Enhancement of metastasis development by BCG immunotherapy.

Abstract:

:When BALB/c mice bearing growing transplants of a syngeneic colon carcinoma--Colon Tumor 26 (CT 26)--were treated with Bacillus Calmette-Guerin (BCG), no effect on tumor growth rate or survival time was observed compared to untreated controls. However, after excision of primary tumor transplants, enhanced development of lung metastases was noted in the BCG-treated mice, resulting in both as increased mortality rate (from metastatic disease) and a shorter survival time.

journal_name

J Surg Oncol

authors

Colmerauer ME,Koziol JA,Pilch YH

doi

10.1002/jso.2930150307

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

235-41

issue

3

eissn

0022-4790

issn

1096-9098

journal_volume

15

pub_type

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