

journal_title：Journal of virology

authors： López-Manríquez E,Vashist S,Ureña L,Goodfellow I,Chavez P,Mora-Heredia JE,Cancio-Lonches C,Garrido E,Gutiérrez-Escolano AL

更新日期：2013-11-01 00:00:00

abstract：UNLABELLED:The encephalitic response to viral infection requires local chemokine production and the ensuing recruitment of immune and inflammatory leukocytes. Accordingly, chemokine receptors present themselves as plausible therapeutic targets for drugs aimed at limiting encephalitic responses. However, it remains uncl...

journal_title：Journal of virology

authors： Michlmayr D,McKimmie CS,Pingen M,Haxton B,Mansfield K,Johnson N,Fooks AR,Graham GJ

更新日期：2014-09-01 00:00:00

abstract：:When mouse L cells are infected for 22 hr with vesicular stomatitis virus (VSV), a ribonucleic acid-containing enveloped virus, greater than 70% of the major histocompatibility antigen (H-2), is no longer detectable by the method of inhibition of immune cytolysis. Infected cells prelabeled with (14)C-glucosamine also ...

journal_title：Journal of virology

authors： Hecht TT,Summers DF

更新日期：1972-10-01 00:00:00

abstract：:Information was sought on the temporal distribution of transmissible mink encephalopathy virus in royal pastel mink inoculated subcutaneously with 10(3.0) 50% intracerebral lethal doses of the Idaho strain. As determined by intracerebral assay in mink, extremely little replication of the virus occurred during the prec...

journal_title：Journal of virology

authors： Hadlow WJ,Race RE,Kennedy RC

更新日期：1987-10-01 00:00:00

abstract：:The Cas-Br-E murine leukemia virus is a nondefective retrovirus that induces non-T-, non-B-cell lymphomas in susceptible NIH/Swiss mice. By using a DNA probe derived from Cas-Br-E provirus-flanking sequences, we identified a DNA region, originally called Sic-1, rearranged in 16 of 24 tumors analyzed (67%). All proviru...

journal_title：Journal of virology

authors： Bergeron D,Poliquin L,Kozak CA,Rassart E

更新日期：1991-01-01 00:00:00

abstract：:We report that adaptation to infect the guinea pig did not modify the capacity of foot-and-mouth disease virus (FMDV) to kill suckling mice and to cause an acute and transmissible disease in the pig, an important natural host for this pathogen. Adaptive amino acid replacements (I(248)-->T in 2C, Q(44)-->R in 3A, and L...

journal_title：Journal of virology

authors： Núñez JI,Molina N,Baranowski E,Domingo E,Clark S,Burman A,Berryman S,Jackson T,Sobrino F

更新日期：2007-08-01 00:00:00

abstract：:We used deep sequencing of poly(A) RNA to characterize the transcriptome of an economically important eel virus, anguillid herpesvirus 1 (AngHV1), at a stage during the lytic life cycle when infectious virus was being produced. In contrast to the transcription of mammalian herpesviruses, the overall level of antisense...

journal_title：Journal of virology

authors： van Beurden SJ,Gatherer D,Kerr K,Galbraith J,Herzyk P,Peeters BP,Rottier PJ,Engelsma MY,Davison AJ

更新日期：2012-09-01 00:00:00

abstract：:The antiviral activity of the double-stranded complex poly(rI) . poly(rC) in cell culture was restored or even surpassed if the constituent homopolymers were administered separately. Poly(rI) primed the cells for the antiviral activity of poly(rC) and poly(rC) primed for poly(rI), but neither poly(rI) nor poly(rC) pri...

journal_title：Journal of virology

authors： De Clercq E,De Somer P

更新日期：1972-05-01 00:00:00

abstract：:The Chinese hamster cell lines E36 and CHOK1 dramatically differ in susceptibility to amphotropic murine leukemia virus (A-MuLV) and gibbon ape leukemia virus (GALV); E36 cells are highly susceptible to both viruses, CHOK1 cells are not. We have previously shown that GALV can infect E36 cells by using both its own rec...

journal_title：Journal of virology

authors： Chaudry GJ,Farrell KB,Ting YT,Schmitz C,Lie SY,Petropoulos CJ,Eiden MV

更新日期：1999-04-01 00:00:00

abstract：:The in vitro transcription pattern of simian virus 40 (SV40) deoxyribonucleic acid (DNA) by a mammalian ribonucleic acid (RNA) polymerase, was studied by electron microscopy and velocity sedimentation techniques. It was found that (i) the majority of supercoiled SV40 DNA molecules displayed a single binding site for t...

journal_title：Journal of virology

authors： Herzberg M,Winocour E

更新日期：1970-11-01 00:00:00

abstract：:The phosphoprotein (P protein) of respiratory syncytial virus (RSV) is a key component of the viral RNA-dependent RNA polymerase complex. The protein is constitutively phosphorylated at the two clusters of serine residues (116, 117, and 119 [116/117/119] and 232 and 237 [232/237]). To examine the role of phosphorylati...

journal_title：Journal of virology

authors： Lu B,Ma CH,Brazas R,Jin H

更新日期：2002-11-01 00:00:00

abstract：:The bovine leukemia virus (BLV) is an oncogenic retrovirus that is associated with the development of persistent lymphocytosis (PL) and lymphoma in cattle. While B lymphocytes have been shown to be the primary cellular target of BLV, recent studies suggest that some T lymphocytes and monocytes may be infected by the v...

journal_title：Journal of virology

authors： Mirsky ML,Olmstead CA,Da Y,Lewin HA

更新日期：1996-04-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection is the most common opportunistic infection in immunosuppressed individuals, such as transplant recipients or people living with HIV/AIDS, and congenital CMV is the leading viral cause of developmental disabilities in infants. Due to the highly species-specific nature of CMV, animal mode...

journal_title：Journal of virology

authors： Marsh AK,Willer DO,Ambagala AP,Dzamba M,Chan JK,Pilon R,Fournier J,Sandstrom P,Brudno M,MacDonald KS

更新日期：2011-12-01 00:00:00

abstract：:The cellular immune response contributes to viral clearance as well as to liver injury in acute and chronic hepatitis C virus (HCV) infection. An immunodominant determinant frequently recognized by liver-infiltrating and circulating CD8(+) T cells of HCV-infected patients is the HCV(NS3-1073) peptide CVNGVCWTV. Using ...

journal_title：Journal of virology

authors： Wedemeyer H,Mizukoshi E,Davis AR,Bennink JR,Rehermann B

更新日期：2001-12-01 00:00:00

abstract：:The transcriptional activities of the four hepatitis B virus promoters were compared in three differentiated hepatoma cell lines, HepG2, Hep3B, and PLC/PRF/5; a dedifferentiated subline of HepG2, HepG2.1; a human cervical carcinoma cell line, HeLa S3; and a mouse fibroblast cell line, NIH 3T3. The plasmid constructs, ...

journal_title：Journal of virology

authors： Raney AK,Milich DR,Easton AJ,McLachlan A

更新日期：1990-05-01 00:00:00

abstract：:We have previously demonstrated that two mouse cell lines that are poorly infectible by reovirus become highly susceptible upon transfection with the gene encoding the epidermal growth factor receptor (EGFR) (J. E. Strong, D. Tang, and P. W. K. Lee, Virology 197:405-411, 1993). This enhancement of infection efficiency...

journal_title：Journal of virology

authors： Strong JE,Lee PW

更新日期：1996-01-01 00:00:00

abstract：:The DNA sequence of 3,240 nucleotides of the XbaI G fragment located in the unique long (UL) region of the equine herpesvirus 1 genome revealed two major open reading frames (ORFs) designated UL3 and UL4. The UL3 ORF of 470 amino acids (aa) maps at nucleotides (nt) 4450 to 3038 from the long terminus, and its predicte...

journal_title：Journal of virology

authors： Zhao Y,Holden VR,Harty RN,O'Callaghan DJ

更新日期：1992-09-01 00:00:00

abstract：:Expression of human papillomavirus late genes encoding L1 and L2 capsid proteins is restricted to terminally differentiated epithelial cells. We have previously identified and characterized an AU-rich, cis-acting negative regulatory element in the 3' untranslated region of human papillomavirus type 1 late mRNAs. This ...

journal_title：Journal of virology

authors： Zhao C,Tan W,Sokolowski M,Schwartz S

更新日期：1996-06-01 00:00:00

abstract：:Accumulated evidence demonstrates that Japanese encephalitis virus (JEV) infection triggers endoplasmic reticulum (ER) stress and neuron apoptosis. ER stress sensor protein kinase R-like endoplasmic reticulum kinase (PERK) has been reported to induce apoptosis under acute or prolonged ER stress. However, the precise r...

journal_title：Journal of virology

authors： Wang Q,Xin X,Wang T,Wan J,Ou Y,Yang Z,Yu Q,Zhu L,Guo Y,Wu Y,Ding Z,Zhang Y,Pan Z,Tang Y,Li S,Kong L

更新日期：2019-08-13 00:00:00

abstract：:After rabies virus glycoprotein was treated with CNBr, the peptide mixture was fractionated by preparative sodium dodecyl sulfate-polyacrylamide gel electrophoresis. CNBr-cleaved peptide fragments were resolved into seven peptide bands under reducing conditions and six peptide bands under nonreducing conditions. The i...

journal_title：Journal of virology

authors： Dietzschold B,Wiktor TJ,Macfarlan R,Varrichio A

更新日期：1982-11-01 00:00:00

abstract：UNLABELLED:We have recently shown in both herpesviruses and phages that packaged viral DNA creates a pressure of tens of atmospheres pushing against the interior capsid wall. For the first time, using differential scanning microcalorimetry, we directly measured the energy powering the release of pressurized DNA from th...

journal_title：Journal of virology

authors： Bauer DW,Li D,Huffman J,Homa FL,Wilson K,Leavitt JC,Casjens SR,Baines J,Evilevitch A

更新日期：2015-09-01 00:00:00

abstract：:Dengue virus (DV) infection can cause either a self-limiting flu-like disease or a threatening hemorrhage that may evolve to shock and death. A variety of cell types, such as dendritic cells, monocytes, and B cells, can be infected by DV. However, despite the role of T lymphocytes in the control of DV replication, the...

journal_title：Journal of virology

authors： Silveira GF,Wowk PF,Cataneo AHD,Dos Santos PF,Delgobo M,Stimamiglio MA,Lo Sarzi M,Thomazelli APFS,Conchon-Costa I,Pavanelli WR,Antonelli LRV,Báfica A,Mansur DS,Dos Santos CND,Bordignon J

更新日期：2018-04-27 00:00:00

abstract：:Glycoproteins homologous to glycoprotein B (gB) of herpes simplex virus constitute the most highly conserved group of herpesvirus glycoproteins. This strong conservation of amino acid sequences might be indicative of a common functional role. Indeed, gB homologs have been implicated in the processes of viral entry and...

journal_title：Journal of virology

authors： Kopp A,Mettenleiter TC

更新日期：1992-05-01 00:00:00

abstract：:Hepatitis C Virus (HCV) NS4B protein induces a specialized membrane structure which may serve as the replication platform for HCV RNA replication. In the present study, we demonstrated that NS4B has lipid modifications (palmitoylation) on two cysteine residues (cysteines 257 and 261) at the C-terminal end. Site-specif...

journal_title：Journal of virology

authors： Yu GY,Lee KJ,Gao L,Lai MM

更新日期：2006-06-01 00:00:00

abstract：:An in vitro system for production of hepatitis B virus (HBV) was established by infection of human hepatoma (HepG2) cells. HBV particles obtained from the serum of a chronic hepatitis B surface antigen (subtype ad) carrier were used to inoculate HepG2 cells. HBV envelope and core proteins were synthesized de novo by t...

journal_title：Journal of virology

authors： Bchini R,Capel F,Dauguet C,Dubanchet S,Petit MA

更新日期：1990-06-01 00:00:00

abstract：:Humans develop polyclonal, serotype-specific neutralizing antibody responses after dengue virus (DENV) infection. Many mouse antibodies that neutralize DENV bind to the lateral ridge or A strand epitopes on domain III of the viral envelope (EDIII) protein. It has been assumed that these epitopes are also the main targ...

journal_title：Journal of virology

authors： Wahala WM,Huang C,Butrapet S,White LJ,de Silva AM

更新日期：2012-04-01 00:00:00