Sodium-glucose cotransporter 2 inhibition and glycemic control in type 1 diabetes: results of an 8-week open-label proof-of-concept trial.

abstract：:Biosynthetic human insulin (BHI) and purified pork insulin (PPI) were compared for binding properties and stimulatory effect on 2-deoxyglucose transport in isolated rat fat cells. No difference between these types of insulin could be demonstrated. ...

journal_title：Diabetes care

authors： Wieringa T,van Putten JP,Van Dijk-Besling M,Krans HM

更新日期：1981-03-01 00:00:00

abstract：OBJECTIVE:Glycemic control (HbA(1c) [A1C]) is strongly associated with microvascular disease in individuals with diabetes, but its relation to macrovascular disease and atherosclerosis is less clear. This study examines the relationship between A1C, carotid intima-media thickness (IMT), and traditional cardiovascular r...

journal_title：Diabetes care

authors： Selvin E,Coresh J,Golden SH,Boland LL,Brancati FL,Steffes MW,Atherosclerosis risk in communities study.

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:This systematic review and meta-analysis of randomized controlled trials (RCTs) assesses the effect of pharmacist care on cardiovascular disease (CVD) risk factors among outpatients with diabetes. RESEARCH DESIGN AND METHODS:MEDLINE, EMBASE, CINAHL, and the Cochrane Central Register of Controlled Trials were...

journal_title：Diabetes care

authors： Santschi V,Chiolero A,Paradis G,Colosimo AL,Burnand B

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of hypoglycemia in patients with type I diabetes and impaired awareness of hypoglycemia by prospective assessment. RESEARCH DESIGN AND METHODS:A prospective study was undertaken for 12 months in 60 patients with type I diabetes: 29 had impaired awareness of hypoglycemia and 31 reta...

journal_title：Diabetes care

authors： Gold AE,MacLeod KM,Frier BM

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:To assess effectiveness of inpatient hybrid closed-loop control (HCLC) followed by outpatient sensor-augmented pump (SAP) therapy initiated within 7 days of diagnosis of type 1 diabetes on the preservation of β-cell function at 1 year. RESEARCH DESIGN AND METHODS:Sixty-eight individuals (mean age 13.3 ± 5.7 ...

journal_title：Diabetes care

authors： Buckingham B,Beck RW,Ruedy KJ,Cheng P,Kollman C,Weinzimer SA,DiMeglio LA,Bremer AA,Slover R,Tamborlane WV,Diabetes Research in Children Network (DirecNet) Study Group.,Type 1 Diabetes TrialNet Study Group.

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:Raloxifene hydrochloride is a selective estrogen receptor modulator that to date has not been shown to cause hypertriglyceridemia in normal, diabetic, or hypertriglyceridemic women. This study was designed to assess the effect of raloxifene on serum triglycerides in postmenopausal women who have a history of ...

journal_title：Diabetes care

authors： Carr MC,Knopp RH,Brunzell JD,Wheeler BS,Zhu X,Lakshmanan M,Rosen AS,Anderson PW

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To investigate the association between vitamin D status, assessed by plasma 25-hydroxyvitamin D, and risk of incident diabetes. RESEARCH DESIGN AND METHODS:Prospective observational study with a mean follow-up of 2.7 years in the Diabetes Prevention Program (DPP), a multicenter trial comparing different stra...

journal_title：Diabetes care

authors： Pittas AG,Nelson J,Mitri J,Hillmann W,Garganta C,Nathan DM,Hu FB,Dawson-Hughes B,Diabetes Prevention Program Research Group.

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To compare the effect of morning and bedtime NPH insulin combined with daytime sulfonylurea on glycemic control in non-insulin-dependent diabetes mellitus (NIDDM) patients no longer responding to treatment with sulfonylureas alone. RESEARCH DESIGN AND METHODS:Twenty-four NIDDM patients who fulfilled these cr...

journal_title：Diabetes care

authors： Groop LC,Widén E,Ekstrand A,Saloranta C,Franssila-Kallunki A,Schalin-Jäntti C,Eriksson JG

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:No prospective, community-based cohort studies have investigated the association between blood pressure and diabetes in Asian ethnicity. We investigated this issue in a 10-year prospective, community-based study of Koreans. RESEARCH DESIGN AND METHODS:We studied whether high blood pressure was associated wit...

journal_title：Diabetes care

authors： Cho NH,Kim KM,Choi SH,Park KS,Jang HC,Kim SS,Sattar N,Lim S

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To determine whether folate metabolism in pregnant diabetic women is significantly different from that in pregnant nondiabetic women, thus predisposing them to having offspring with major congenital anomalies. RESEARCH DESIGN AND METHODS:A total of 31 pregnant diabetic women and 54 pregnant nondiabetic contr...

journal_title：Diabetes care

authors： Kaplan JS,Iqbal S,England BG,Zawacki CM,Herman WH

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To project the number of people with diagnosed diabetes in the U.S. through 2050, accounting for changing demography and diabetes prevalence rates. RESEARCH DESIGN AND METHODS:We combined age-, sex-, and race-specific diagnosed diabetes prevalence rates-predicted from 1980-1998 trends in prevalence data from...

journal_title：Diabetes care

authors： Boyle JP,Honeycutt AA,Narayan KM,Hoerger TJ,Geiss LS,Chen H,Thompson TJ

更新日期：2001-11-01 00:00:00

abstract：:The effects of intravenous administration of potassium phosphate in the treatment of diabetic ketoacidosis were studied in nine children, ages 9 9/12 to 17 10/12 yr. During phosphate infusion (20--40 meq/L of fluid), all children maintained normal serum concentrations of phosphorus. Transient hypocalcemia occurred in ...

journal_title：Diabetes care

authors： Zipf WB,Bacon GE,Spencer ML,Kelch RP,Hopwood NJ,Hawker CD

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:To assess performance of nonfasting tests to screen children for dysglycemia (prediabetes or diabetes). RESEARCH DESIGN AND METHODS:This was a cross-sectional study of 254 overweight or obese (BMI ≥85th percentile) children aged 10-17 years. Subjects came for two visits to a clinical research unit. For visit...

journal_title：Diabetes care

authors： Lee JM,Gebremariam A,Wu EL,LaRose J,Gurney JG

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence of diabetes and impaired glucose tolerance (IGT) in the adult population of Rio de Janeiro, a two-stage cross-sectional survey was carried out in a random sample of 2,051 individuals aged 30-69 years from Rio de Janeiro city in Brazil. RESEARCH DESIGN AND METHODS:Subjects were first ...

journal_title：Diabetes care

authors： Oliveira JE,Milech A,Franco LJ

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:To assess the costs and project the potential lifetime cost-effectiveness of the ongoing Autoimmunity Screening for Kids (ASK) program, a large-scale, presymptomatic type 1 diabetes screening program for children and adolescents in the metropolitan Denver region. RESEARCH DESIGN AND METHODS:We report the res...

journal_title：Diabetes care

authors： McQueen RB,Geno Rasmussen C,Waugh K,Frohnert BI,Steck AK,Yu L,Baxter J,Rewers M

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:High-deductible health plans (HDHPs) are now the predominant commercial health insurance benefit in the U.S. We sought to determine the effects of HDHPs on emergency department and hospital care, adverse outcomes, and total health care expenditures among patients with diabetes. RESEARCH DESIGN AND METHODS:We...

journal_title：Diabetes care

authors： Wharam JF,Zhang F,Eggleston EM,Lu CY,Soumerai SB,Ross-Degnan D

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of glyburide versus metformin and their combination for the treatment of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS:In this prospective randomized controlled study, we randomly assigned patients with GDM at 13-33 weeks gestation and whose blood glucose...

journal_title：Diabetes care

authors： Nachum Z,Zafran N,Salim R,Hissin N,Hasanein J,Gam Ze Letova Y,Suleiman A,Yefet E

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To describe an etiologic approach to classification of diabetes types in youth based on the 1997 American Diabetes Association (ADA) framework, using data from the SEARCH for Diabetes in Youth Study. RESEARCH DESIGN AND METHODS:SEARCH conducted a comprehensive assessment of 2,291 subjects aged <20 years with...

journal_title：Diabetes care

authors： Dabelea D,Pihoker C,Talton JW,D'Agostino RB Jr,Fujimoto W,Klingensmith GJ,Lawrence JM,Linder B,Marcovina SM,Mayer-Davis EJ,Imperatore G,Dolan LM,SEARCH for Diabetes in Youth Study.

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:Many patients with early diabetes remain untreated. Our objectives were to identify clinical predictors of 1) worsening glycemic control and 2) medical treatment initiation in response to worsening glycemic control among patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:We identified 5,804 type 2 di...

journal_title：Diabetes care

authors： Pani LN,Nathan DM,Grant RW

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To detect clinical correlates of cognitive abilities and white matter (WM) microstructural changes using diffusion tensor imaging (DTI) in young children with type 1 diabetes. RESEARCH DESIGN AND METHODS:Children, ages 3 to <10 years, with type 1 diabetes (n = 22) and age- and sex-matched healthy control sub...

journal_title：Diabetes care

authors： Aye T,Barnea-Goraly N,Ambler C,Hoang S,Schleifer K,Park Y,Drobny J,Wilson DM,Reiss AL,Buckingham BA

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:HbA1c is strongly related to the development of diabetes complications, but it is still controversial which HbA1c level to strive for in the treatment of type 1 diabetes. The aim of the current study was to evaluate HbA1c, followed from diagnosis, as a predictor of severe microvascular complications and to fo...

journal_title：Diabetes care

authors： Nordwall M,Abrahamsson M,Dhir M,Fredrikson M,Ludvigsson J,Arnqvist HJ

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To determine, after 1 yr of follow-up in type II diabetes patients, whether a statistically and clinically significant difference can be achieved in HbA1c between a standard therapy group and an intensively treated group, while maintaining HbA1c levels in both groups within ranges acceptable in regular commun...

journal_title：Diabetes care

authors： Abraira C,Emanuele N,Colwell J,Henderson W,Comstock J,Levin S,Nuttall F,Sawin C

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between cigarette smoking and mortality among women with type 2 diabetes in the Nurses' Health Study cohort. RESEARCH DESIGN AND METHODS:The Nurses' Health Study, a prospective cohort of U.S. female registered nurses, included 7,401 women with type 2 diabetes diagnosed at baseline ...

journal_title：Diabetes care

authors： Al-Delaimy WK,Willett WC,Manson JE,Speizer FE,Hu FB

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:Early puberty is associated with increased risk of subsequent cardiovascular disease. Low sex hormone-binding globulin (SHBG) levels are a feature of early puberty and of conditions associated with increased cardiovascular risk. The aim of the present study was to evaluate SHBG as a predictor of glucose metab...

journal_title：Diabetes care

authors： Sørensen K,Aksglaede L,Munch-Andersen T,Aachmann-Andersen NJ,Petersen JH,Hilsted L,Helge JW,Juul A

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:Roux-en-Y gastric bypass (RYGB) ameliorates type 2 diabetes in severely obese patients through mechanisms beyond just weight loss, and it may benefit less obese diabetic patients. We determined the long-term impact of RYGB on patients with diabetes and only class I obesity. RESEARCH DESIGN AND METHODS:Sixty-...

journal_title：Diabetes care

authors： Cohen RV,Pinheiro JC,Schiavon CA,Salles JE,Wajchenberg BL,Cummings DE

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To develop and validate a scale for acanthosis nigricans (AN). RESEARCH DESIGN AND METHODS:Subjects were participants from the San Antonio Family Diabetes Study and the San Antonio Family Heart Study. A total of 406 subjects were independently examined for AN by at least two observers. Five locations were ex...

journal_title：Diabetes care

authors： Burke JP,Hale DE,Hazuda HP,Stern MP

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Numerous publications have already demonstrated that diabetes is a risk factor for the development of periodontal diseases and various inflammatory lesions in the oral mucosa. A possible correlation between diabetes and oral premalignancies and tumors was examined in this study, as no literature data are avai...

journal_title：Diabetes care

authors： Ujpál M,Matos O,Bíbok G,Somogyi A,Szabó G,Suba Z

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:Given the role of gut microbiota in regulating metabolism, probiotics administered during pregnancy might prevent gestational diabetes mellitus (GDM). This question has not previously been studied in high-risk overweight and obese pregnant women. We aimed to determine whether probiotics (Lactobacillus rhamnos...

journal_title：Diabetes care

authors： Callaway LK,McIntyre HD,Barrett HL,Foxcroft K,Tremellen A,Lingwood BE,Tobin JM,Wilkinson S,Kothari A,Morrison M,O'Rourke P,Pelecanos A,Dekker Nitert M

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of the erythromycin derivative EM523L on gastric emptying and postprandial insulin requirement in insulin-dependent diabetic patients with severe gastroparesis. RESEARCH DESIGN AND METHODS:In six IDDM patients with severe gastroparesis (two men and four women, mean age 44.5 years [rang...

journal_title：Diabetes care

authors： Ishii M,Nakamura T,Kasai F,Baba T,Takebe K

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:To determine the effect of diabetes on thyroid hormone and thyroxine-binding globulin (TBG) concentrations during puberty. RESEARCH DESIGN AND METHODS:Total thyroxine (TT4), free thyroxine (FT4), and TBG levels of 171 thyroid microsomal antibody-negative subjects with normal thyroid-stimulating hormone (TSH)...

journal_title：Diabetes care

authors： Connors MH,Dunger DB,Chapel H,Jefferson I,Jowett TP,Edwards PR

更新日期：1996-03-01 00:00:00