Lesch-Nyhan syndrome.

Abstract:

:Three cases of severe involvement of the kidney with calculi in patients with the Lesch-Nyhan syndrome are presented. Two patients have radiolucent uric acid calculi. The biochemistry and pathology of the Lesch-Nyhan syndrome is discussed. Mechanisms in one family is traced over five generations. Although this syndrome is rare, the possibility of its existence must be entertained in patients with retardation and arthritis.

journal_name

Urology

journal_title

Urology

authors

Morton WJ

doi

10.1016/0090-4295(82)90124-8

subject

Has Abstract

pub_date

1982-11-01 00:00:00

pages

506-9

issue

5

eissn

0090-4295

issn

1527-9995

pii

0090-4295(82)90124-8

journal_volume

20

pub_type

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