Abstract:
:Lactic acid is a platform chemical with various industrial applications, and its derivative, calcium lactate, is an important food additive. Fermentation coupled with in situ product removal (ISPR) can provide more outputs with high productivity. The method used in this study was based on calcium lactate crystallization. Three cycles of crystallization were performed during the fermentation course using a Bacillus coagulans strain H-1. As compared to fed-batch fermentation, this method showed 1.7 times higher average productivity considering seed culture, with 74.4% more L-lactic acid produced in the fermentation with ISPR. Thus, fermentation coupled with crystallization-based ISPR may be a biotechnological alternative that provides an efficient system for production of calcium lactate or lactic acid.
journal_name
Bioresour Technoljournal_title
Bioresource technologyauthors
Xu K,Xu Pdoi
10.1016/j.biortech.2014.04.002subject
Has Abstractpub_date
2014-07-01 00:00:00pages
33-9eissn
0960-8524issn
1873-2976pii
S0960-8524(14)00471-4journal_volume
163pub_type
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