Topographical projection of the septal organ to the main olfactory bulb in rats: ontogenetic study.

Abstract:

:Using the horseradish peroxidase (HRP) retrograde tracing method, we have studied the topographical organization of the projection of the septal organ to the main olfactory bulb in rats varying in age from 22 fetal days up to 15 postnatal days. For all developmental stages studied, receptor cells of the septal organ had their axons ending in a relatively circumscribed region of the olfactory bulb, which was the posterior ventromedial bulbar aspect. In younger animals, olfactory receptor cells were observed within the epithelial area isolating the septal organ from the olfactory epithelium, whereas this area was reported to be an exclusive respiratory region in adult rats. The complete disappearance of these receptor cells noted in 12-day-old rats was related to some ontogenetic process.

journal_name

Brain Res

journal_title

Brain research

authors

Astic L,Saucier D

doi

10.1016/0165-3806(88)90248-9

subject

Has Abstract

pub_date

1988-08-01 00:00:00

pages

297-303

issue

2

eissn

0006-8993

issn

1872-6240

journal_volume

470

pub_type

杂志文章
  • Brain neuropeptide Y in the control of adrenocorticotropic hormone secretion in the dog.

    abstract::An immunoneutralization technique with specific antibodies was used to explore the role of endogenous neuropeptide Y (NPY) in the adrenocorticotropic hormone (ACTH) release after hypoglycemic stress in the dog. Dogs received injections of rabbit antihuman NPY gamma-globulin (anti-NPY) or normal gamma-globulin (NGG) in...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91369-r

    authors: Inui A,Inoue T,Nakajima M,Okita M,Sakatani N,Okimura Y,Chihara K,Baba S

    更新日期:1990-03-05 00:00:00

  • Transient elevation of intrasynaptosomal free calcium by putrescine.

    abstract::The role of polyamines in the regulation of free intrasynaptosomal Ca2+, [Ca2+]i was studied. After preincubation of rat brain synaptosomes with 5 mM difluormethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase, the K+-induced increase of [Ca2+]i was 33% less than that in non-treated synaptosome...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)91162-0

    authors: Komulainen H,Bondy SC

    更新日期:1987-01-13 00:00:00

  • The electrophysiological and morphological characteristics of feline dorsal root ganglion cells.

    abstract::The electrophysiological characteristics of physiologically typed L7 and S1 dorsal root ganglion (DRG) cells have been studied in the cat by intracellular recording. The injection of the fluorescent dye Lucifer Yellow has enabled us to study the morphology of these neurons. Our results show that over the entire range ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91391-0

    authors: Cameron AA,Leah JD,Snow PJ

    更新日期:1986-01-01 00:00:00

  • Motor experience with graspable objects reduces their implicit analysis in visual- and motor-related cortex.

    abstract::Motor-related regions of parietal and prefrontal cortices have been shown to selectively activate when observers passively view objects that afford manual grasping. Yet, it remains unknown whether these cortical responses depend on prior motor-related experience with the object being observed. To address this question...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.04.059

    authors: Handy TC,Tipper CM,Schaich Borg J,Grafton ST,Gazzaniga MS

    更新日期:2006-06-30 00:00:00

  • Calorie restriction attenuates astrogliosis but not amyloid plaque load in aged rhesus macaques: a preliminary quantitative imaging study.

    abstract::While moderate calorie restriction (CR) in the absence of malnutrition has been consistently shown to have a systemic, beneficial effect against aging in several animals models, its effect on the brain microstructure in a non-human primate model remains to be studied using post-mortem histopathologic techniques. In th...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2013.02.046

    authors: Sridharan A,Pehar M,Salamat MS,Pugh TD,Bendlin BB,Willette AA,Anderson RM,Kemnitz JW,Colman RJ,Weindruch RH,Puglielli L,Johnson SC

    更新日期:2013-05-01 00:00:00

  • Calcitonin gene-related peptide (hCGRP alpha) binding sites in the nucleus accumbens. Atypical structural requirements and marked phylogenic differences.

    abstract::The distribution of [125I]hCGRP alpha binding sites was studied in tissue sections from rat brain and, at the level of the nucleus accumbens in the brains of 6 other species. In the rat, very high levels of binding were found in the nucleus accumbens, the amygdaloid complex and mammillary body while high amounts were ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90686-p

    authors: Dennis T,Fournier A,Guard S,St Pierre S,Quirion R

    更新日期:1991-01-18 00:00:00

  • Effect of aspartame on N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain synaptic membranes.

    abstract::Aspartame (L-aspartyl-L-phenylalanine methyl ester), an artificial low-calorie sweetener, was shown to dose-dependently inhibit L-[3H]glutamate binding to its N-methyl-D-aspartate-specific receptors. L-Aspartic acid, a major endogenous metabolite of aspartame, inhibited the binding more stronger than aspartame, while ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91729-z

    authors: Pan-Hou H,Suda Y,Ohe Y,Sumi M,Yoshioka M

    更新日期:1990-06-18 00:00:00

  • Increase in acetylcholine release from chick embryo retina during development.

    abstract::The release of [3H]acetylcholine (ACh) from 6-, 8-, 10-, 12-, 14- and 16-day chick embryo neural retina layers was determined using a perfusion system to collect the released neurotransmitter. After labeling the tissue with [3H]choline, samples of [3H]ACh released before and after stimulation by 80 mM KCl or 5 mM glut...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0165-3806(82)90137-7

    authors: Thompson JM

    更新日期:1982-07-01 00:00:00

  • Alterations in monoamines and GABA in the ventromedial and paraventricular nuclei of the hypothalamus following cold exposure: a reduction in noradrenaline induces hyperphagia.

    abstract::A microdialysis technique for the in vivo assessment of the monoaminergic and GABAergic levels in the ventromedial (VMN) and paraventricular nuclei (PVN) of the hypothalamus was used in order to examine the activities of neurons that project to the hypothalamic regions and are implicated in the regulation of ingestive...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01796-5

    authors: Ohtani N,Sugano T,Ohta M

    更新日期:1999-09-18 00:00:00

  • Neuregulin 1 growth factors regulate proliferation but not apoptosis of a CNS neuronal progenitor cell line.

    abstract::Growth factor-dependent proliferation of neuronal progenitors is an essential stage in CNS development. Although several of these growth factors have been identified, high levels of neuregulin 1 (NRG1) mRNA and protein expression in the CNS during the time of neuronal progenitor expansion suggest NRG1 growth factors m...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.06.025

    authors: Edwards JM,Bottenstein JE

    更新日期:2006-09-07 00:00:00

  • Morphine microinjected into the nucleus raphe magnus does not block the activity of spinal trigeminal nucleus oralis convergent neurons in the rat.

    abstract::This study investigated the effects of morphine microinjection into the nucleus raphe magnus (RMg) on electrically evoked C-fiber activities of convergent neurons in the spinal trigeminal nucleus oralis (Sp5O), in halothane-anesthetized rats. Although the neurons could be depressed by systemic morphine (6 mg/kg, i.v.)...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)00659-3

    authors: Dualé C,Molat JL,Dallel R

    更新日期:1998-08-24 00:00:00

  • D2 inhibition of stimulated Fos immunoreactivity in cultured tyrosine hydroxylase-ir hypothalamic neurons.

    abstract::We have previously demonstrated that Fos immunoreactivity can be stimulated by KCl, forskolin or glutamate in cultured tyrosine hydroxylase-immunoreactive (TH-ir) hypothalamic neurons. The present study was performed to determine whether agents that regulate dopaminergic activity, particularly D1 and D2 receptor agoni...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)90711-0

    authors: Sim LJ,Selley DE,Tsai KP,Morris M

    更新日期:1994-07-18 00:00:00

  • Terminin (Tp 63/60), a novel cell senescence-related protein, is present in the aging human hippocampus.

    abstract::We have previously identified a cell senescence-related, detergent-insoluble cytoplasmic protein referred to as terminin, and have presented the development-dependent modification of terminin polypeptides in rat brain. In the present study, we characterize biochemically and immunocytochemically terminin expression in ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91679-9

    authors: Yang G,Wang E

    更新日期:1994-05-02 00:00:00

  • Time course of reinnervation of the olfactory bulb after transection of the primary olfactory nerve in the pigeon.

    abstract::Horseradish peroxidase (HRP) histochemistry was used to study the time course of reinnervation of the pigeon olfactory bulb after simple transection of the primary olfactory nerve. At selected intervals (9, 13, 29, 61 and 93 days) after transection of the right olfactory nerve, a concentrated solution of HRP was insti...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00361-s

    authors: Jennings RA,Hambright Keiger CJ,Walker JC

    更新日期:1995-06-19 00:00:00

  • Brain damage in a mouse model of global cerebral ischemia. Effect of NMDA receptor blockade.

    abstract::The importance of particular genes in neuronal death following global cerebral ischemia can readily be studied in genetically modified mice provided a reliable model of ischemia is available. For that purpose, we developed a mouse model of global cerebral ischemia that induces consistent damage to different regions of...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(03)03014-2

    authors: Olsson T,Wieloch T,Smith ML

    更新日期:2003-08-29 00:00:00

  • The responses of simultaneously recorded Purkinje cells to the perturbations of the step cycle in the walking ferret: a study using a new analytical method--the real-time postsynaptic response (RTPR).

    abstract::Experiments were performed in ambulating decerebrate ferrets to examine the activity of up to 6 simultaneously recorded Purkinje cells oriented sagittally during unperturbed and perturbed locomotion using a new analytical technique, the real-time postsynaptic response (RTPR), which permits a trial-by-trial assessment ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91646-x

    authors: Lou JS,Bloedel JR

    更新日期:1986-02-19 00:00:00

  • Astrocyte stellation in saline media lacking bicarbonate: possible relation to intracellular pH and tyrosine phosphorylation.

    abstract::Primary cultures of astrocytes exhibit a polygonal morphology, but on treatment with agents that increase cAMP they change to stellate cells. We found that astrocyte stellation also occurred on replacing the culture medium with saline buffered with HEPES. However, stellation did not occur when the medium was replaced ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(02)02819-6

    authors: Cechin SR,Gottfried C,Prestes CC,Andrighetti L,Wofchuk ST,Rodnight R

    更新日期:2002-08-09 00:00:00

  • Termination of a separate (proprioceptive?) cuneothalamic tract from external cuneate nucleus in monkey.

    abstract::The termination of a pathway recently discovered in monkey, from the external cuneate nucleus (ECN) to the thalamus, has been investigated with the degeneration method. A previous HRP study showed that the projection is crossed. The ECN fibers terminate a wedge-shaped zone located dorsally in the rostral half of the c...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90856-8

    authors: Boivie J,Boman K

    更新日期:1981-11-16 00:00:00

  • GABAA alpha 2 mRNA levels are decreased following induction of spontaneous epileptiform discharges in hippocampal-entorhinal cortical slices.

    abstract::Exposure of hippocampal slices to Mg2+ free media (0 Mg) has been shown to trigger full production of stimulus-induced seizure activity after restoration of physiological conditions [1]. In the present study employing hippocampal entorhinal cortical slices (HEC), spontaneous epileptiform discharges (SEDs) were induced...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(96)00060-1

    authors: Vick RS,Rafiq A,Coulter DA,Jakoi ER,DeLorenzo RJ

    更新日期:1996-05-20 00:00:00

  • Some connections of the area octavolateralis of Pleurodeles waltlii. A study with horseradish peroxidase under in vitro conditions.

    abstract::Horseradish peroxidase application in exsanguinated, pre-perfused newts, Pleurodeles waltlii, appeared to be very useful to study the connections of the area octavolateralis. Efferents from the octavolateral area course via bilateral lemnisci to the tectum and a presumptive torus semicircularis in the midbrain. Additi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)90859-6

    authors: Gonzalez A,Munoz M

    更新日期:1987-10-13 00:00:00

  • Differential expression of Fos protein after transection of the rat infraorbital nerve in the trigeminal nucleus caudalis.

    abstract::To determine the effects of nerve injury on Fos expression, temporal and spatial distributions of Fos-positive neurons in the trigeminal nucleus caudalis were examined after tissue injury for isolation of the infraorbital nerve as controls and transection of this nerve as well as noxious chemical stimulation by formal...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00633-1

    authors: Terayama R,Nagamatsu N,Ikeda T,Nakamura T,Rahman OI,Sakoda S,Shiba R,Nishimori T

    更新日期:1997-09-12 00:00:00

  • Therapeutic window of hyperbaric oxygen therapy for hypoxic-ischemic brain damage in newborn rats.

    abstract::Previous studies showed that hyperbaric oxygen (HBO) promoted cell proliferation in hypoxic-ischemic (HI) neonate rats. Neural stem cells (NSC) existed in the brain lifelong and can be activated. This study was undertaken to assess whether HBO treatment promoted the proliferation of NSC and repaired the brain damage r...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2008.05.016

    authors: Wang XL,Zhao YS,Yang YJ,Xie M,Yu XH

    更新日期:2008-07-30 00:00:00

  • Elevation of AKR7A2 (succinic semialdehyde reductase) in neurodegenerative disease.

    abstract::Elevated levels of oxidative stress or decreased antioxidant defense mechanisms may underlie the regionally increased oxidative damage to brain observed in many neurodegenerative disorders. Phase I detoxification pathways for reactive aldehydes generated from lipid peroxidation include aldehyde dehydrogenases, alcohol...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(01)02897-9

    authors: Picklo MJ Sr,Olson SJ,Hayes JD,Markesbery WR,Montine TJ

    更新日期:2001-10-19 00:00:00

  • Effects of diabetes mellitus on myenteric neuronal density and sodium channel expression in the rat ileum.

    abstract::Diabetes mellitus (DM) may lead to gastrointestinal motility disorders. Rodent models of DM indicate the presence of morpho-functional abnormalities of the enteric nervous system. Here, we evaluated whether experimental DM can cause changes in the excitatory cholinergic fibers, neuronal density, and voltage-gated sodi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2018.11.041

    authors: Brasileiro AD,Garcia LP,de Carvalho da Silva S,Rocha LB,Pedrosa AL,Vieira AS,da Silva VJD,Rodrigues ARA

    更新日期:2019-04-01 00:00:00

  • Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector.

    abstract::Safe, long-term gene expression is a primary criteria for effective gene therapy in the brain, so studies were initiated to evaluate adeno-associated virus (AAV) vector transfer of a reporter gene into specific sites of the rat brain. In the 4 day old rat, site infusions of AAV-CMV-lacZ (1 microliter; 5 x 10(4) partic...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)01488-8

    authors: McCown TJ,Xiao X,Li J,Breese GR,Samulski RJ

    更新日期:1996-03-25 00:00:00

  • Modulating effects of posttraining epinephrine on memory: involvement of the amygdala noradrenergic system.

    abstract::These experiments examined the effects, on retention, of posttraining intra-amygdala administration of norepinephrine (NE), and propranolol. Rats were trained on a one-trial step-through inhibitory avoidance task and tested for retention 24 h later. Injections were administered bilaterally (1.0 microliter/injection) t...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91049-8

    authors: Liang KC,Juler RG,McGaugh JL

    更新日期:1986-03-12 00:00:00

  • Identification and localization of cell types that express endothelial and neuronal nitric oxide synthase in the rat nucleus tractus solitarii.

    abstract::Numerous studies have suggested that nitric oxide (NO) in the nucleus tractus solitarii (NTS) participates in modulating cardiovascular function. Nitric oxide synthase (NOS), the enzyme responsible for synthesis of NO, exists in 3 isoforms: endothelial NOS (eNOS), neuronal NOS (nNOS), and inducible NOS (iNOS). Althoug...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.07.057

    authors: Lin LH,Taktakishvili O,Talman WT

    更新日期:2007-09-26 00:00:00

  • Cloning and expression of the neuromedin B receptor and the third subtype of bombesin receptor genes in the mouse.

    abstract::We cloned the genes for the mouse homologue of the neuromedin B receptor (NMB-R) and the bombesin receptor subtype 3 (BRS-3). Both receptor genes consist of three exons with well-conserved intron-exon borders. Although the NMB-R gene spans more than 10 kb, the BRS-3 gene spans only about 4 kb. Comparison of the mouse ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00380-6

    authors: Ohki-Hamazaki H,Wada E,Matsui K,Wada K

    更新日期:1997-07-11 00:00:00

  • Maternal and genetic factors in stress-resilient and -vulnerable rats: a cross-fostering study.

    abstract::Early environmental factors can modulate the development of the hypothalamic-pituitary-adrenal (HPA) axis response to stress, together with subsequent brain functions and emotional behaviors. Two rat strains, Sprague-Dawley (SD) and Fischer 344 (F344), are known to exhibit differences in HPA axis reactivity and anxiet...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.11.070

    authors: Uchida S,Hara K,Kobayashi A,Otsuki K,Hobara T,Yamagata H,Watanabe Y

    更新日期:2010-02-26 00:00:00

  • In vivo and in vitro labelling of perineuronal nets in rat brain.

    abstract::Previous lectin-histochemical and immunocytochemical investigations using fixed tissue revealed perineuronal nets as lattice-like accumulations of extracellular matrix proteoglycans at the surface of several types of neurons. In the present study, perineuronal nets in the rat brain were labelled for the first time in ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(96)00152-7

    authors: Brückner G,Bringmann A,Köppe G,Härtig W,Brauer K

    更新日期:1996-05-13 00:00:00