Abstract:
:Sera from patients with multiple sclerosis (MS), patients with neurologic diseases other than MS, controls (adult and newborn), and rabbits immunized with bovine oligodendrocytes were assayed for antioligodendrocyte antibodies by a binding test with 125I-protein A. The mean binding of 125I-protein A to oligodendrocytes was similar in MS and non-MS sera, but both were significantly higher than binding in controls. A hundredfold increase of 125I-protein A binding over the preimmune value was obtained with a rabbit antioligodendrocyte antiserum. Oligodendrocyte-binding antibodies measured with 125I-protein A do not appear to be a distinctive feature of MS.
journal_name
Neurologyjournal_title
Neurologyauthors
Steck AJ,Regli Fdoi
10.1212/wnl.30.5.540subject
Has Abstractpub_date
1980-05-01 00:00:00pages
540-2issue
5eissn
0028-3878issn
1526-632Xjournal_volume
30pub_type
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