Five-month observation of persistent diabetic macular edema after intravitreal injection of Ozurdex implant.

abstract：:Early onset sepsis due to group B streptococcus leads to neonatal morbidity, increased mortality, and long-term neurological deficencies. Interaction between septicemic GBS and confluent monolayers of human coronary artery endothelial cells (HCAECs) was analyzed by genome wide expression profiling. In total, 124 genes...

journal_title：Mediators of inflammation

authors： Beyrich C,Löffler J,Kobsar A,Speer CP,Kneitz S,Eigenthaler M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Airway smooth muscle (ASM) is considered to be a target for mediators released during airway inflammation. AIMS:To investigate the expression of c-fos, a constituent of the transcription factor activator protein-1, in human ASM cells. In addition, to measure the release of interleukin (IL)-6 into the condit...

journal_title：Mediators of inflammation

authors： McKay S,Bromhaar MM,de Jongste JC,Hoogsteden HC,Saxena PR,Sharma HS

更新日期：2001-06-01 00:00:00

abstract：:The stalks of Polygonum hydropiper L. (PHL) have been traditionally used in clinical practice for thousands of years in China to treat various inflammatory diseases. However, little research has been conducted to investigate the anti-inflammatory effects of PHL on TNBS-induced intestinal inflammation in rats. The aim ...

journal_title：Mediators of inflammation

authors： Zhang W,Pan Y,Qu S,Wang D,Cheng S,Liu X

更新日期：2018-05-07 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2020/6947482.]. ...

journal_title：Mediators of inflammation

authors： Zhao Y,Wang J,Zhang M,Li P,Qi S,Lin W

更新日期：2020-11-21 00:00:00

abstract：:Background. Neutrophilic bronchial inflammation is a main feature of bronchiectasis, but not much is known about its relationship with other disease features. Aim. To compare airway inflammatory markers with clinical and functional findings in subjects with stable noncystic fibrosis bronchiectasis (NCFB). Methods. 152...

journal_title：Mediators of inflammation

authors： Dente FL,Bilotta M,Bartoli ML,Bacci E,Cianchetti S,Latorre M,Malagrinò L,Nieri D,Roggi MA,Vagaggini B,Paggiaro P

更新日期：2015-01-01 00:00:00

abstract：:CXCL8 displays several tumor-promoting effects. Targeting and/or lowering CXCL8 concentrations within the tumor microenvironment would produce a therapeutic benefit. Aim of this study was to test the effect of IFNγ on the basal and TNFα-stimulated secretion of CXCL8 in TCP-1 and BCPAP thyroid cancer cell lines (harbor...

journal_title：Mediators of inflammation

authors： Rotondi M,Coperchini F,Awwad O,Pignatti P,Di Buduo CA,Abbonante V,Magri F,Balduini A,Chiovato L

更新日期：2016-01-01 00:00:00

abstract：:The mechanisms underlying the recurrence of atrial fibrillation (AF) after radiofrequency catheter ablation (RFCA) are not well concerned. The study sought to explore the association between growth differentiation factor-15 (GDF-15) and the incidence of recurrent events among AF patients after the ablation procedure. ...

journal_title：Mediators of inflammation

authors： Wei Y,Liu S,Yu H,Zhang Y,Gao W,Cui M,Li L

更新日期：2020-08-21 00:00:00

abstract：:We investigated the influence of 2-chlorodeoxyadenosine (2-CdA) in combination with tumour necrosis factor-alpha (TNFalpha) or its mutein VI, which differs from the native molecule by N-terminal amino acid composition, on the survival time of mice inoculated with leukaemia L1210 or P388. Groups of mice with leukaemia ...

journal_title：Mediators of inflammation

authors： Góra-Tybor J,Warzocha K,Robak T

更新日期：1995-01-01 00:00:00

abstract：:Obesity is marked by chronic, low-grade inflammation. Here, we examined whether intrinsic differences between white and brown adipocytes influence the inflammatory status of macrophages. White and brown adipocytes were characterized by transcriptional regulation of UCP-1, PGC1α, PGC1β, and CIDEA and their level of IL-...

journal_title：Mediators of inflammation

authors： Dowal L,Parameswaran P,Phat S,Akella S,Majumdar ID,Ranjan J,Shah C,Mogre S,Guntur K,Thapa K,Gesta S,Vishnudas VK,Narain NR,Sarangarajan R

更新日期：2017-01-01 00:00:00

abstract：:Thiopurines are extensively used immunosuppressants for the treatment of inflammatory bowel disease (IBD). The polymorphism of thiopurine S-methyltransferase (TPMT) influences thiopurine metabolism and therapy outcome. We used a TPMT knockdown (kd) model of human Jurkat T-lymphocytes cells to study the effects of trea...

journal_title：Mediators of inflammation

authors： Misdaq M,Ziegler S,von Ahsen N,Oellerich M,Asif AR

更新日期：2015-01-01 00:00:00

abstract：:Little is known about Yu-Ping-Feng (YPF), a typical Chinese herbal decoction, for its antitumor efficacy in non-small-cell lung cancer (NSCLC). Here, we found that YPF significantly inhibited the growth of Lewis lung cancer, prolonged the survival of tumor-bearing mice, promoted NK cell tumor infiltration, increased t...

journal_title：Mediators of inflammation

authors： Luo Y,Wu J,Zhu X,Gong C,Yao C,Ni Z,Wang L,Ni L,Li Y,Zhu S

更新日期：2016-01-01 00:00:00

abstract：Aim:The objective of the current study is to analyze the correlation between cytokine levels and periodontal parameters in aggressive periodontitis patients before and after periodontal treatment that was performed by using two different laser therapies. Materials and Methods:Twenty-six generalized aggressive periodon...

journal_title：Mediators of inflammation

authors： Talmac AC,Calisir M,Eroglu EG,Ertugrul AS

更新日期：2019-06-12 00:00:00

abstract：Background:Gut microbiota is implied in obesity, because of its ability to harvest energy from diet, and in the regulation of behavior. Given the link between gut microbiota, body composition, obesity, and anxiety, the aim of this study was to evaluate the effects of a new psychobiotic formulation. Methods:Eligible pa...

journal_title：Mediators of inflammation

authors： Colica C,Avolio E,Bollero P,Costa de Miranda R,Ferraro S,Sinibaldi Salimei P,De Lorenzo A,Di Renzo L

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:In smoking COPD patients the bronchoalveolar lavage (BAL) fluid contains high numbers of inflammatory cells. These cells might produce arachidonic acid (AA) metabolites, which contribute to inflammation and an increased bronchomotor tone. AIMS:To investigate levels of AA metabolites in BAL fluid, before and...

journal_title：Mediators of inflammation

authors： Verhoeven GT,Garrelds IM,Hoogsteden HC,Zijlstra FJ

更新日期：2001-02-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) remains a high morbidity and mortality disease entity in critically ill patients, despite decades of numerous investigations into its pathogenesis. To obtain global protein expression changes in acute lung injury (ALI) lung tissues, we employed a high-throughput proteomics me...

journal_title：Mediators of inflammation

authors： Liu D,Mao P,Huang Y,Liu Y,Liu X,Pang X,Li Y

更新日期：2014-01-01 00:00:00

abstract：:Causes of mortality from COVID-19 include respiratory failure, heart failure, and sepsis/multiorgan failure. TLR4 is an innate immune receptor on the cell surface that recognizes pathogen-associated molecular patterns (PAMPs) including viral proteins and triggers the production of type I interferons and proinflammator...

journal_title：Mediators of inflammation

authors： Aboudounya MM,Heads RJ

更新日期：2021-01-14 00:00:00

abstract：AIM:This study was undertaken in order to determine whether anti-inflammatory cytokine interleukin-10 is responsible for a previously described protection against Klebsiella infection mediated by antilipopolysaccharide antibodies. METHODS:BALB/c mice were infected intraperitoneally with a lethal challenge of Klebsiell...

journal_title：Mediators of inflammation

authors： Rukavina T,Ticac B,Vasiljev V

更新日期：2006-01-01 00:00:00

abstract：Aims:To assess the maresin 1 (MaR1) contents in type 2 diabetic patients with or without diabetic foot ulcer and to analyze the association of MaR1 concentrations with several metabolism-related parameters. Methods:Plasma MaR1 concentrations were analyzed in 96 subjects with normal glucose tolerant (NC, n = 43), type ...

journal_title：Mediators of inflammation

authors： Miao T,Huang B,He N,Sun L,Du G,Gong X,Xu Y,Zheng Y,Zheng H,Qu H

更新日期：2020-04-16 00:00:00

abstract：:Infection with dengue virus (DENV) causes an increase in proinflammatory responses, such as nitric oxide (NO) generation and TNF-α expression; however, the molecular mechanism underlying this inflammatory activation remains undefined, although the activation of the transcription factor NF-κB is generally involved. In ...

journal_title：Mediators of inflammation

authors： Cheng YL,Lin YS,Chen CL,Wan SW,Ou YD,Yu CY,Tsai TT,Tseng PC,Lin CF

更新日期：2015-01-01 00:00:00

abstract：:Monocyte and macrophage diversity is evidenced by the modulation of cell surface markers and differential production of soluble mediators. These immune cells play key roles in controlling tissue homeostasis, infections, and excessive inflammation. Macrophages remove dead cells in a process named efferocytosis, contrib...

journal_title：Mediators of inflammation

authors： Stunault MI,Bories G,Guinamard RR,Ivanov S

更新日期：2018-12-10 00:00:00

abstract：AIM:The aim of this study was to evaluate the presence of the cytokines tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) in human periapical lesions. SUBJECTS AND METHODS:Samples were obtained from three groups of teeth: symptomatic teeth, asymptomatic lesions, and uninflamed periradicular tissues as a...

journal_title：Mediators of inflammation

authors： Prso IB,Kocjan W,Simić H,Brumini G,Pezelj-Ribarić S,Borcić J,Ferreri S,Karlović IM

更新日期：2007-01-01 00:00:00

abstract：:The objective of this study was to evaluate the effects of peptides derived from synbiotics on improving inflammatory bowel disease (IBD). Five-week-old male C57BL/6 mice were administered with dextran sulfate sodium (DSS) via drinking water for seven days to induce IBD (IBD group). The mice in the IBD group were oral...

journal_title：Mediators of inflammation

authors： Ha J,Oh H,Oh NS,Seo Y,Kang J,Park MH,Kim KS,Kang SH,Yoon Y

更新日期：2020-07-04 00:00:00

abstract：:Edelweiss (Leontopodium alpinum Cass.) is traditionally employed in folk medicine as an anti-inflammatory remedy. In nature, the plant is sparsely available and protected; therefore production of callus cultures was established. A concentrated ethanolic extract of culture homogenate, with leontopodic acid representing...

journal_title：Mediators of inflammation

authors： Daniela L,Alla P,Maurelli R,Elena D,Giovanna P,Vladimir K,Roberto DT,Chiara de L,Saveria P,Liudmila K

更新日期：2012-01-01 00:00:00

abstract：:Human gingival fibroblast barrier dysfunction caused by inflammation contributes to gingivitis and can lead to inflammatory periodontal disease. The disease features include upregulated epithelial permeability, increased inflammatory mediators, and downregulated junctional complex molecules. Carbon monoxide- (CO-) rel...

journal_title：Mediators of inflammation

authors： Lv J,Liu Y,Jia S,Zhang Y,Tian H,Li J,Song H

更新日期：2020-04-28 00:00:00

abstract：INTRODUCTION:Proliferative vitreoretinopathy (PVR) is a severe inflammatory complication of retinal detachment. Pathological epiretinal membranes grow on the retina surface leading to contraction, and surgery fails in 5% to 10% of the cases. We evaluated the expression of VEGF-A, Otx1, Otx2, Otx3, and p53 family member...

journal_title：Mediators of inflammation

authors： Azzolini C,Pagani IS,Pirrone C,Borroni D,Donati S,Al Oum M,Pigni D,Chiaravalli AM,Vinciguerra R,Simonelli F,Porta G

更新日期：2013-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is one of the most common autoimmune diseases caused by abnormal immune activation and immune tolerance. Immunomodulatory cells (ICs) play a critical role in the maintenance and homeostasis of normal immune function and in the pathogenesis of RA. The human gastrointestinal tract is inhabited ...

journal_title：Mediators of inflammation

authors： Xu H,Zhao H,Fan D,Liu M,Cao J,Xia Y,Ju D,Xiao C,Guan Q

更新日期：2020-09-09 00:00:00

abstract：:The present study was carried out to investigate the effects and mechanisms of polydatin (PD) in septic mice. The model of cecal ligation and puncture (CLP-)induced sepsis was employed. Pretreatment of mice with PD (15, 45, and 100 mg/kg) dose-dependently reduced sepsis-induced mortality and lung injury, as indicated ...

journal_title：Mediators of inflammation

authors： Li XH,Gong X,Zhang L,Jiang R,Li HZ,Wu MJ,Wan JY

更新日期：2013-01-01 00:00:00

abstract：:Stimulation of phosphoinositide hydrolysis in myocardium from autoimmune myocarditis mice by ThEA and histamine was assayed. Myocardium from autoimmune heart, but not the normal forms, specifically increased phosphoinositide turnover in the presence of histaminergic agonists. This increment was blocked by a specific H...

journal_title：Mediators of inflammation

authors： Goren N,Leiros CP,Sterin-Borda L,Borda ES

更新日期：1993-01-01 00:00:00

abstract：:Paraoxonase 1 (PON1) activity is markedly influenced by coding polymorphisms, Q/R at position 192 and M/L at position 55 of the PON1 gene. We investigated the frequencies of these polymorphisms and their effects on PON1 and antioxidant activities in 844 South African mixed ancestry individuals. Genotyping was done usi...

journal_title：Mediators of inflammation

authors： Macharia M,Kengne AP,Blackhurst DM,Erasmus RT,Matsha TE

更新日期：2014-01-01 00:00:00

abstract：:Recent investigations have indicated that reactive metabolites and AGE-RAGE-mediated inflammation might play an important role in the pathogenesis of ischemia-reperfusion injury in liver transplantation. In this observational clinical study, 150 patients were enrolled following liver transplantation from deceased dono...

journal_title：Mediators of inflammation

authors： Brenner T,Fleming TH,Spranz D,Schemmer P,Bruckner T,Uhle F,Martin EO,Weigand MA,Hofer S

更新日期：2013-01-01 00:00:00