Patient response to awake craniotomy - a summary overview.


BACKGROUND:Awake craniotomy is a valuable procedure since it allows brain mapping and live monitoring of eloquent brain functions. The advantage of minimizing resource utilization is also emphasized by some physicians in North America. Data on how well an awake craniotomy is tolerated by patients and how much stress it creates is available from different studies, but this topic has not consequently been summarized in a review of the available literature. Therefore, it is the purpose of this review to shed more light on the still controversially discussed aspect of an awake craniotomy. METHODS:We reviewed the available English literature published until December 2013 searching for studies that investigated patients' responses to awake craniotomies. RESULTS:Twelve studies, published between 1998 and 2013, including 396 patients with awake surgery were identified. Eleven of these 12 studies set the focus on the perioperative time, one study focused on the later postoperative time. The vast majority of patients felt well prepared and overall satisfaction with the procedure was high. In the majority of studies up to 30 % of the patients recalled considerable pain and 10-14 % experienced strong anxiety during the procedure. The majority of patients reported that they would undergo an awake craniotomy again. A post traumatic stress disorder was present neither shortly nor years after surgery. However, a normal human response to such an exceptional situation can for instance be the delayed appearance of unintentional distressing recollections of the event despite the patients' satisfaction concerning the procedure. CONCLUSIONS:For selected patients, an awake craniotomy presents the best possible way to reduce the risk of surgery related neurological deficits. However, benefits and burdens of this type of procedure should be carefully considered when planning an awake craniotomy and the decision should serve the interests of the patient.


Acta Neurochir (Wien)


Acta neurochirurgica


Milian M,Tatagiba M,Feigl GC




Has Abstract


2014-06-01 00:00:00












  • Spontaneous regression of a parafalcine meningioma in a multiple sclerosis patient being treated with interferon beta-1a.

    abstract::Regression of meningioma after haemorrhage and the cessation of hormone treatment is well reported. However, spontaneous regression is very rarely observed. Here, we report the spontaneous regression of a parafalcine meningioma in a 56-year-old woman with multiple sclerosis, who was referred to our department after an...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Galloway L,Vakili N,Spears J

    更新日期:2017-03-01 00:00:00

  • Cyst fluid of glioma does not inhibit the killing action of lymphokine-activated killer (LAK) cells in vitro.

    abstract::In theory, lymphokine-activated killer (LAK) cells offer a potential method to treat cerebral gliomas, especially low-grade gliomas. LAK cells would be administered by repeated injections straight into the cavity of a subtotally removed tumour. However, brain-tumour cyst fluid has been shown to be immunosuppressive in...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Jääskeläinen J,Kalliomäki P,Paetau A,Saksela E,Timonen T

    更新日期:1988-01-01 00:00:00

  • Near-infrared indocyanine green videoangiography versus microvascular Doppler sonography in aneurysm surgery.

    abstract:INTRODUCTION:The quality of surgical treatment of intracranial aneurysms is determined by complete aneurysm occlusion and restoration of flow in the parent, branching and perforating vessels. In postoperative digital subtraction angiography (DSA), unexpected aneurysm residuals and vessel occlusions are frequently detec...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Fischer G,Stadie A,Oertel JM

    更新日期:2010-09-01 00:00:00

  • Triceps brachii reinnervation in primary reconstruction of the adult brachial plexus: experience in 25 cases.

    abstract:BACKGROUND:Elbow flexion and shoulder abduction are the primary goals in brachial plexus surgery; however, reinnervation of the triceps is also an objective to be considered, as restoration of elbow extension improves the stabilization of the elbow and can provide a more powerful grasp. This study aims to demonstrate t...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Flores LP

    更新日期:2011-10-01 00:00:00

  • Impact of antibiotic-impregnated catheters on the timing of cerebrospinal fluid infections in non-traumatic subarachnoid hemorrhage.

    abstract:BACKGROUND:Subarachnoid hemorrhage (SAH) has been recognized as a risk factor for ventriculostomy-related infections (VRI). In addition to the hemorrhagic cerebrospinal fluid (CSF), the potential need for prolonged catheterization may contribute to the increased CSF infection rate in this population. The use of antibio...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: McLaughlin N,St-Antoine P,Bojanowski MW

    更新日期:2012-04-01 00:00:00

  • Trauma- and distress-associated mental illness symptoms in close relatives of patients with severe traumatic brain injury and high-grade subarachnoid hemorrhage.

    abstract:BACKGROUND:Close relatives (CR) of patients with severe traumatic brain injury (TBI) and high-grade subarachnoid hemorrhage (SAH) suffer extraordinary distress during the treatment: Distress may lead to persisting mental illness symptoms within the spectrum of post-traumatic stress disorder (PTSD), anxiety disorders, a...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Rueckriegel SM,Baron M,Domschke K,Neuderth S,Kunze E,Kessler AF,Nickl R,Westermaier T,Ernestus RI

    更新日期:2015-09-01 00:00:00

  • Small acoustic neuromas: monitoring the growth rate by MRI.

    abstract::In a proportion of small acoustic neuroma patients, monitoring with magnetic resonance imaging shows no volumetric increase of tumour size over the years. The object of the study was to identify some indications for the clinical choice between immediate surgery (with the related risks) and watchful waiting. We perform...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Modugno GC,Pirodda A,Ferri GG,Fioravanti A,Calbucci F,Pezzi A,Ceroni AR,Pirodda E

    更新日期:1999-01-01 00:00:00

  • Cytotoxic immune response of meningioma patients towards allogeneic and autologous tumour cells before and after surgery.

    abstract::Cell-mediated cytotoxicity (CTX) of meningioma patients towards meningioma cells and fibroblasts was studied in vitro before and after surgery, using the 3H-proline microcytotoxicity test. When incubated with allogeneic target cells before surgery, lymphocytes from three out of seven donors showed a specific destructi...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Pees HW

    更新日期:1979-01-01 00:00:00

  • Primary intraspinal cervical melanoma.

    abstract::A case of primary intraspinal melanoma is presented. This is a very rarely observed lesion, as only 37 cases have been described up to now. Patient presenting with signs and symptoms of spinal cord compression after MRI and spinal angiography was operated upon. Total removal of an intraspinal cervical tumour was perfo...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Bidziński J,Kroh H,Leszczyk C,Bojarski P

    更新日期:2000-01-01 00:00:00

  • Venous malformation in the posterior fossa: guidelines for treatment.

    abstract::Venous malformations in the posterior fossa are relatively rare. Although the introduction of CT and MRI has made them easier to detect, their treatment is still controversial. Based on our experience with six patients and a review of the literature, we have tried to establish guidelines for their treatment. Since the...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Mori K,Seike M,Kurisaka M,Kamimura Y,Morimoto M

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  • Critical review of brain AVM surgery, surgical results and natural history in 2017.

    abstract:BACKGROUND:An understanding of the present standing of surgery, surgical results and the role in altering the future morbidity and mortality of untreated brain arteriovenous malformations (bAVMs) is appropriate considering the myriad alternative management pathways (including radiosurgery, embolization or some combinat...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章,评审


    authors: Morgan MK,Davidson AS,Assaad NNA,Stoodley MA

    更新日期:2017-08-01 00:00:00

  • Accumulation of PN1 and PN3 sodium channels in painful human neuroma-evidence from immunocytochemistry.

    abstract:BACKGROUND:The axolemmal distribution and density of voltage-gated sodium channels largely determines the electrical excitability of sprouting neurites. Recent evidence suggests that accumulation of sodium channels at injured axonal tips may be responsible for ectopic axonal hyperexcitability and the resulting abnormal...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Kretschmer T,Happel LT,England JD,Nguyen DH,Tiel RL,Beuerman RW,Kline DG

    更新日期:2002-08-01 00:00:00

  • Vertebral artery decompression in a patient with rotational occlusion.

    abstract::We report a patient who suffered drop attacks during head reclination. Computer tomography of the cervical spine demonstrated a stenotic right vertebral artery at C4/5. However, Doppler ultrasonography of the vertebral artery showed no abnormality. Angiography confirmed complete occlusion of the left vertebral and a s...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Petridis AK,Barth H,Buhl R,Mehdorn HM

    更新日期:2008-04-01 00:00:00

  • Immunopathological significance of IgG in meningioma in relation to the pseudopsammoma bodies.

    abstract::We described two histochemical patterns of IgG deposits in meningioma and discussed the pathogenesis of IgG deposits. In meningioma with pseudopsammoma bodies, IgG was secreted from tumour cells which differentiated to secretory epithelial cells, and was found to deposit in the pseudopsammoma bodies. However, in menin...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Kuratsu J,Matsukado Y,Hattori R,Nagahiro S

    更新日期:1985-01-01 00:00:00

  • Experiences on two different stereotactic radiosurgery modalities of Gamma Knife and Cyberknife in treating brain metastases.

    abstract:BACKGROUND:In this study, we compared the dosimetric properties between Gamma Knife (GK) and Cyberknife (CK), and investigated the clinical implications in treating brain metastases (BMs). METHODS:Between 2011 and 2013, 77 patients treated with either single-fraction GK for small BMs (n = 40) or fractionated CK for la...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Cho YH,Lee JM,Lee D,Park JH,Yoon K,Kim SO,Kwon DH,Kim JH,Kim CJ,Roh SW

    更新日期:2015-11-01 00:00:00

  • Clinical features and management of brain arteriovenous malformations in elderly patients.

    abstract:BACKGROUND:Brain arteriovenous malformations (AVMs) of the elderly have not received sufficient attention, given the increase in age of individuals in recent years. We therefore designed a retrospective study to clarify features of brain AVMs in this age group in comparison with their counterparts in the general popula...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Hashimoto H,Iida J,Kawaguchi S,Sakaki T

    更新日期:2004-10-01 00:00:00

  • Effect of ketanserin on 5-hydroxytryptamine-induced constriction in isolated, perfused canine basilar arteries exposed to blood.

    abstract::The blocking effect of ketanserin, a 5-hydroxytryptamine (5-HT)2 receptor antagonist, was examined on responses to intra-luminal 5-HT or potassium chloride (KCl) in isolated and perfused canine basilar arteries before and after extraluminal whole blood by means of the stainless-steel cannula inserting method. Four hou...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Tsuji T,Cook DA

    更新日期:1996-01-01 00:00:00

  • Early post-operative ACTH and cortisol as predictors of remission in Cushing's disease.

    abstract:AIM:To study the value of early (24 h) post-operative ACTH and serum cortisol as predictors of remission after transsphenoidal surgery in Cushing's disease. METHODS:We prospectively studied 44 patients who underwent transsphenoidal surgery for Cushing's disease between 1997 and 2005. The mean follow-up period of patie...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Acebes JJ,Martino J,Masuet C,Montanya E,Soler J

    更新日期:2007-01-01 00:00:00

  • Association of intraneural perineurioma with neurofibromatosis type 2.

    abstract:BACKGROUND:Neurofibromatosis type 2 (NF2) is a genetic disorder characterized by mutations of the NF2 tumor suppressor gene that predisposes patients to develop multiple tumors in the peripheral and central nervous system. The most common neoplasms associated with the disease are schwannomas and meningiomas. Both have ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Pendleton C,Spinner RJ,Dyck PJB,Mauermann ML,Ladak A,Restrepo CE,Baheti S,Klein CJ

    更新日期:2020-08-01 00:00:00

  • Treatment of patients with ruptured aneurysm by neurosurgeons that perform both open surgical and endovascular techniques is safe and effective: results of a single centre in Europe.

    abstract::In Europe only few neurosurgeons are trained in both open surgical clipping as well as in endovascular techniques for treatment of intracranial aneurysms. To investigate the safety and efficacy of performing both techniques we, two dual trained neurosurgeons, analyzed our results in repairing ruptured intracranial ane...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: de Vries J,Boogaarts HD

    更新日期:2014-07-01 00:00:00

  • Linear accelerator and Greitz-Bergstrom's head fixation system in radiosurgery of single cerebral metastases. A report of 86 cases.

    abstract::Between 1984 and 1991 86 patients with single cerebral metastases underwent linear accelerator radiosurgery using the atraumatic and reproducible Greitz-Bergström head-fixation device. Routine one-month follow-up documented disappearance of the tumour in 16 patients, with resolution of the oedema and ventricular shift...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Valentino V,Mirri MA,Schinaia G,Dalle Ore G

    更新日期:1993-01-01 00:00:00

  • Microsurgical resection of an intramedullary glomus arteriovenous malformation in the high cervical spinal cord: retrograde dissection techniques of the nidus located between spinal tracts.

    abstract:BACKGROUND:Spinal intramedullary arteriovenous malformations (AVMs) fed by an anterior spinal artery are surgically challenging vascular lesions. METHOD:We herein presented microsurgical resection techniques for an intramedullary glomus AVM located in the lateral part of the high cervical spinal cord with an operative...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Takai K,Taniguchi M

    更新日期:2015-10-01 00:00:00

  • The role of Gamma Knife radiosurgery in the treatment of pineal parenchymal tumours.

    abstract:OBJECT:The aim of this study was to document the possible role of Gamma Knife radiosurgery, suitable for the treatment of deep and well limited tumors, in the management of pineal parenchymal tumors (PPT). POPULATION AND METHODS:We reviewed retrospectively a series of 13 patients with PPT treated by Gamma Knife radios...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Reyns N,Hayashi M,Chinot O,Manera L,Péragut JC,Blond S,Régis J

    更新日期:2006-01-01 00:00:00

  • Ventricular shunt survival in children with neural tube defects.

    abstract::Ventricular shunting has dramatically improved the care of children with hydrocephalus. Yet shunt malfunctions are extremely common and cause significant morbidity. To document shunt problems in children with a neural tube defect and hydrocephalus, 67 children born since 1973 were studied via life-table analysis. 28% ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Liptak GS,Masiulis BS,McDonald JV

    更新日期:1985-01-01 00:00:00

  • iNOS-mediated secondary inflammatory response differs between rat strains following experimental brain contusion.

    abstract:BACKGROUND:Nitric oxide is a key mediator of post-traumatic inflammation in the brain. We examined the expressions of iNOS, nNOS, and eNOS in inbred DA and PVGa rat strains where DA is susceptible to autoimmune neuroinflammation and PVGa-resistant. METHODS:Parietal contusions using a weight drop model were produced in...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Günther M,Al Nimer F,Gahm C,Piehl F,Mathiesen T

    更新日期:2012-04-01 00:00:00

  • Lumbo-omental shunt for drainage of cerebrospinal fluid--an experimental radionuclide study in dogs. II. Evaluation of transport routes from lumbar subarachnoid space to venous blood.

    abstract::In a series of dogs, the transport routes of intrathecally administered 99Tcm-DTPA from an omental graft to the venous blood were studied by scintillation probes placed over the portal and external jugular veins and by blood samples from the inferior vena cava. It was found early in the course of investigation that a ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Levander B,Asard PE

    更新日期:1978-01-01 00:00:00

  • Utility of surgery in the treatment of epidural vertebral metastases.

    abstract::Treatment of vertebral epidural metastases has been in the past and still remains the object of special attention in an attempt to improve the quality of life of these patients. To assess the effects of and indications for surgery, the clinical histories of 53 patients with this malignant disease who had undergone dec...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: García-Picazo A,Capilla Ramírez P,Pulido Rivas P,Garcia de Sola R

    更新日期:1990-01-01 00:00:00

  • Angiographic investigation of cerebral vasospasm in subarachnoid haemorrhage due to arteriovenous malformation.

    abstract::Fifty (50) selected patients with arteriovenous malformation (AVM) with and without subarachnoid haemorrhage (SAH) were investigated, in respect of occurrence and course of the vasospasm. The diameters of the carotid siphon and its main branches were measured and plotted against the time elapsing between the haemorrha...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: von Holst H,Ericson K,Haberbeck-Modesto M,Steiner L

    更新日期:1988-01-01 00:00:00

  • Accuracy of subthalamic nucleus targeting by T2, FLAIR and SWI-3-Tesla MRI confirmed by microelectrode recordings.

    abstract:BACKGROUND:Successful deep brain stimulation is mostly dependent on accurate positioning of the leads at the optimal target points. We investigated whether the identification of the subthalamic nucleus in T2-weighted 3-T MRI, fluid-attenuated inversion recovery 3-T MRI and susceptibility-weighted 3-T MRI is confirmed b...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章


    authors: Polanski WH,Martin KD,Engellandt K,von Kummer R,Klingelhoefer L,Fauser M,Storch A,Schackert G,Sobottka SB

    更新日期:2015-03-01 00:00:00

  • Molecular pathogenesis of astrocytoma and glioblastoma multiforme.

    abstract::Our understanding of the complexity of genetic abnormalities involved in the tumourigenesis of malignant gliomas is as yet rudimentary. However, we can discern distinctive patterns of loss of genetic material and amplification of chromosomal regions that characterize both the different types of gliomas as well as the ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章,评审


    authors: Van de Kelft E

    更新日期:1997-01-01 00:00:00