Abstract:
:T-lymphocyte proliferative responses were determined with peripheral blood lymphocytes (PBL), peritoneal exudate lymphocytes (PEL) and lymph node lymphocytes (LNL) of guinea pigs immunized with horse cytochrome c (HCytc). The proliferative response of PBL activated by peptide 81-104 from animals immunized with HCytc was equal to or better than HCytc while the proliferative response activated by peptide 1-65 was small and no reactivity was seen when peptide 66-80 was tested. In contrast, the proliferative responses of PEL and LNL stimulated by peptide 1-65 approached those activated by HCytc, while peptide 81-104 was far less effective. The differences in the proliferative responses of PBL and PEL activated by peptide 81-104 and peptide 1-65 suggest that different lymphoid compartments may have T-cells directed to different T-cell epitopes displayed on the same antigen. The possible roles of different T-cell clones, antigen processing, and differential induction of suppressor cells are discussed in relation to these findings.
journal_name
Mol Immunoljournal_title
Molecular immunologyauthors
Wang KM,Reichlin Mdoi
10.1016/0161-5890(88)90115-0subject
Has Abstractpub_date
1988-08-01 00:00:00pages
795-8issue
8eissn
0161-5890issn
1872-9142journal_volume
25pub_type
杂志文章abstract:AIM:To study the role of complement receptor 1 (CR1) for binding of Escherichia coli (E. coli) to erythrocytes, for leukocyte phagocytosis, oxidative burst and complement activation in human whole blood from a CR1 deficient (CR1D) patient and healthy controls with low, medium and high CR1 numbers. METHODS:Alexa-labell...
journal_title:Molecular immunology
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journal_title:Molecular immunology
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doi:10.1016/j.molimm.2007.10.022
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journal_title:Molecular immunology
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journal_title:Molecular immunology
pub_type: 杂志文章
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journal_title:Molecular immunology
pub_type: 杂志文章,评审
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/0161-5890(83)90005-6
更新日期:1983-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:1983-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:1984-08-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
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journal_title:Molecular immunology
pub_type: 杂志文章,评审
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更新日期:2004-02-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/0161-5890(93)90144-z
更新日期:1993-06-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/0161-5890(82)90364-9
更新日期:1982-05-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2020.12.013
更新日期:2020-12-26 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/0161-5890(91)90110-6
更新日期:1991-07-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章,评审
doi:10.1016/j.molimm.2020.10.011
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/j.molimm.2007.09.022
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/0161-5890(93)90451-g
更新日期:1993-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:1996-05-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
doi:10.1016/0161-5890(92)90032-s
更新日期:1992-03-01 00:00:00
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pub_type: 杂志文章
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journal_title:Molecular immunology
pub_type: 杂志文章
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更新日期:2008-03-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2005-03-01 00:00:00
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journal_title:Molecular immunology
pub_type: 杂志文章
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更新日期:2017-02-01 00:00:00
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pub_type: 杂志文章,评审
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