A practical approach to disorders of hemostasis.

abstract：:Severe myocardial ischemia and infarction cause release of catecholamines, with exposure of injured myocardial cells to relatively high concentrations during the transitional period in which myocyte injury worsens. In experimental animals, the number of beta-adrenergic receptors increases markedly without any change i...

journal_title：Postgraduate medicine

authors： Willerson JT,Buja LM

更新日期：1988-02-29 00:00:00

abstract：:Evidence from epidemiologic, lipid intervention, and coronary angiographic studies demonstrates the importance of high-density lipoprotein cholesterol (HDL-C) in coronary artery disease (CAD) risk. Data from these studies strongly support the measurement of HDL-C in all patients screened for CAD. Patients with low lev...

journal_title：Postgraduate medicine

authors： Lavie CJ,O'Keefe JH,Blonde L,Gau GT

更新日期：1990-05-15 00:00:00

abstract：:No single therapeutic agent has been found to be universally effective for rheumatoid arthritis, so regimens using combinations of drugs have become the rule. Recently, several new agents with unique mechanisms of action have been introduced and found to produce various degrees of clinical benefit. Among these agents ...

journal_title：Postgraduate medicine

authors： Fye KH

更新日期：1999-10-01 00:00:00

abstract：:Management of the acutely poisoned patient should start with decontamination of the skin and irrigation of the eyes, if necessary, and assessment of cardiorespiratory status, neurologic status, and pupils and eye movement. If a definable toxic syndrome is present, the specific "antidote" should be given. If no such sy...

journal_title：Postgraduate medicine

authors： Saxena K,Kingston R

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVES:We investigated whether there was a higher prevalence of cognitive impairment (CI) and/or physical frailty (PF) in persons with diabetes compared to their non-diabetic counterparts, and the individual and combined impact of CI and PF on functional and mortality outcomes among diabetic older persons. METHOD:...

journal_title：Postgraduate medicine

authors： Thein FS,Li Y,Nyunt MSZ,Gao Q,Wee SL,Ng TP

更新日期：2018-08-01 00:00:00

abstract：:The cultural drive to be thin can lead to eating disorders in many women and girls. In adolescent females with diabetes, the increased focus on eating and the weight gain associated with good glycemic control likely increase their susceptibility to abnormal eating. It is clear that nonspecified and subthreshold eating...

journal_title：Postgraduate medicine

authors： Hoffman RP

更新日期：2001-04-01 00:00:00

abstract：:Therapy for osteomyelitis requires a multidisciplinary approach. A precise microbiologic diagnosis and adequate debridement of necrotic tissue are essential. Acute hematogenous osteomyelitis usually responds to antimicrobial therapy. The presence of an abscess or a metaphyseal cavity in hematogenous osteomyelitis and ...

journal_title：Postgraduate medicine

authors： Bamberger DM

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVES:As the prevalence of peripheral artery disease (PAD) increases there is growing concern about the associated healthcare burden. This burden has not been well-characterized in high-risk patients with concurrent diabetes and/or acute coronary syndrome (ACS). The objective of this analysis was to assess comorbi...

journal_title：Postgraduate medicine

authors： Reed Chase M,Friedman HS,Navaratnam P,Heithoff K,Simpson RJ Jr

更新日期：2016-01-01 00:00:00

abstract：:Many aspects of Kawasaki syndrome remain a mystery. The cause of the disease has eluded researchers, and its pathophysiology is a subject of much debate. However, the diagnostic features have been identified: A significant fever for at least 5 days, bilateral nonexudative conjunctivitis, erythema of the palms and sole...

journal_title：Postgraduate medicine

authors： Applegate BL

更新日期：1995-02-01 00:00:00

abstract：:The best treatment for adenocarcinoma of the prostate depends on the patient's age, general medical condition, life expectancy, and willingness to accept such side effects as impotence. Radical prostatectomy or full-dose radiation therapy are usually curative when cancer is confined to the gland. The technique of pros...

journal_title：Postgraduate medicine

authors： Soloway MS

更新日期：1988-11-15 00:00:00

abstract：:The dose and dosing interval for leukotriene receptor antagonists montelukast and zafirlukast in adult asthmatic patients were determined by bronchoprovocation with exercise or leukotriene D4 inhalation. Subsequent dose-ranging studies confirmed that once-daily ingestion of a 10-mg dose of montelukast was effective an...

journal_title：Postgraduate medicine

authors： Hendeles L

更新日期：2000-09-15 00:00:00

abstract：:Severe gastroesophageal reflux disease is usually a chronic problem with periods of relapse, but effective medical and surgical therapies are available. Two recently introduced agents, omeprazole (Prilosec) and cisapride (Propulsid), represent advances in medical therapy; the safety of long-term, continuous omeprazole...

journal_title：Postgraduate medicine

authors： Marshall JB

更新日期：1995-05-01 00:00:00

abstract：:A 65-year-old woman was hospitalized several times after having an acute anteroseptal transmural infarction. Her course was complicated by recurrent ventricular tachycardia and severe left ventricular failure. Chest x-ray films showed pulmonary congestion and mild right pleural effusion. Two-dimensional echocardiograp...

journal_title：Postgraduate medicine

authors： Cheng TC

更新日期：1982-10-01 00:00:00

abstract：:The diagnostic survey of the infertile couple usually takes about three months. After semen analysis, the husband is referred for general and urologic examination. The wife is given a general physical and pelvic examination and returns during the next two months for ovulation studies. Tubal patency tests are also perf...

journal_title：Postgraduate medicine

authors： Cohen MR

更新日期：1977-10-01 00:00:00

abstract：OBJECTIVES:Management of cardiovascular (CV) risk is an essential aspect of diabetes care, and acceptable CV risk is a requirement for antidiabetes medications. Dipeptidyl peptidase-4 (DPP-4) inhibitors effectively reduce glycated hemoglobin, with a low risk of hypoglycemia and weight gain. The purpose of this review i...

journal_title：Postgraduate medicine

authors： Ryan G

更新日期：2015-01-01 00:00:00

abstract：:Politicians may have written a temporary obituary for healthcare reform, but as anyone in medicine knows, reform is alive and (debatably) well. Mergers, acquisitions, and practice changes are happening all across the land, and many a physician is going from being a small-business owner to being an employee. Difficult ...

journal_title：Postgraduate medicine

authors： Rodeghero JA

更新日期：1994-11-15 00:00:00

abstract：:Pregnancy is an important risk factor for venous thrombosis, and venous thromboembolism is a leading cause of preventable death in pregnancy. Diagnosis of venous thromboembolism is complicated in that the symptoms of dyspnea and lower extremity edema are relatively common complaints of pregnant patients. Physicians sh...

journal_title：Postgraduate medicine

authors： Sellman JS,Holman RL

更新日期：2000-09-15 00:00:00

abstract：OBJECTIVES:Our aim was to investigate the association of liver fibrosis and necroinflammation with HS in untreated young patients with chronic hepatitis B (CHB). MATERIALS AND METHODS:A retrospective study was conducted in a military hospital in Turkey. A total of 254 subjects with CHB were included in this study. The...

journal_title：Postgraduate medicine

authors： Karacaer Z,Okur G,Cermik H,Altun D

更新日期：2016-09-01 00:00:00

abstract：:As sex, drugs, and rock 'n' roll have given way to STDs, HIV, and AIDS, adolescent sex has become an increasingly high-risk behavior. Dr Kay strongly believes that primary care physicians can have a prominent role in educating teens and their parents about the consequences of premature sexual activity and in promoting...

journal_title：Postgraduate medicine

authors： Kay LE

更新日期：1995-06-01 00:00:00

abstract：:High blood pressure is unquestionably a risk factor for premature morbidity and mortality, especially from coronary artery disease and stroke. Risk of clinical manifestations of coronary artery disease increases dramatically if other risk factors, such as a history of cigarette smoking, hypercholesterolemia, left vent...

journal_title：Postgraduate medicine

authors： Borhani NO

更新日期：1989-11-01 00:00:00

abstract：:Bulimia nervosa is a common eating disorder among women. Sociocultural and interpersonal pressures are thought to be highly influential in the development of the syndrome. An association with depression has also been suggested. Recognizing bulimia nervosa is usually difficult, because patients are hesitant to reveal t...

journal_title：Postgraduate medicine

authors： Fitzgerald BA,Wright JH,Atala KD

更新日期：1988-08-01 00:00:00

abstract：:Preview Drug-induced aseptic meningitis is an unusual adverse reaction associated with a number of medications. In this report, the authors present a case related to use of trimethoprim- sulfamethoxazole and summarize the available data regarding various proposed mechanisms of drug-induced meningitis. The usual clinic...

journal_title：Postgraduate medicine

authors： Wong JG,Hathaway SC,Paat JJ,Paterson RW,Steele GH Jr

更新日期：1994-12-01 00:00:00

abstract：:Surgical intervention is usually indicated in reflux esophagitis when medical therapy fails to control symptoms. Since most patients with peptic esophagitis also have a sliding hiatal hernia, early procedures focused on hernia repair. Weakness of the lower esophageal sphincter is now known to be the pathogenetic mecha...

journal_title：Postgraduate medicine

authors： Woodward ER

更新日期：1977-02-01 00:00:00

abstract：:It is often difficult to determine the true extent of a burn, but most small thermal burns can be easily evaluated and managed by primary care physicians. In this article, the authors review the characteristics of different types of burns, describe those that require treatment in a burn center, and discuss appropriate...

journal_title：Postgraduate medicine

authors： Clayton MC,Solem LD

更新日期：1995-05-01 00:00:00

abstract：:In cases of unusual presentations, such as the three cases described here, gout or gouty arthritis may be misdiagnosed as rheumatoid arthritis, septic arthritis, or other rheumatic conditions and thus inappropriately treated. Microscopic analysis using compensated polarized light and culture of synovial fluid helps di...

journal_title：Postgraduate medicine

authors： Uy JP,Nuwayhid N,Saadeh C

更新日期：1996-07-01 00:00:00

abstract：:Acute cardiac events involving coronary symptoms, elevated enzyme levels, and electrocardiographic changes without the development of Q waves often result in higher rates of reinfarction and unstable angina than do more severe myocardial infarctions. The incidence of these non-Q wave events is on the rise, possibly be...

journal_title：Postgraduate medicine

authors： Tamberella MR 3rd,Warner JG Jr

更新日期：2000-02-01 00:00:00

abstract：:Immunization of infants and children is the most effective strategy for decreasing the incidence of some infectious diseases. Most invasive disease due to Haemophilus influenzae type b occurs before age 5 years, and routine vaccination of infants for hepatitis B is currently recommended because selective immunization ...

journal_title：Postgraduate medicine

authors： Vetter RT,Johnson GM

更新日期：1995-11-01 00:00:00

abstract：:Regular aerobic exercise has significant cardiovascular benefits, including a reduction in incidence of and mortality from coronary artery disease--probably because of positive effects on blood lipid levels and blood pressure. Aerobic exercise can also be an important adjunct to a weight-loss program. Many persons who...

journal_title：Postgraduate medicine

authors： Mersy DJ

更新日期：1991-07-01 00:00:00

abstract：:Pneumococcal disease, which includes pneumococcal pneumonia, meningitis, and bacteremia, is associated with substantial morbidity, mortality, and health care costs in adults. Advanced age, chronic lung or cardiovascular disease, immunosuppressive conditions, and smoking increase the risk for infection. Despite the ava...

journal_title：Postgraduate medicine

authors： Rehm SJ,Farley MM,File TM Jr,Hall WJ,Hopkins R,Levine OS,Nichol KL,Nuorti P,Zimmerman RK,Schaffner W

更新日期：2009-11-01 00:00:00

abstract：:Type 2 diabetes, which is increasing in prevalence, is a multifaceted disease that presents a challenge to the primary care physician. In this article, Drs Flemmer and Vinik review the significant findings of several important clinical trials and present a method of comprehensive staged management to improve the quali...

journal_title：Postgraduate medicine

authors： Flemmer MC,Vinik AI

更新日期：2000-05-01 00:00:00