Activated sialidase activity in transformed lymphocytes by Epstein-Barr (EB) virus of sialidosis type I (cherry-red spot-myoclonus syndrome).

Abstract:

:We report a new Japanese family of sialidosis type I. The sialidase activity was deficient in the lymphocytes of 2 patients (6.8% (sister) and 12.5% (brother) of control mean). However, surprisingly, using the transformed lymphocytes by EB virus, this activity was activated to 51.7% (sister) and 49.5% (brother) of control mean, respectively. Although the mechanism for this activation was not known, we discussed the possible mechanisms for this phenomenon.

journal_name

J Neurol Sci

authors

Yamamoto M,Yamauchi T,Yamamoto K,Kobayashi T

doi

10.1016/0022-510x(95)00102-8

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

105-7

issue

1

eissn

0022-510X

issn

1878-5883

pii

0022510X95001028

journal_volume

131

pub_type

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