Abstract:
:In this study, a phosphorylation treatment of porous anodic alumina (PAA) was performed by wet impregnation in phosphoric acid and a subsequent heat treatment. The PAA and phosphorylated PAA specimens were analyzed using a field emission scanning electron microscope, an energy-dispersive X-ray spectrometer, and Fourier transform infrared spectroscopy. The apatite-forming ability of the phosphorylated PAA was evaluated by soaking the specimens in simulated body fluid for 1, 3, and 7 days. The surface microstructures and chemical property changes after soaking in simulated body fluid were again characterized by field emission scanning electron microscope, energy-dispersive X-ray spectrometer, and Fourier transform infrared spectroscopy. Results of this study demonstrated that the functional -PO4 groups introduced onto the PAA surface dramatically promoted the deposition of bone-like apatite on PAA. The results from this study indicated that the phosphorylation treatment of anodic alumina is an effective method for inducing bone-like apatite formation, and this phosphorylated PAA can be a promising candidate to be used as bioactive surface coatings on implant metals and alloys for orthopedic and dental applications.
journal_name
J Biomater Appljournal_title
Journal of biomaterials applicationsauthors
Li X,Ni S,Webster TJdoi
10.1177/0885328214526765subject
Has Abstractpub_date
2014-09-01 00:00:00pages
321-8issue
3eissn
0885-3282issn
1530-8022pii
0885328214526765journal_volume
29pub_type
杂志文章abstract::The aim of this study was to compare the osteogenic effects of periodontal ligament stem cells (PDLSCs) versus bone marrow mesenchymal stem cells (BMMSCs) in combination with Bio-Oss scaffolds on subcutaneous and critical-size defects in the immunodeficient rat calvarium. PDLSCs and BMMSCs were obtained from the same ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328214521846
更新日期:2014-08-01 00:00:00
abstract::A range of crystalline and nano-sized carbonate- and silicate-substituted hydroxyapatite has been successfully produced by using continuous hydrothermal flow synthesis technology. Ion-substituted calcium phosphates are better candidates for bone replacement applications (due to improved bioactivity) as compared to pha...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212460289
更新日期:2013-09-01 00:00:00
abstract::Chitosan-glutaraldehyde microparticles were produced by emulsion crosslinking method to be used as drug delivery system for polyphenols from Thymus serpyllum L. aqueous extract. The effect of preparation conditions, chitosan concentration (1.5-3% w/v), and glutaraldehyde/chitosan (GA/Ch) mass ratio (0.15-1.20) on wate...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215598940
更新日期:2015-11-01 00:00:00
abstract::Hemocompatibility is the goal for any biomaterial contained in extracorporeal life supporting medical devices. The hallmarks for hemocompatibility include nonthrombogenicity, platelet preservation, and maintained platelet function. Both in vitro and in vivo assays testing for compatibility of the blood/biomaterial int...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章,评审
doi:10.1177/0885328214538866
更新日期:2014-10-01 00:00:00
abstract::This investigation describes the synthesis and in vitro evaluation of cationic hydrogel sub-microparticles based on polydimethylaminoethylmethacrylate for oral insulin delivery. Polymerization of dimethylaminoethylmethacrylate was carried out in aqueous medium with potassium persulfate as the initiator. Quaternization...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212437392
更新日期:2013-07-01 00:00:00
abstract::An experimental and computational investigation of the self-tapping ability of carbon fibre reinforced polyetheretherketone (CFR-PEEK) has been conducted. Six CFR-PEEK suture anchor designs were investigated using PEEK-OPTIMA® Reinforced, a medical grade of CFR-PEEK. Experimental tests were conducted to investigate th...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328214535274
更新日期:2014-10-01 00:00:00
abstract::Poly(ethylene glycol)-poly(lactic acid) (PEG-PLA) copolymers have been widely used for various biomedical applications. However, their hemocompatibility has not been clarified, which would lag their developments and clinical applications. In this work, we studied the effect of PEG-PLA copolymers on key human blood com...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215627404
更新日期:2016-05-01 00:00:00
abstract::Adhesions commonly occur after internal disease or surgery. The natural healing response leads to the formation of vascular and avascular adhesions after inflammatory diseases and surgical interventions. A barrier film could be incorporated during surgery between layers of tissues that must not adhere to one another. ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829601100203
更新日期:1996-10-01 00:00:00
abstract::In this work, the role of shock wave-induced increase of bone morphogenetic proteins in modulating the osteogenic properties of osteoblast-like cells seeded on a bioactive scaffold was investigated using gremlin as a bone morphogenetic protein antagonist. Bone-like glass-ceramic scaffolds, based on a silicate experime...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328214541974
更新日期:2014-11-01 00:00:00
abstract::Functionalization of a porous orthopedic implant with dexamethasone, a widely used anti-inflammatory drug, encapsulated within a biodegradable polymer for controlled release could help reduce or eliminate the inflammation response by the local tissue. In this research, we investigated the possibility of using supercri...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328209354365
更新日期:2011-01-01 00:00:00
abstract::Sustained intestinal delivery of thiamine hydrochloride (Vitamin B(1); VB(1)) and pyridoxine hydrochloride (Vitamin B(6); VB(6)) seems to be a feasible alternative to existing therapy. The vitamins (VB(1)/VB(6)) intercalated in montmorillonite (MMT) and intercalated VB(1)/VB(6)-MMT hybrid is further used for synthesis...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328209344003
更新日期:2010-08-01 00:00:00
abstract::Fabrication of osteoconductive scaffold with osteoinductive capability and appropriate resorption rate is of great significance for treating bone defects. To achieve this aim, strontium-substituted calcium sulfate hemihydrate (Sr-CSH) and hydroxyapatite (HA) were mixed to develop a novel composite. Sr-CSH containing 5...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328220915816
更新日期:2020-07-01 00:00:00
abstract::Titanium and hydroxyapatite (HA) are widely used as biomaterials for dental and medical applications. HA-coated titanium implants have excellent biocompatibility and mechanical properties. However, the adherence of HA film formed on titanium substrate is weak because of the lack of chemical interaction between HA and ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328209340334
更新日期:2010-03-01 00:00:00
abstract::The aim of this work was to study the cytotoxicity of different fractions of gold nanoparticles prepared by ultrasonic spray pyrolysis from gold scrap. The target cells were rat thymocytes, as a type of nonproliferating cells, and L929 mouse fibroblasts, as a type of continuous proliferating cells. Fractions 1 and 2, ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328210377536
更新日期:2012-01-01 00:00:00
abstract::The controlled release of insulin from a series of biodegradable hybrid hydrogel network containing dextran derivative of allyl isocyanate (dex-AI) and poly (D,L) lactide diacrylate macromer (PDLLAM) over a wide range of composition ratio was investigated. Laser confocal scanning microscope was used to understand the ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1106/088532802024248
更新日期:2002-04-01 00:00:00
abstract::Phase-sensitive in situ gel-forming controlled release formulations of insulin were prepared using poly(lactide-co-glycolide) and a solvent system consisting of various proportions of benzyl benzoate and benzyl alcohol. The in vitro release samples of formulations were assayed for insulin content by enzyme linked immu...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328209359959
更新日期:2011-03-01 00:00:00
abstract::Among biomaterials used as implants in human body, sutures constitute the largest groups of materials having a huge market exceeding $1.3 billion annually. Sutures are the most widely used materials in wound closure and have been in use for many centuries. With the development of the synthetic absorbable polymer, poly...
journal_title:Journal of biomaterials applications
pub_type: 历史文章,杂志文章,评审
doi:10.1177/0885328210384890
更新日期:2010-11-01 00:00:00
abstract::Phenylalanine ethyl ester (PAE)-alginate (Alg) conjugate (PAE-Alg, PEA) was synthesized and formation of an amide bond between PAE and Alg was confirmed by Fourier transformed-infrared and (1)H nuclear magnetic resonance spectroscopy. The degree of PAE substitution was 3.5-4.7 (PAE group per hundred sugar residues of ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328216630497
更新日期:2016-07-01 00:00:00
abstract::The synthesis, tensile strength, thermostability and hydrophilicity of the poly(urethaneamideimide) and the poly(urethaneureas) with N-aliphatic side chains are presented. These elastomers were compared in blood compatibility with determination of the common indices and with immunologic tests of the beta-thromboglobul...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1106/TBUW-TWW9-EC7X-YA3H
更新日期:2000-10-01 00:00:00
abstract::Bone tissue is dependent on an efficient blood supply to ensure delivery of nutrients and oxygen. One method to acquire a vascular-engineered bone tissue could be the use of an angiogenic gene-activated scaffold. In the current study, porous chitosan/hydroxyapatite (C/HA) scaffolds were fabricated via freeze-drying wi...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328214544769
更新日期:2014-11-01 00:00:00
abstract::The aim of this study was to design a new natural/synthetic bioactive bone scaffold for potential use in bone replacement applications. We developed a tri-component osteogenic composite scaffold made of collagen (Coll), hydroxyapatite (HA) and poly(l-lactide-co-ε-caprolactone) (PLCL). This Coll/HA/PLCL composite scaff...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328213486705
更新日期:2014-02-01 00:00:00
abstract::The layer-by-layer technique, which allows simple preparation of polyelectrolyte multilayers, came into the focus of research for development of functionalized medical devices. Numerous literature exist that concentrate on the film build-up and the behaviour of cells on polyelectrolyte multilayers. However, in case of...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212437610
更新日期:2013-07-01 00:00:00
abstract::Single nanofibers with chemical and functional properties consistent with artery extracellular matrix nanofibers were produced by electrospinning. Using weight ratios to mimic artery extracellular matrix, five materials were tested: (1) Collagen type I, (2) Collagen type I + Collagen type III, (3) Collagen type I + po...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328213477893
更新日期:2014-01-01 00:00:00
abstract::Devices such as contact lenses and collagen shields have been used to improve the antibiotic bioavailability of eye drops formulations in the treatment of ulcerative keratitis. Nevertheless, these devices are not sustained drug delivery systems, and a combination with eye drops is necessary. In animal patients, it req...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328220931733
更新日期:2020-09-01 00:00:00
abstract::Melt electrowriting (MEW) can print high-resolution scaffolds with the ultrafine fibers from 800 nm to 20 µm. However, the cell seeding efficiency relatively low due to the large pore size of the MEW scaffold. Here, we reported a method to solve this dilemma by electrospinning a gelatin methacrylate (GelMA) hydrogel f...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328220962606
更新日期:2021-01-01 00:00:00
abstract::In this work, gold embedded chitosan nanoparticles (Au@CS NPs) were fabricated by a one-pot method. The benzaldehyde-terminated poly[(2-methacryloyloxy) ethyl phosphorylcholine] (PMPC) was applied to modification of the gold doped chitosan nanoparticles. The obtained Au@CS-PMPC NPs had the diameter of 135 nm with a na...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328220952594
更新日期:2020-08-27 00:00:00
abstract::The aim of this pilot study was to evaluate the bioactive, surface-coated polycaprolactone-co-lactide scaffolds as bone implants in a tibia critical size defect model. Polycaprolactone-co-lactide scaffolds were coated with collagen type I and chondroitin sulfate and 30 piled up polycaprolactone-co-lactide scaffolds we...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212471409
更新日期:2014-01-01 00:00:00
abstract::Staphylococcus epidermidis plays a major role in capsular contractures of silicone breast implants. This in vitro study evaluates the antibacterial effect of copper on S. epidermidis in silicone implants. Specimens of a silicone material used for breast augmentation (Cu0) and specimens coated with different copper con...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212441957
更新日期:2013-08-01 00:00:00
abstract::Even though Ti-based implants are the most used materials for hard tissue replacement, they may present lack of osseointegration on the long term, due to their inertness. Hydrothermal treatment (HT) is a useful technique for the synthesis of firmly attached, highly crystalline coatings made of anatase titanium dioxide...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215569091
更新日期:2015-07-01 00:00:00
abstract::Carbon-fibre-reinforced polyether ether ketone (CFR-PEEK) exhibits excellent biomechanical properties as it has an elastic modulus similar to bone. However, CFR-PEEK displays inferior biocompatibility compared with titanium alloy and coating techniques are therefore of interest in order to improve integration. In this...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328214521669
更新日期:2014-08-01 00:00:00