Pulmonary thromboembolism. 1. Current concepts in pathogenesis and diagnosis.

Abstract:

:Thrombosis results from the dynamic interaction of venous stasis, hypercoagulability, and endothelial injury. Protection against thrombosis may be lost if there is deficiency of any of the factors that mediate platelet deaggregation, block fibrin deposition, or initiate fibrinolysis. A thrombus lodged in the pulmonary arterial circulation may remain hemodynamically and clinically silent or produce hemodynamic, clinical, and radiographic alterations. Although no signs and symptoms are specific to the condition, pulmonary thromboembolism can be diagnosed clinically if predisposing factors are taken into consideration. Diagnostic procedures include contrast venography, right heart catheterization, ventilation/perfusion lung scanning, and pulmonary angiography.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Giudice JC,Komansky HJ,Gordon R

doi

10.1080/00325481.1980.11715447

subject

Has Abstract

pub_date

1980-05-01 00:00:00

pages

64-71, 74-5, 77

issue

5

eissn

0032-5481

issn

1941-9260

journal_volume

67

pub_type

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