Abstract:
PURPOSE:The aim of this study was to determine the incidence of gastroschisis-related complications (GRCs) after closure of the abdominal wall defect, with a focus on frequency, type and timing of required surgical interventions, and to identify the impact of these on further outcome. METHODS:All gastroschisis patients treated from 1975 to 2008 in a tertiary-level center were retrospectively reviewed. Surgical procedures for GRCs following abdominal wall closure of simple gastroschisis [SG (intact continuous bowel)] and complex gastroschisis [CG (additional gastrointestinal malformations)] were compared, and outcomes were determined. RESULTS:One hundred and eight patients were identified with a median follow-up of 15.0 years (range 4-37). Ninety-four (87%) had SG, and 14 (13%) CG. Surgical interventions for GRCs were performed in 28 (26%) patients with 16 requiring multiple operations. Overall, 60 surgical procedures were performed. Bowel obstruction (n = 34) was the most common GRC, followed by anastomotic stricture (n = 8) and ischemic bowel (n = 3). The median interval between gastroschisis closure and secondary surgery for GRCs was 62.5 days (range 1 day-15 years). Surgical interventions were significantly more frequent in CG compared with SG [12/14 (86%) vs. 16/94 (17%); P < 0.0001]. The overall survival rate was 90%. Significantly, more patients required parenteral nutrition for more than 28 days [9/28 (32%) vs. 13/80 (16 %); P = 0.0468], longer median time to achieve full enteral feedings (87 vs. 33 days; P < 0.0001) and longer median hospital stay (117 vs. 54 days; P < 0.0001) compared with those not requiring additional surgery. CONCLUSION:GRCs requiring surgical interventions were more common in patients with CG, which were associated with delay in achieving full enteral feedings and prolonged hospital stay.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Friedmacher F,Hock A,Castellani C,Avian A,Höllwarth MEdoi
10.1007/s00383-014-3500-3subject
Has Abstractpub_date
2014-06-01 00:00:00pages
615-20issue
6eissn
0179-0358issn
1437-9813journal_volume
30pub_type
杂志文章abstract::Our presentation of four cases demonstrates the essential features of limb-body wall complex (LBWC), representing a compound anomaly pattern in body-wall defects. The diagnosis of this entity is based on two of the three following characteristics: (1) exencephaly/encephalocele and facial clefts; (2) thoraco- and/or ab...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000497
更新日期:2001-07-01 00:00:00
abstract::Recently, most studies reported magnesium as a N-methyl-D-aspartate receptor antagonist and its analgesic and perioperative anaesthetic effects have been discussed with central desensitization pathway. We investigated the effects of caudal ropivacaine plus magnesium and compared with ropivacaine alone on postoperative...
journal_title:Pediatric surgery international
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00383-006-1779-4
更新日期:2007-02-01 00:00:00
abstract:INTRODUCTION:Hepatoportoenterostomy (HPE) with the Kasai procedure is the treatment of choice for biliary atresia (BA) as the initial surgery. However, the appropriate level of dissection level of the fibrous cone (FC) of the porta hepatis (PH) is frequently unclear, and the procedure sometimes results in unsuccessful ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3799-4
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:Human pigmented tissue-engineered skin substitutes represent an advanced therapeutic option to treat skin defects. The inflammatory response is one of the major factors determining integration and long-term survival of such a graft in vivo. The aim of the present study was to investigate the spatiotemporal dist...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3616-5
更新日期:2014-12-01 00:00:00
abstract:AIM:An experimental study was performed to investigate the efficacy of colchicine in the prevention of fibrosis in the alkaline burn of the esophagus in rats. METHOD:A standard esophageal alkaline burn was produced by the application of 37.5% NaOH for a period of 90 s to the distal esophagus followed by a water rinse....
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1644-5
更新日期:2006-04-01 00:00:00
abstract::Intestinal neuronal dysplasia is a controversial form of dysganglionosis that has been described both as an isolated disorder and in association with Hirschsprung's disease. It has been blamed for the bad outcome of bowel function in patients operated on for Hirschsprung's disease. According to various authors, intest...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-1035-0
更新日期:2003-12-01 00:00:00
abstract::The n-3 and n-6 polyunsaturated fatty acids (PUFAs) are essential dietary constituents. They are important as a source of energy, as structural components of cell membranes, and as signalling molecules. They have been demonstrated to be potent modulators of the immune response, and research has endeavoured to optimise...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-005-1385-x
更新日期:2005-05-01 00:00:00
abstract::Recent studies of testicular descent suggest not only that the gubernaculum does not initially attach to the scrotum, but also that it must migrate from the groin. Two findings suggest that the gubernaculum may behave like an embryonic limb bud during this phase. First, the active growth centre is at the distal tip of...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-007-1907-9
更新日期:2007-07-01 00:00:00
abstract::Intestinal mucosal injury of various degrees occurs in many clinical situations and is initially evidenced by altered mucosal permeability. The latter may be assessed in animal models by determination of plasma-to-intestinal lumen clearance of specific molecules, usually chromated 51Cr EDTA. The purpose of this study ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050261
更新日期:1998-03-01 00:00:00
abstract::Glicentin, the main component of enteroglucagon, has trophic effects on intestinal mucosa. It may also have an inhibitory effect on extraintestinal invasion of enteric bacteria. We have established an in vitro bioassay system for determining the effects of recombinant human glicentin on bacterial internalization by co...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-1895-9
更新日期:2007-06-01 00:00:00
abstract::We examined immunohistochemically the expression and localisation of synapse-associated proteins, syntaxin (SNT) and synaptotagmin (STG) in the entire resected specimens of colon obtained at the time of pull-through operation from 15 patients with Hirschsprung's disease (HD) and 6 age-matched controls. Both antibodies...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050408
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:Variation exists in the diagnostic testing for gastroesophageal reflux (GER) in infants and in the application of surgical therapy. There has been an increase in antireflux surgery (ARS) since the development of laparoscopy but the outcomes in high-risk infants is unclear. This study examines the results of ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4281-x
更新日期:2018-07-01 00:00:00
abstract::In a retrospective study, intraoperative photos and video documentations of 884 children demonstrate that inguinal hernias and their recurrences are aspects of a full spectrum, which ranges from fully closed internal inguinal rings (IIR) and small openings to all-the way-down-into-the-scrotum open processus; 92% of th...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2018-3
更新日期:2007-12-01 00:00:00
abstract::Inflammatory pseudotumors (IPT) are uncommon mass lesions arising most typically in the lungs of young adults. These tumors are so named because of the difficulty in distinguishing them preoperatively from malignant lesions. IPT are characterized histologically by localized fibrous proliferations with infiltration by ...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s003830000518
更新日期:2001-09-01 00:00:00
abstract::The use of a silo for temporary coverage of exposed viscera for newborns with gastroschisis has allowed gradual reduction of the externalized intestine into the abdominal cavity. However, there has not been an easy way to monitor blood perfusion to the intestine within the silo other than with visual examination. In a...
journal_title:Pediatric surgery international
pub_type: 临床试验,杂志文章
doi:10.1007/s00383-006-1726-4
更新日期:2006-09-01 00:00:00
abstract::The introduction of posterior sagittal anorectoplasty (PSARP) by deVries and Peña in the early 80s has impacted to the treatment of patients with anorectal malformations (ARM). It gained great recognition worldwide in a very short time, and since then, surgeons dealing with the treatment of this complex malformation c...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-020-04629-9
更新日期:2020-04-01 00:00:00
abstract::In many very-low-birth-weight (VLBW) infants the ductus arteriosus fails to close spontaneously, and they subsequently develop signs and symptoms of poor tissue perfusion and heart failure. This study evalutes the results of early surgical closure of patent ductus arteriosus (PDA). We retrospectively reviewed the reco...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000515
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:Eosinophilic gastrointestinal disorders are rare in children and present with a broad spectrum of non-specific symptoms. To date, no guidelines for diagnosis, therapy and follow-up are validated. Aim of our study is to focus on eosinophilic colitis (EC), to determine a possible correlation between associated di...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-020-04832-8
更新日期:2021-01-07 00:00:00
abstract::The use of ureteric stents in reimplantation surgery is important. The younger the patient, the more important the stenting of ureters post reimplantation becomes, because even minimal oedema following surgery will produce ureteric obstruction unless stents are in place. JJ stents are now the preferred method of choic...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1205-8
更新日期:2004-05-01 00:00:00
abstract::Coagulopathies associated with malignancies are not extremely rare, but are uncommonly associated with Wilms' tumour (WT). A 6-month-old female with a WT and an abnormal coagulation profile is reported. Due to the Coagulopathy and elevated D-dimers in the blood, surgery was deferred and chemotherapy was given, after w...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0853-9
更新日期:2003-06-01 00:00:00
abstract::Modern plastic and reconstructive surgery continues to significantly improve the functional and aesthetic post-burn sequelae in children. It has become a major factor in restoring mobility, aesthetic appearance, self-esteem, and quality of life. The entire spectrum of plastic reconstructive procedures should be availa...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/BF01076930
更新日期:1997-07-01 00:00:00
abstract::In the last 2 years, 29 children with nocturnal enuresis were treated in the outpatient departments of the Departments of Urology and Pediatric Surgery of the Aristotle University, Thessaloniki. There were 22 boys and 7 girls aged 7 to 12 years. The clinical examination was normal in all cases. All children had underg...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050317
更新日期:1998-04-01 00:00:00
abstract:BACKGROUND:Pediatric surgeons and patient organisations agree that fewer centers for anorectal malformations with larger patient numbers are essential to reach better treatment. The European Union transacts a political process which aims to realize such centers of expertise for a multitude of rare diseases. All the cen...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3752-6
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:The aim of this study was to determine if the placement of prophylactic drains influences the incidence of postoperative adverse events in neonates. METHODS:Neonatal patients undergoing laparotomy between April 2000 and December 2007 were prospectively assigned to aggressive peritoneal cavity lavage, without t...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-011-2905-5
更新日期:2011-09-01 00:00:00
abstract::To assess the outcome of ureterocystoplasty (UCP) with renal preservation in infants, three infants had a UCP with preservation of the ipsilateral kidney, including one who had a ureteropyeloplasty and one who had a UCP using a previously reimplanted ureter. All three had complication-free improvement in bladder volum...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00183749
更新日期:1996-03-01 00:00:00
abstract:PURPOSE:Laparoscopic-assisted anorectoplasty (LAARP) is considered to benefit the patients with vesico-prostatic fistula. The aim of this study is to present the details of our LAARP technique for improving the short- and long-term outcomes in the patients with high and intermediate types of anorectal malformations (AR...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-019-04614-x
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:The Mac-2-binding protein glycosylation-modified isomer (M2BPGi) is a new marker for progression of hepatic fibrosis. We examined the relationship between serum M2BPGi levels and liver histological findings in patients with biliary atresia (BA) who were not transplant candidates. METHODS:Patients with BA who w...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4317-2
更新日期:2018-10-01 00:00:00
abstract::The activity of phospholipase A2 (PLA2) is elevated in the intestinal epithelia of patients with inflammatory bowel disease (IBD). We recently reported that PLA2 mediates hydrolysis of phosphatidylcholine (PC) to lysophosphatidylcholine (L-PC) when both are applied to the apical surface of cultured EC monolayers, resu...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830100592
更新日期:2001-05-01 00:00:00
abstract::Between 1974 and 1988, 86 newborns with perforated necrotizing enterocolitis (NEC) were treated by either laparotomy (usually involving a bowel resection and a temporary stoma) or a peritoneal drain under local anesthesia. The survival of babies in the laparotomy group was 57% versus 59% in the drained group. However,...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:
更新日期:1997-02-01 00:00:00
abstract:PURPOSE:We performed a systematic review and meta-analysis to compare the efficacy and safety between single-incision, transscrotal orchidopexy, and the traditional inguinal orchidopexy in children. METHODS:A systematic search of the electronic databases was conducted to identify studies compared the transscrotal orch...
journal_title:Pediatric surgery international
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00383-016-3956-4
更新日期:2016-10-01 00:00:00